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Andrographolide restores steroid sensitivity to block LPS/IFNγ-induced IL-27 and airway hyper-respon
[期刊论文] 作者：Wu-peng LIAO,Wan Shun Daniel TAN,Wai-Shiu Fred WONG,,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE Steroid-resistant airway hyper-responsiveness(AHR)has been proposed to be related to the activation of innate host defense pathways such as those indu...
Non-typeable haemophilus influenzae-induced exacerbation on a cigarette smoke lung injury model:Prot
[期刊论文] 作者：Daniel TAN,Hong-yon PEH,Chu-hui PANG,Wu-peng LIAO,Tze-khee CHAN,Suk-hiang LAU,Vincent T.K.CHOW,Wai-shiu Fred WONG,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE To develop a 2-week cigarette smoke(CS)acute lung injury model exacerbated by haemophilus influenzae(NTHi)and study the protective effect of andrograp...
Vitamin E isoform γ-tocotrienol alleviates cigarette smoke-induced chronic obstructive pulmonary dis
[期刊论文] 作者：Hong Yong PEH,Wan Shun Daniel TAN,Tze Khee CHAN,Chen Wei POW,Choon Nam ONG,Wai-Shiu Fred WONG,,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE Cigarette smoke-induced chronic obstructive pulmonary disease(COPD)is a leading cause of death,where inflammation and oxidative stress are involved in...
Anti-malarial drug,artesunate,as a novel therapeutic drug target for airway wall remodeling in asthm
[期刊论文] 作者：TAN,Benjamin ONG,Chang CHENG,Wanxing Eugene HO,John K.C TAM,Alastair G.STEWART,Trudi HARRIS,Wai-Shiu Fred WONG,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE Airway wall remodeling(AWR),which refers to structural changes in the airway,is a key characteristic of asthma.Airway smooth muscle(ASM)cell hypertrop...
[期刊论文] 作者：Yiqian GOH,Sreenivasa Rao SAGINEEDU,Audrey Chee Hui YONG,Shiran Mohd SIDIK,Nordin Haji LAJIS,Wai-Shiu Fred WONG,
来源：中国药理学与毒理学杂志 年份：2015
Andrographis paniculata contains two main diterpenoid constituents,andrographolide(AGP)and 14-deoxy-11,12-didehydroandrographolide(DDAG),which were found to exh...
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