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Design and synthesis of novel antifungal triazole derivatives with good activity and water solubilit
[期刊论文] 作者：Xu-Feng Cao,Wen-Jing Chu,Yong-Bing Cao,Yu-She Yang,,
来源：Chinese Chemical Letters 年份：2013
In order to find novel antifungal agents with good activity and aqueous solubility,a series of SYN-2869 analogues containing a pyridine ring were synthesized an...
[期刊论文] 作者：Ying WANG,Yu-she YANG,Xi-can TANG,Hai-yan ZHANG,
来源：中国药理学报（英文版） 年份：2011
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[期刊论文] 作者：Jing Huang,Bin Guo,Wen-Jing Chu,Xin Xie,Yu-She Yang,Xian-Li Zhou,,
来源：Chinese Chemical Letters 年份：2016
GPR40 has emerged as an attractive drug target for the treatment of type 2 diabetes due to its role in the enhancement of insulin secretion with glucose depende...
Synthesis,pharmacokinetics and in vivo antifungal activity of the novel water-soluble prodrugs of it
[期刊论文] 作者：Yu Liu,Xu-Feng Cao,Xin Liu,Yong-Bing Cao,Wen-Jing Chu,Yu-She Yang,,
来源：Chinese Chemical Letters 年份：2013
To improve the aqueous solubility of an itraconazole analogue,compound 1(YL-24),a series of novel prodrugs were synthesized.Among these prodrugs,the phosphate d...
[期刊论文] 作者：Hao-shu WU,Juan-hong YU,Ying-yin LI,Yu-she YANG,Qiao-jun HE,Yi-jia LOU,Ru-yun JI,
来源：中国药理学报（英文版） 年份：2007
Aim: To examine the insulin sensitizing effects of a novel α-methyl-α-phenoxylpropionate derivative YY20 in insulin-sensitive cell lines. Methods: The peroxis...
[期刊论文] 作者：Xi HU,Ying FENG,Yu SHEN,Xiao-feng ZHAO,Juan-hong YU,Yu-she YANG,Ying LENG,
来源：中国药理学报（英文版） 年份：2006
Aim: To study whether T33, a new synthesized non-thiazolidinedione (TZD) peroxisome proliferator-activated receptor (PPAR) γ/α dual agonist has an antidiabeti...
Design and synthesis of novel triazole derivatives containing γ-lactam as potential antifungal agent
[期刊论文] 作者：Yuan-Yuan Xu,An-Ran Qian,Xu-Feng Cao,Chen-Yu Ling,Yong-Bing Cao,Rui-Lian Wang,Yi-Su Li,Yu-She Yang,,
来源：Chinese Chemical Letters 年份：2016
A series of novel triazole derivatives containing γ-lactam were designed and synthesized, and their structures were confirmed by ~1H NMR,~(13)CNMR and HRMS. Th...
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