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Kinase deficient missense mutations of ATM display higher oncogenic potential than simple loss of AT
[会议论文] 作者:Jiguang Wang,Raul Rabadan,Brian Lee,Kenta Yamamoto,Denis Loredan,Shan Zha,Chen Li,Dong Wang,Jun Xu,
来源:The 16th Ataxia-Telangiectasia Workshop (ATW-2015)6th Intern 年份:2015
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Kinase deficient missense mutations of ATM display higher oncogenic potential than simple loss of AT
[会议论文] 作者:Kenta Yamamoto,Jiguang Wang,Jun Xu,Chen Li,Brian Lee,Denis Loredan,Dong Wang,Raul Rabadan,Shan Zha,
来源:The 16th Ataxia-Telangiectasia Workshop (ATW-2015)6th Intern 年份:2015
ATM kinase is a master regulator of DNA damage responses.Germline inactivation of ATM cause Ataxia-Telangiectasia (A-T) syndrome characterized by neuronal degeneration, immunodeficiency and greatly in...
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