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[期刊论文] 作者:Rafael Rosell, 来源:世界呼吸病学杂志 年份:2011
Congratulations to the publisher,members of the editorial board of the journal,and all the authors and readers for launching the World Journal of Respirology(WJ...
[期刊论文] 作者:Niki Karachaliou,Rafael Rosell,, 来源:Cancer Biology & Medicine 年份:2014
Lung cancer is the most frequently diagnosed cancer and a leading cause of cancer mortality worldwide, with adenocarcinoma being the most common histological su...
[期刊论文] 作者:Rafael Rosell,Niki Karachaliou, 来源:临床与病理杂志 年份:2015
人们普遍认为有必要对非小细胞肺癌进行分子层面的分析.例如,基于EGFR突变状态的治疗已经得到了很好的研究结果.尽管口服EGFR酪氨酸激酶抑制剂(TKIs)在初始治疗中能够取得较...
[期刊论文] 作者:Niki Karachaliou,Rafael Rosell, 来源:临床与病理杂志 年份:2015
SOX2是在胚胎发育中发挥关键作用的干细胞转录因子,它是一组能使人类体细胞转化成多能干细胞的因子(Oct4,SOX2,Nanog)的基因之一.SOX2的过度表达在各种肺癌组织类型如肺小细...
[期刊论文] 作者:Rafael Rosell,Ramón Palme, 来源:癌症生物学与医学:英文版 年份:2015
Cancer evades host immune surveillance by using immune checkpoints,w hich are inhibitor y pathways cr ucial for maintaining self-tolerance1.Tumor cells expr...
[期刊论文] 作者:Rafael Rosell,Ramón Palmero,, 来源:Cancer Biology & Medicine 年份:2015
Cancer evades host immune surveillance by using immune checkpoints,w hich are inhibitor y pathways cr ucial for maintaining self-tolerance1.Tumor cells express...
[期刊论文] 作者:Cristina Teixidó,Niki Karachaliou,Maria González-Cao,Daniela Morales-Espinosa,Rafael Rosell,, 来源:Cancer Biology & Medicine 年份:2015
Immunotherapy has become a key strategy for cancer treatment, and two immune checkpoints, namely, programmed cell death 1(PD-1) and its ligand(PD-L1), have rece...
[期刊论文] 作者:Cristina Teixidó,Niki Karachaliou,Maria González-Cao,Daniela Morales-Espinosa,Rafael Rosell,, 来源:Cancer Biology & Medicine 年份:2015
In the published article1,one error appeared on page 89.Pembrolizumab has not yet received FDA approval for NSCLC patients.In October 2014 pembrolizumab receive...
[期刊论文] 作者:María Gonzalez-Cao,Paola Iduma,Niki Karachaliou,Mariacarmela Santarpia,Julià Blanco,Rafael Rosell,, 来源:Cancer Biology & Medicine 年份:2016
Human endogenous retroviruses(HERVs) are retroviruses that infected human genome millions of years ago and have persisted throughout human evolution. About 8% o...
[期刊论文] 作者:Gonzalez Cao,Cristina Teixidó,Santiago Viteri,Daniela Morales-Espinosa,Mariacarmela Santarpia,Rafael Rosell, 来源:Cancer Biology & Medicine 年份:2015
Survival rates for metastatic lung cancer, including non-small cell lung cancer(NSCLC) and small cell lung cancer(SCLC), are poor with 5-year survivals of less...
[期刊论文] 作者:Cristina Teixidó,Niki Karachaliou,Vicente Peg,Ana Gimenez-Capitan,Rafael Rosell,魏建国,许春伟,张博,, 来源:临床与病理杂志 年份:2015
棘皮动物微管结合蛋白-间变性淋巴瘤激酶(echinoderm microtubule-associated prote i n-l ike4-anaplastic lymphoma kinase,EML4-ALK)在肺癌中已成为第二个最重要的驱动致...
[期刊论文] 作者:Alvarez,María González-Cao,Niki Karachaliou,Mariacarmela Santarpia,Santiago Viteri,Cristina Teixidó,Rafael Rosell, 来源:Cancer Biology & Medicine 年份:2015
Different approaches for treating lung cancer have been developed over time, including chemotherapy, radiotherapy and targeted therapies against activating muta...
[期刊论文] 作者:Wang,Yonghua Zhu,Jiao Chen,Yuhan Yang,Lingxia Zhu,Jiayu Zhao,Yang Yang,Xueting Cai,Chunping Hu,Rafael Rosell, 来源:药学学报(英文版) 年份:2020
Pancreatic cancer is one of the most aggressive cancers with poor prognosis and a low 5-year survival rate.The family of P21-activated kinases (PAKs) appears to...
[会议论文] 作者:Lixia Yu,Jose Javier Sanchez,Zhengyun Zou,Xiaoping Qian,Xia Sun,Ana Gimenez-Capitan,Wenxian Guan,Rafael Rosell, 来源:第十六届全国临床肿瘤学大会暨2013年CSCO学术年会 年份:2013
[会议论文] 作者:Lixia Yu,Jose Javier Sanchez,Zhengyun Zou,Xiaoping Qian,Xia Sun,Ana Gimenez-Capitan,Wenxian Guan,Rafael Rosell, 来源:2013医学前沿论坛暨第十三届全国肿瘤药理与化疗学术会议 年份:2013
[会议论文] 作者:Lixia Yu,Jose Javier Sanchez,Zhengyun Zou,Xiaoping Qian,Xia Sun,Ana Gimenez-Capitan,Wenxian Guan,Rafael Rosell, 来源:2013医学前沿论坛暨第十三届全国肿瘤药理与化疗学术会议 年份:2013
Background & Aims BRCA1 expression affects outcome to chemotherapy.In response DSBs,MDC1 binds to H2AX,promoting DSB repair by 53BP1 and BRCA1.MMSET is required for the accretion of 53BP1 and UBC9 to...
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