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,Isomer-selective distribution of 3-n-butylphthalide (NBP) hydroxylated metabolites, 3-hydroxy-NBP a
[期刊论文] 作者：Xing-xing DIAO,Kan ZHONG,Xiu-li LI,Da-fang ZHONG,Xiao-yan CHEN,
来源：中国药理学报（英文版） 年份：2015
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Furmonertinib(Alflutinib,AST2818)is a potential positive control drug comparable to rifampin for eva
[期刊论文] 作者：Ya-li Wu,Ya-ru Xue,Zi-tao Guo,Zhen-dong Chen,Xin-yu Ge,Da-fang Zhong,Xing-xing Diao,
来源：中国药理学报（英文版） 年份：2022
Furmonertinib(Alflutinib,AST2818),as a third-generation epidermal growth factor receptor inhibitor with an advanced efficacy and a relatively wide safety window,has been commercially launched in China recently.However,previous clinical stud......
[期刊论文] 作者：Xiao-yun Liu,Zi-tao Guo,Zhen-dong Chen,Yi-fan Zhang,Jia-lan Zhou,Yong Jiang,Qian-yu Zhao,Xing-xing Diao,
来源：中国药理学报（英文版） 年份：2020
Alflutinib (AST2818) is a third-generation epidermal growth factor receptor (EGFR) inhibitor that inhibits both EGFR-sensitive mutations and T790M mutations.Pre...
[期刊论文] 作者：Qian-qian Tian,Yun-ting Zhu,Xing-xing Diao,Xiang-lei Zhang,Ye-chun Xu,Xiang-rui Jiang,Jing-shan Shen,,
来源：中国药理学报（英文版） 年份：2021
TPN729 is a novel phosphodiesterase 5(PDE5)inhibitor used to treat erectile dysfunction in men.Our previous study shows that the plasma exposure of metabolite M...
Sulfation predominates the pharmacokinetics,metabolism,and excretion of forsythin in humans:major en
[期刊论文] 作者：Lu-lu Pan,Yong Yang,Min Hui,Shuo Wang,Cui-yun Li,Hong Zhang,Yan-hua Ding,Li Fu,Xing-xing Diao,Da-fang,
来源：中国药理学报（英文版） 年份：2021
Forsythin extracted from Forsythiae Fructus is widely used to treat fever caused by the common cold or influenza in China,Japan and Korea.The present study aime...
Pharmacokinetics,mass balance,and metabolism of[14C]vicagrel,a novel irreversible P2Y12 inhibitor in
[期刊论文] 作者：,Yong-qiang Liu,Yan-chun Gong,Xue-fang Liu,Hong-bin Sun,Yong-guo Li,Da-fang Zhong,Li-yan Miao,Xing-xing Diao,
来源：中国药理学报（英文版） 年份：2021
Vicagrel,a novel irreversible P2Y12 receptor inhibitor,is undergoing phase Ⅲ trials for the treatment of acute coronary syndromes in China.In this study,we evaluated the pharmacokinetics,mass balance,and metabolism of vicagrel in six healt......
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