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Roles of 5-HT2 receptors in effects of DOM,ketamine and methamphetamine on prepulse inhibition in Sp
[期刊论文] 作者:JIANG Kai-li,LI Kai-xi,LIU Xiao-yan,SU Rui-bin,
来源:中国药理学与毒理学杂志 年份:2021
OBJECTIVE Prepulse inhibition(PPI)of the acoustic startle response provides a measure of sensorimotor gating system mecha⁃nisms,which is known to be impaired in schizo⁃phrenia patients.We assessed the effects of the 5-HT2A/2C receptor ago......
[会议论文] 作者:YANG Yi,ZHOU Pei-lan,SU Rui-bin,GONG Ze-hui,
来源:第十七届全国神经精神药理学学术会议 年份:2016
OBJECTIVE To investigate the subtype(s)of α2-adrenoceptor(α2-AR)that mediated the sedation of mice.And demonstrate the influence of cAMP and G protein gated inwardly rectifying K+channels on the sedat...
[期刊论文] 作者:ZHANG Yi-xin,ZHOU Pei-lan,LU Feng-feng,SU Rui-bin,GONG Ze-hui,
来源:中国药理学与毒理学杂志 年份:2021
OBJECTIVE Chronic morphine exposure reduced analgesic efficiency leads to morphine tolerance which was mediated byβ-arrestin signaling of MOR,but the further mecha⁃nism remains unclear.METHODS AND RESULTS Morphine tolerance and dependence......
[期刊论文] 作者:WANG Na,LIAN Jing-jing,CAO Yan-qing,YU Gang,SU Rui-bin,
来源:中国药理学与毒理学杂志 年份:2021
OBJECTIVE To identify benzodi⁃azepine(BZD)effects that are insensitive to the classical BZD binding site antagonist,flumazenil.Whether the flumazenil-insensitive BZD effects have selectivity on different GABAA receptor sub⁃types was also ......
[会议论文] 作者:MA Hao,LI Fei,WU Ning,SU Rui-bin,LI Jin,
来源:第十五届中国神经精神药理学学术会议 年份:2012
OBJECTIVE To study the role of I1-Imidazoline receptor(I1R) in opioid dependence.METHODS Subcellular location of μ opioid receptor (MOR) and IRAS was investigated by immunocytochemistry.The interactio...
[会议论文] 作者:SUN Xue,LI Fei,WU Ning,SU Rui-bin,LI Jin,
来源:第十五届中国神经精神药理学学术会议 年份:2012
OBJECTIVCE Schizophrenia is a chronic, debili tating psychotic mental disorder.Many studies suggest that dopa mine D3 receptor (DAD3R) plays an important role in etioloy of schizophrenia, and selectiv...
[会议论文] 作者:MA Wen-tao,LIU Ke,GONG Ze-hui,YONG Zheng,SU Rui-bin,
来源:第十七届全国神经精神药理学学术会议 年份:2016
Impulse control disorders have been gradually associated with pramipexole therapy of Parkinson disease,and this has been confirmed in various rodent models of impulsivity,such as the delay-discounting...
Two new isoforms of IRAS/Nischarin may be inhibit cell proliferation and have no function of I1 R kn
[会议论文] 作者:ZHAO Tai-yun,WANG Bo,SU Rui-bin,WU Ning,CONG Yu-wen,LI Jin,
来源:中国药理学会第十一次全国学术会议 年份:2011
OBJECTIVE To research two novel I1R isoforms and explore its function, so as find its role in the pharmacological function of I1R.METHODS Based on the bioinformatics, combined with previous investigat...
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