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SM02-P26:Design, Synthesis and Biological Evaluation of Flavonoid Derivatives as Cardiovascular Agen
[会议论文] 作者：Xiaowu Dong,Yongzhou Hu,
来源：第13届亚洲化学大会(13th Asian Chemical Congress) 年份：2009
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SM02-P26:Design, Synthesis and Biological Evaluation of Flavonoid Derivatives as Cardiovascular Agen
[会议论文] 作者：Xiaowu Dong,Yongzhou Hu,
来源：第13届亚洲化学大会(13th Asian Chemical Congress) 年份：2009
...
[会议论文] 作者：Ruiying Guo,Xiaowu Dong,Yongzhou Hu,
来源：2016年长三角药物化学研讨会 年份：2016
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Discovery of Novel JAK2 Inhibitors via Integration of Pharmacophore Mapping and Molecular Docking in
[会议论文] 作者：Xingguo Liu,Jinglai Huang,Xiaowu Dong,Yanping Huo,
来源：中国化学会第十三届全国有机合成化学学术研讨会 年份：2016
The JAK2 kinase has been proved to be critically involved in receptor signaling,and emerged as a leading therapeutic target for oncology1-2.In this study,we have attempted to discover novel scaffold o...
Construction of DOS library through transition metal catalyzed tandem reactions and its biological a
[会议论文] 作者：Can-Liang Ma,Yongzhou Hu,Youhong Hu,Xiaowu Dong,
来源：2016年长三角药物化学研讨会 年份：2016
A small molecules library with structure diversity was constructed through diversity-oriented synthesis (DOS) strategy.1 Seven novel scaffolds were quickly synthesized through transition metal catalyz...
Exploring Diphenylmethylamine Derivatives as Novel Akt1 Inhibitors:Design,Synthesis,Biological Evalu
[会议论文] 作者：Wenhu Zhan,Yanming Wang,Bo Yang,Yongzhou Hu,Xiaowu Dong,Tao Liu,
来源：全国药物化学学术会议暨第四届中英药物化学学术会议 年份：2013
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The Design, Synthesis and Biological Evaluation of Pro-EGCG Derivatives as Novel Anti-vitiligo Agent
[会议论文] 作者：Siyu Wang,Rong Jin,Ruiquan Wang,Yongzhou Hu,Xiaowu Dong,Aie Xu,
来源：2016年长三角药物化学研讨会 年份：2016
With aim to overcome the instability and poor membrane permeability of EGCG,1 a series of prodrugs of EGCG and its derivatives (Pro-EGCGs) were designed,synthesized,and biological evaluation for their...
[会议论文] 作者：Yewei Chen,Jianzhong Chen,Xiaowu Dong,Tao Liu,Lilin Du,Maotang sun,Yongzhou Hu,
来源：2009长三角药物化学研讨会 年份：2009
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SM02-P28:3,4-diaryl-5-aminoisoxazole and 4,5-diaryl-3-aminepyrazole derivatives as analogs of combre
[会议论文] 作者：Tao Liu,Xiaowu Dong,Chen Jing,Rui Wu,Qiaojun He,Bo Yang,Yongzhou Hu,ZJU-ENS,
来源：第13届亚洲化学大会(13th Asian Chemical Congress) 年份：2009
Microtubules represent an attractive target for antitumor drug discovery.Combretastatin A-4 (CA-4),a natural cis-stilbene product, strongly inhibits the tubulin assembly and prevents tubulin polymeriz...
[期刊论文] 作者：,Tao Yuan,Ruilin Wu,Chenxi Zhao,Jiao Wang,Jiabin Lu,Bo Zhang,Nengming Lin,Xin Dong,Xiaoyang Dai,Xiaowu Dong,
来源：药学学报（英文版） 年份：2021
Cholangiocarcinoma(CCA)has emerged as an intractable cancer with scanty therapeutic regimens.The aberrant activation of Yes-associated protein(YAP)and transcriptional co-activator with PDZ-binding motif(TAZ)are reported to be common in CCA ......
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