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MiR-21 down-regulation mediates Glioblastoma Cancer Stem Cells Proliferation and Apoptosis by target
[会议论文] 作者:Chao Shang,Yi-Xue Xue,
来源:第一届辽宁省神经科学学会学术研讨会 年份:2014
Objectives: To investigate whether the miR-21 could down-regulate FASLG to regulate the proliferation and apoptosis in glioblastoma cancer stem cells(GSCs).Methods: Real-Time quantitative PCR was appl...
[会议论文] 作者:Teng Ma,Yi-xue Xue,
来源:The 6th FAONS Congress and 11th Biennial Conference of CNS(第 年份:2015
The purposes of this study were to investigate the potential roles of miR-200b in regulating RMP7-induced an increase in blood-tumor barrier(BTB)permeability and its possible molecular mechanisms.Micr...
Bradykinin down-regulating the expression levels of ZO-1, occludin and disrupting actin cytoskeleton
[会议论文] 作者:Li-Bo LIU,Yi-Xue XUE,
来源:中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份:2007
Objective Tight junction (TJ) is an important structural and functional basis of maintaining blood-brain barrier (BBB) integrity.Bradykinin (BK) has been shown to selectively open blood-tumor barrier...
[会议论文] 作者:Chao Shang,Yi-xue Xue,
来源:The 6th FAONS Congress and 11th Biennial Conference of CNS(第 年份:2015
Objective This study was to determine the regulation effect of miR-143 to MACC1 gene and the influence of MACC1 gene on chemotherapy sensitivity in human U251 glioblastoma cells.Methods The expression...
Roles of protein kinase C and RhoA in the opening of blood-tumor barrier induced by low-dose endothe
[会议论文] 作者:Li-Bo LIU,Li ZHEN,Yun-Hui LIU,Yi-Xue XUE,
来源:中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份:2011
Objective This study was performed with an in vitro blood-tumor barrier (BTB) model to investigate whether protein kinase C (PKC) and RhoA are involved in the low-dose endothelial monocyte-activating...
[会议论文] 作者:Ping Wang,Yi-Long Yao,Jun Ma,Yi-Xue Xue,
来源:The 6th FAONS Congress and 11th Biennial Conference of CNS(第 年份:2015
Objective Long non-coding RNAs(lncRNAs)are aberrantly expressed in many diseases including cancer.LncRNA CASC2(cancer susceptibility candidate 2)has been characterized as a tumor suppressor in endomet...
Endothelial-monocyte-activating polypeptide Ⅱ induces rat C6 glioma cell apoptosis through mitochond
[会议论文] 作者:Li-Bo LIU,Hui XIE,Yi-Xue XUE,Yun-Hui LIU,Zhen LI,Ping WANG,
来源:第一届辽宁省神经科学学会学术研讨会 年份:2014
Objective Endothelial-monocyte-activating polypeptide Ⅱ(EMAP Ⅱ)has been shown to inhibit tumors by targeting vascular endothelium.However,the effect of EM...
[期刊论文] 作者:Xin He,Wei Yuan,Chun-Qing Yang,Lu Zhu,Fei Liu,Juan Feng,Yi-Xue Xue,
来源:中国神经再生研究(英文版) 年份:2022
Ghrelin is a neuropeptide that has various physiological functions and has been demonstrated to be neuroprotective in a number of neurological disease models. However, the underlying mechanisms of ghrelin in Parkinson\'s disease remain larg......
[会议论文] 作者:Li-Bo Liu,Xiao-Bai Liu,Jun Ma,Yun-Hui Liu,Zhi-Qing Li,Teng Ma,Xi-He Zhao,Zhuo Xi,Yi-Xue Xue,
来源:The 6th FAONS Congress and 11th Biennial Conference of CNS(第 年份:2015
We have demonstrated that bradykinin(BK)could increase the permeability of blood-tumor barrier(BTB)via down-regulating the protein expressions of tight junction(TJ)associated protein claudin-5 and occ...
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