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The role of ribosomal proteins in the regulation of cell proliferation, tumorigenesis, and genomic i
[期刊论文] 作者:Xilong Xu,Xiufang Xiong,Yi Sun,,
来源:Science China(Life Sciences) 年份:2016
Ribosomal proteins(RPs), the essential components of the ribosome, are a family of RNA-binding proteins, which play prime roles in ribosome biogenesis and prote...
[会议论文] 作者:Xiufang Xiong,Yongchao Zhao,Yi Sun,
来源:中国细胞生物学学会2015年全国学术大会 年份:2015
Cell-based studies showed that several Mdm2-binding ribosomal proteins, upon overexpression, stabilize and activate p53.In contrast, here we show in a mouse knockout study that Mdm2-binding ribosomal...
The role of ribosomal proteins in the regulation of cell proliferation, tumorigenesis, and genomic i
[期刊论文] 作者:Xilong Xu,Xiufang Xiong,Yi Sun,,
来源:Science China(Life Sciences) 年份:2016
Ribosomal proteins(RPs), the essential components of the ribosome, are a family of RNA-binding proteins, which play prime roles in ribosome biogenesis and protein translation. Recent studies revealed...
Discovery of a small molecule inhibitor of cullin neddylation that triggers ER stress to induce auto
[期刊论文] 作者:Yanan Li,Chaorong Wang,Tiantian Xu,Peichen Pan,Qing Yu,Lei Xu,Xiufang Xiong,Tingjun Hou,Sunliang Cui,,
来源:药学学报(英文版) 年份:2021
Protein neddylation is catalyzed by a three-enzyme cascade,namely an E1 NEDD8-activating enzyme(NAE),one of two E2 NEDD8 conjugation enzymes and one of several E3 NEDD8 ligases.The physiological substrates of neddylation are the family memb......
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