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[期刊论文] 作者：Wolfgang Link,,
来源：World Journal of Biological Chemistry 年份：2012
The WNT/-catenin and phosphoinositide 3-kinase(PI3K/AKT) signaling cascades both have been implicated in the formation and progression of colorectal cancer.Onco...
Exploring the Biological Space of FOXO Transcription Factors:Discovery of Kinase Inhibitors for Anti
[会议论文] 作者：Wolfgang Link,
来源：BIT‘s2nd Annual World Cancer Congess-2009 (2009第二届癌症大会) 年份：2009
Many human tumors have activated the protein kinase Akt either by activation of the oncogene PI3Kα or by inactivation of the tumor suppressor PTEN.When activated, Akt phosphorylates and thereby inacti...
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