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[期刊论文] 作者：Ke Li,Li Li,Ye-Chun Xu,,
来源：Nuclear Science and Techniques 年份：2017
Beta-ketoacyl-acyl-carrier-protein synthase II，在细菌的丰满的酸的生合成的重要的酶，是在抗菌剂药设计的一个吸引人的目标。Platensimycin (PTM ) ，由 Streptomyces platens...
Iron dysregulates APP processing accompanying with sAPPα cellular retention and β-secretase inhibiti
[期刊论文] 作者：Yu-ting CHEN,Wu-yan CHEN,Xiao-tian HUANG,Ye-chun XU,Hai-yan ZHANG,
来源：中国药理学报（英文版） 年份：2018
Amyloid precursor protein (APP) and iron both play pivotal roles in the central nervous system,but whether and how iron influences the processing of endogenous...
Microsecond molecular dynamics simulation of Aβ42 and identification of a novel dual inhibitor of ag
[期刊论文] 作者：Yuan-yuan WANG,Li LI,Tian-tian CHEN,Wu-yan CHEN,Ye-chun XU,
来源：中国药理学报（英文版） 年份：2013
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,Paeoniflorin ameliorates ischemic neuronal damage in vitro via adenosine A1 receptor-mediated trans
[期刊论文] 作者：Min ZHONG,Wan-ling SONG,Ye-chun XU,Yang YE,Lin-yin FENG,
来源：中国药理学报（英文版） 年份：2015
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[期刊论文] 作者：Yun-jun Ge,Qi-wen Liao,Ye-chun Xu,Qiang Zhao,Bei-li Wu,Richard D.Ye,
来源：中国药理学报（英文版） 年份：2020
G protein-coupled receptors (GPCRs) play important roles in human physiology.GPCRs are involved in immunoregulation including regulation of the inflammatory res...
L655,240, acting as a competitive BACE1 inhibitor,efficiently decreases β-amyloid peptide production
[期刊论文] 作者：Qin LU,Wu-yan CHEN,Zhi-yuan ZHU,Jing CHEN,Ye-chun XU,Morakot KAEWPET,Vatcharin RUKACHAISIRIKUL,Li-li,
来源：中国药理学报（英文版） 年份：2012
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[期刊论文] 作者：Qian-qian Tian,Yun-ting Zhu,Xing-xing Diao,Xiang-lei Zhang,Ye-chun Xu,Xiang-rui Jiang,Jing-shan Shen,,
来源：中国药理学报（英文版） 年份：2021
TPN729 is a novel phosphodiesterase 5(PDE5)inhibitor used to treat erectile dysfunction in men.Our previous study shows that the plasma exposure of metabolite M...
[期刊论文] 作者：Peng-xuan Ren,Wei-juan Shang,Wan-chao Yin,Huan Ge,Lin Wang,Xiang-lei Zhang,Bing-qian Li,Hong-lin Li,Ye-chun Xu,
来源：中国药理学报（英文版） 年份：2022
The COVID-19,caused by SARS-CoV-2,is threatening public health,and there is no effective treatment.In this study,we have implemented a multi-targeted anti-viral drug design strategy to discover highly potent SARS-CoV-2 inhibitors,which simu......
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