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The use of miR122 and its target sequence in adeno-associated virus-mediated trichosanthin gene ther
[期刊论文] 作者:Gai Ran,Xi-lin Feng,Yi-lin Xie,Qing-yun Zheng,Peng-peng Guo,Ming Yang,Ying-lu Feng,Chen Ling,Li-qing,
来源:结合医学学报(英文版) 年份:2021
Objective:Plant-derived cytotoxic transgene expression,such as trichosanthin (tcs),regulated by recom-binant adeno-associated virus (rAAV) vector is a promising cancer gene therapy.However,the cytotoxic transgene can hamper the vector produ......
Prevalence of neutralizing antibodies against liver-tropic adeno-associated virus serotype vectors i
[期刊论文] 作者:Chen Ling,Yuan Wang,Ying-lu Feng,Ya-ni Zhang,Jun Li,Xin-rui Hu,Li-na Wang,Mao-feng Zhong,Xiao-feng Zhai,
来源:结合医学学报(英文版) 年份:2015
Recombinant adeno-associated virus (rAAV) serotype 2, 3 and 8 vectors are the most promising liver-tropic AAV serotype vectors. Liver diseases are signiifcant p...
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