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Improved EGFR mutation detection sensitivity after enrichment by Cas9/sgRNA digestion and PCR amplif
[期刊论文] 作者:Li Wang,Jing Jiang,Xiangning Li,Kai Li,Rongzhang He,Jia Li,Lili Duan,Weihao Luo,Zheng Hu,Dixian Luo,
来源:生物化学与生物物理学报(英文版) 年份:2020
The detection of circulating tumor DNA is important in cancer research and clinical practice.In the present study,we aimed to improve the sensitivity of downstr...
[期刊论文] 作者:Yuanqing Zeng,Jia Li,Wangyuan Guo,Weihao Luo,Xiangting Liu,Rongzhang He,Zheng Hu,Lili Duan,Chenglai Xia,
来源:生物化学与生物物理学报(英文版) 年份:2021
The cellular response to DNA damage is crucial for maintaining the integrity and stability of molecular structure.To maintain genome stability,DNA-damaged cells should be arrested so that mutations can be repaired before replication.Althoug......
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