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[会议论文] 作者：Xiu-ying Yang,Bai-nian Chen,Ran-yao Yang,Guan-hua Du,
来源：The 5th China-Japan Joint Meeting of Basic andCl.inieal phar 年份：2011
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Effects of DL0410 on the learning and memory deficit in APP/PS1 transgenic Alzheimer′s disease model
[期刊论文] 作者：Rong YAN,Ran-yao YANG,Ai-lin LIU,Guan-hua DU,,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE DL0410,one novel compound discovered inhigh throughput screening(HTS),was found to be a potent inhibitor for AChE and BuChE.Memory deficit mice model...
[会议论文] 作者：Ran-yao YANG,Jian-song FANG,Ai-lin LIU,Guan-hua DU,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
Aim: Cdk5 is an a typical cyclin-dependent kinase localized in the brain, and its activity is dependent upon binding to p35.Cdk5/p35 plays an important role in the hyperphosphorylation of tau protein,...
Predictions of BuchE inhibitors using support vector machine (SVM) and naive Bayesian classification
[会议论文] 作者：Jian-song FANG,Ran-yao YANG,Ai-lin LIU,Guan-hua DU,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
Aim: Butyrylcholinesterases (BuChE, EC 3.1.1.8) is emerging as an important pharmacological target in Alzheimers disease (AD) therapy.Due to high cost and laboriousness in experimental tests, it is ne...
DL0410, a novel dual cholinesterase inhibitor,protects mouse brains against Aβ-induced neuronal dama
[期刊论文] 作者：Dan ZHOU,Wei ZHOU,Jun-ke SONG,Zhang-ying FENG,Ran-yao YANG,Song WU,Lin WANG,
来源：中国药理学报（英文版） 年份：2016
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