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Discovery of a Novel Structural Series of 1,2,5-triaryl Carboxpyrroles as p53/MDM2 Binding Inhibitor
[会议论文] 作者:Xiaodong Ma,Yongzhou Hu,
来源:全国药物化学学术会议暨第四届中英药物化学学术会议 年份:2013
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SM02-P26:Design, Synthesis and Biological Evaluation of Flavonoid Derivatives as Cardiovascular Agen
[会议论文] 作者:Xiaowu Dong,Yongzhou Hu,
来源:第13届亚洲化学大会(13th Asian Chemical Congress) 年份:2009
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[会议论文] 作者:Li Wang,Yongzhou Hu,
来源:2009长三角药物化学研讨会 年份:2009
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[会议论文] 作者:Jingying Yan,Yongzhou Hu,
来源:2009长三角药物化学研讨会 年份:2009
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SM02-P26:Design, Synthesis and Biological Evaluation of Flavonoid Derivatives as Cardiovascular Agen
[会议论文] 作者:Xiaowu Dong,Yongzhou Hu,
来源:第13届亚洲化学大会(13th Asian Chemical Congress) 年份:2009
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Discovery of a Novel Structural Series of 1,2,5-triaryl Carboxpyrroles as p53/MDM2 Binding Inhibitor
[会议论文] 作者:Xiaodong Ma,Yongzhou Hu,
来源:全国药物化学学术会议暨第四届中英药物化学学术会议 年份:2013
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[会议论文] 作者:Weisi Wang,Jianzhong Chen,Yongzhou Hu,
来源:2009长三角药物化学研讨会 年份:2009
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Design,synthesis and biological evaluation of 1-phenylpyridin-4-one derivatives as potential multita
[会议论文] 作者:Li Tang,Rong Sheng,Yongzhou Hu,
来源:全国药物化学学术会议暨第四届中英药物化学学术会议 年份:2013
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[会议论文] 作者:Pinrao Song,Tao Liu,Yongzhou Hu,
来源:2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份:2015
Checkpoint kinase 1(Chk1)represents an attractive target for anticancer therapy and the development of small molecule Chk1 inhibitors has delivered new strategies for enhancement of traditional DNA-da...
[会议论文] 作者:Maotang Sun,Tao Liu,Yongzhou Hu,
来源:2009长三角药物化学研讨会 年份:2009
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Design,Synthesis and Evaluation of Analogs of Initiation Factor 4E(elF4E)Cap-Binding Antagonist Bn7-
[会议论文] 作者:Chunqi Hu,Carston R.Wagner,Yongzhou Hu,
来源:2009长三角药物化学研讨会 年份:2009
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[会议论文] 作者:Minkui Zhang,Yongzhou Hu,Rong Sheng,
来源:2016年长三角药物化学研讨会 年份:2016
Microglia,the resident phagocytes of the CNS,plays an important role in the active immune defense and the progression of neuroinflammation.It is reported that inhibition of microglial activation contr...
[会议论文] 作者:Daqiang li,Tao liu,Yongzhou Hu,
来源:2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份:2015
Carfilzomib,a structural analogue derived from natural product epoxomicin that wasapproved by US FDA for the treatment of relapsed and refractory multiple myeloma[1-3]....
[会议论文] 作者:Li Tang,Rong Sheng,Yongzhou Hu,
来源:2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份:2015
A new series of multitarget-directed edaravone derivatives were designed and synthesized.Rational pharmcophore-directed design strategy was undertaken and antioxidant edaravone was combined with the a...
[会议论文] 作者:Pinrao Song,Yongzhou Hu,Tao Liu,
来源:第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 年份:2012
Checkpoint kinase 1(Chk1) is a Ser/Thr kinase that is involved in mediating the cellular response to DNA-damage.Inhibition of Chkl has been shown to abrogate DNA damage induced cell cycle arrest,allow...
Pharmacophore Model Construction of p53-MDM2 Binding Inhibitors and its Application in the Discovery
[会议论文] 作者:Weisi Wang,Xin Li,Yongzhou Hu,
来源:第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 年份:2012
Previous research has indicated that suppressing the tumor cells by inhibiting the binding of MDM2 to p53 with chemical compounds is a worthy endeavor as a new therapeutic strategy for cancer.In hope...
[会议论文] 作者:Ruiying Guo,Xiaowu Dong,Yongzhou Hu,
来源:2016年长三角药物化学研讨会 年份:2016
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Design,synthesis and biological evaluation of 1-phenylpyridin-4-one derivatives as potential multita
[会议论文] 作者:Li Tang,Rong Sheng,Yongzhou Hu,
来源:全国药物化学学术会议暨第四届中英药物化学学术会议 年份:2013
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[会议论文] 作者:Ling Zhang,Qing Xia,Yongzhou Hu,Rong Sheng,
来源:2009长三角药物化学研讨会 年份:2009
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[会议论文] 作者:Qing Ye,Dan Lv,MaoTang Sun,YongZhou Hu,
来源:第13届亚洲化学大会(13th Asian Chemical Congress) 年份:2009
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