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[期刊论文] 作者：Xue-chu Zhen,Hong-Yuan Chu,
来源：中国药理学报（英文版） 年份：2020
Parkinsons disease (PD) is one of the most common neurodegenerative diseases.Genetic factors are involved in ＜10％ of PD cases,while the majority of PD cases have...
Ovarian hormone-dependent changes in cocaine-induced dopamine neuron activities that is associated w
[会议论文] 作者：Die ZHANG,Guo-Zhang JIN,Xue-Chu ZHEN,
来源：中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份：2007
Clinical and experimental evidences have indicated that females appear to be more vulnerable than males to the reinforcing effects of psychostimulants.Gender differences have been repeated demonstrate...
Dihydromyricetin protects neurons in an MPTP-induced model of Parkinson’s disease by suppressing gly
[期刊论文] 作者：Zhao-xiang REN,Ya-fei ZHAO,Ting CAO,Xue-chu ZHEN,
来源：中国药理学报（英文版） 年份：2016
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[会议论文] 作者：Chang-Liang LIU,Guo-Zhang JIN,Xiao-Hua CAO,Xue-Chu ZHEN,
来源：中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份：2011
Oscillatory firing is an important process in neural system for presenting, integrating and synchronizing neuronal signals.Though most pyramidal neurons are able to oscillate at a broad band, only a f...
,1-Stepholidine increases the frequency of sEPSC via the activation of D1 dopamine signaling pathway
[期刊论文] 作者：Ming GAO,Chang-liang LIU,Shen YANG,Xue-chu ZHEN,Guo-zhang JIN,
来源：中国药理学报（英文版） 年份：2007
Aim: To investigate the effect ofl-stepholidine (SPD) on the frequency of spon-taneous excitatory postsynaptic currents (sEPSC) in the pyramidal cells between l...
[期刊论文] 作者：Wei-hua GU,Shen YANG,Wei-xing SHI,Guo-zhang JIN,Xue-chu ZHEN,
来源：中国药理学报（英文版） 年份：2007
Aim: To elucidate the role of scaffold protein postsynaptic density (PSD)-95 in the dopamine D1 receptor (D1R)-modulated NR 1a/NR2B receptor response.Methods: T...
[期刊论文] 作者：Wei-hua GU,Shen YANG,Wei-xing SHI,Xue-chu ZHEN,Guo-zhang JIN,
来源：中国药理学报（英文版） 年份：2007
Aim: To examine whether (-)-stepholidine (SPD) has a direct effect on the N-methyl-D-aspartic acid receptors (NMDAR) containing the NMDA receptor sub-units NR2A...
[期刊论文] 作者：Shang-lin ZHOU,Hong-yuan CHU,Guo-zhang JIN,Jian-min CUI,Xue-chu ZHEN,
来源：中国药理学报（英文版） 年份：2014
...
,Protease Omi facilitates neurite outgrowth in mouse neuroblastoma N2a cells by cleaving transcripti
[期刊论文] 作者：Qi MA,Qing-song HU,Ran-jie XU,Xue-chu ZHEN,Guang-hui WANG,
来源：中国药理学报（英文版） 年份：2015
...
[会议论文] 作者：Xing FANG,Chang-Liang LIU,Qian-Qian Wu,Guo-Zhang JIN,Xue-Chu ZHEN,
来源：中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份：2011
The dopamine-containing neurons of the midbrain ventral tegmental area (VTA) play a critical role in the reinforcing effects of drugs of abuse.It has long been known that morphine can excite dopamine...
Development and characterization of an inducible Dicer conditional knockout mouse model of Parkinson
[期刊论文] 作者：Chen-hong Guo,Ting Cao,Long-tai Zheng,John L Waddington,Xue-chu Zhen,
来源：中国药理学报（英文版） 年份：2020
Parkinson’s disease (PD) is a common neurodegenerative disease characterized by motor impairment and progressive loss of dopamine (DA) neurons.At present,the a...
[会议论文] 作者：Pei-Hua SUN,Jing-Ru WANG,Wei-Hua GU,Jie ZHENG,Guo-Zhang JIN,Xue-Chu ZHEN,
来源：中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份：2007
PSD-95 is enriched in the postsynaptic density which has been shown to play an important role in the regulation of neurotransmitter receptor functions.The direct physical interaction between PSD-95 an...
,The oncometabolite 2-hydroxyglutarate inhibits microglial activation via the AMPK/mTOR/NF-κB pathwa
[期刊论文] 作者：Chao-jun Han,Ji-yue Zheng,Lin Sun,Hui-cui Yang,Zhong-qiang Cao,Xiao-hu Zhang,Long-tai Zheng,Xue-chu Zhen,
来源：中国药理学报（英文版） 年份：2019
Microglia,the brain-resident macrophage,is known as the innate immune cell type in the central nervous system.Microglia is also the major cellular component of...
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