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[会议论文] 作者:Jun-Ho Lee,Chul-Kyu Park,Gang Chen,Qingjian Han,Rou-Gang Xie,Tong Liu,Ru-Rong Ji,Seok-Yong Lee,
来源:The 6th FAONS Congress and 11th Biennial Conference of CNS(第 年份:2015
Voltage-gated sodium(NaV)channels control the upstroke of the action potentials in excitable cells.Multiple studies have shown distinct roles of NaV channel subtypes in human physiology and diseases,b...
Differential Inhibition of Nav1.7 and Neuropathic Pain by Hybridoma-Produced and Recombinant Monoclo
[期刊论文] 作者:Sangsu Bang,Jiho Yoo,Xingrui Gong,Di Liu,Qingjian Han,Xin Luo,Wonseok Chang,Gang Chen,Sang-Taek Im,Yong,
来源:神经科学通报(英文版) 年份:2018
The voltage-gated Na+ channel subtype Nav1.7 is important for pain and itch in rodents and humans.We previously showed that a Navl.7-targeting monoclonal antibody (SVmab) reduces Na+ currents and pain and itch responses in mice.Here,we inve......
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