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Antibacterial Activity of Maple Leaves Extracts and Their Inhibition to Bacterial β-ketoacyl-ACP Red
[会议论文] 作者：Dan Wu,Xuefu You,Xiaofeng Ma,Weixi Tian,Xiaodong Wu,
来源：2007 Enzyme Engineering Conference(国际酶工程学术会议) 年份：2007
Fatty acids are important component of cell membrane,whereas the distinct difference between mammalian and bacterial fatty acid synthase system making the l...
[会议论文] 作者：Hao Wang,Yuzhen wei,Hongyu Liu,Yuqing Zhang,Xuefu You,Liyan Yu,
来源：The 13th International Conference on Culture Collections(ICC 年份：2013
Vancomycin group compounds belong to the glycopeptide class of antibiotics, which are synthesized by non-ribosomal peptide synthetase (NRPS), produced exclusively by actinomycetes.Vancomycin is clinic...
,Hypericin enhances β-lactam antibiotics activity by inhibiting sarA expression in methicillin-resis
[期刊论文] 作者：Genzhu Wang,Liang Li,Xiukun Wang,Xue Li,Youwen Zhang,Jie Yu,Jiandong Jiang,Xuefu You,Yan Q.Xiong,
来源：药学学报（英文版） 年份：2019
Bacteremia is a life-threating syndrome often caused by methicillin-resistant Staphylococcus aureus (MRSA).Thus,there is an urgent need to develop novel approac...
Validated LC–MS/MS method for determination of YH-8, a novel PKnB inhibitor, in rat plasma and its a
[期刊论文] 作者：Qianqian Zhai,Jing Pang,Guoqing Li,Congran Li,Xinyi Yang,Liyan Yu,Yucheng Wang,Jian Li,Xuefu You,,
来源：Acta Pharmaceutica Sinica B 年份：2015
(E)-Methyl-4-aryl-4-oxabut-2-enoate(YH-8) is a novel PKn B protein kinase inhibitor with good anti-tuberculosis activity. To evaluate its pharmacokinetics in ra...
[会议论文] 作者：Ningyu Zhu,Yuan Lin,Dongsheng Li,Nana Gao,Chang Liu,Xuefu You,Jiandong Jiang,Wei Jiang,Shuyi Si,
来源：第八届国际分子模拟与信息技术应用学术会议 年份：2016
Objectives: Drug-resistant Mycobacterium tuberculosis poses a great threat to human health.Tyrosyl-tRNA synthetase(TyrRS)is one of the aminoacyl tRNA synthetases that catalyse the attachment of amino...
Cyclic and Linear Thiopeptides from Soil-Derived Streptomyces sp.CPCC 203702 with Antiviral and Anti
[期刊论文] 作者：Dewu Zhang,Yujia Wang,Xinxin Hu,Xiaoyu Wang,Linzi Li,Guowei Gu,Bingyuan Zhang,Shan Cen,Xuefu You,Liyan,
来源：中国化学（英文版） 年份：2021
A new cyclic thiopeptide,berninamycin F (3),three new linear thiopeptides,berninamycins G—I (4-6),and two known berninamycin derivatives,berninamycins C and D (1 and 2) were isolated from Streptomyces sp.CPCC 203702.Their structures were e......
,In vitro and in vivo activity of D-serine in combination with β-lactam antibiotics against methicil
[期刊论文] 作者：Xue Li,Xi Lu,Xiukun Wang,Xinxin Hu,Tongying Nie,Xinyi Yang,Yan Q.Xiong,Jiandong Jiang,Congran Li,Xuefu You,
来源：药学学报（英文版） 年份：2019
As D-amino acids play important roles in the physiological metabolism of bacteria,combination of D-amino acids with antibiotics may provide synergistic antibact...
Diversity,novelty,antimicrobial activity,and new antibiotics of cultivable endophytic actinobacteria
[期刊论文] 作者：Liu,Xugela Habden,Elizaveta A.Razumova,Ilya A.Osterman,Petr V.Sergiev,Olga A.Dontsova,Xinxin Hu,Xuefu You,
来源：药物分析学报（英文版） 年份：2021
Three hundred and twenty endophytic actinobacterial strains were isolated from psammophytes collected from Taklamakan Desert and identified.Among them,three str...
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