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Study of acylhydrazone derivatives with deoxygenated seven-membered rings as potential β-ketoacyl-ac
[会议论文] 作者：Yang Zhou,Yin Luo,Yu-Shun Yang,Liang Lu,Hai-Liang Zhu,
来源：第九届国际分子模拟与信息技术应用学术会议(ICMS&I2018) 年份：2018
Fatty acid biosynthesis is essential for bacterial survival.FabH,β-ketoacyl-acyl carrier protein (ACP) synthase III,is a particularly attractive target,since i...
Study of acylhydrazone derivatives with deoxygenated seven-membered rings as potential β-ketoacyl-ac
[会议论文] 作者：Yang Zhou,Yin Luo,Yu-Shun Yang,Liang Lu,Hai-Liang Zhu,
来源：第九届国际分子模拟与信息技术应用学术会议(ICMS&I2018) 年份：2018
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Modification,Biological Evaluation and 3D QSAR Studies of Novel 2-(1,3-Diaryl-4,5-Dihydro-1 H-Pyrazo
[会议论文] 作者：Yu-Shun Yang,Fei Zhang,Dan-Jie Tang,Yong-Hua Yang,Hai-Liang Zhu,
来源：第八届国际分子模拟与信息技术应用学术会议 年份：2016
A series of novel 2-(1,3-diaryl-4,5-dihydro-1H-pyrazol-5-yl)phenol derivatives(C1-C24)have been synthesized.The B-Raf inhibitory activity and anti-proliferation activity of these compounds have been t...
Study of acylhydrazone derivatives with deoxygenated seven-membered rings as potential β-ketoacyl-ac
[会议论文] 作者：Yang Zhou,Yin Luo,Yu-Shun Yang,Liang Lu,Hai-Liang Zhu,
来源：第八届国际分子模拟与信息技术应用学术会议 年份：2016
Fatty actci biosynthesis is essential for bacterial survival.FabH,β-ketoacyl-acyl carrier protein(ACP)synthase Ⅲ,is a particularly attractive target,since it is central to the initiation of fatty acid...
Synthesis,molecular modeling and biological evaluation of cinnamic acid derivatives with pyrazole mo
[会议论文] 作者：Wei-Ming Zhang,Man Xing,Ting-Ting Zhao,Yu-Jia Ren,Xian-Hui Yang,Yu-Shun Yang,Peng-Cheng Lv,Hai-Liang,
来源：第八届国际分子模拟与信息技术应用学术会议 年份：2016
A series of pyrazole derivatives(1e-30e)has been designed and synthesized,and their biological activities were evaluated for EGFR and HER-2 inhibition and tumor cell antiproliferation.Among the compou...
[期刊论文] 作者：Muhammad Abbas,Mirza Muhammad Faran Ashraf Baig,Yaliang Zhang,Yu-Shun Yang,Songyu Wu,Yiqiao Hu,Zhong-Chang,
来源：药物分析学报:英文版 年份：2021
The study aimed to achieve enhanced targeted cytotoxicity and cell-internalization of cisplatin-loaded deoxyribonucleic acid-nanothread(CPT-DNA-NT),mediated by scavenger receptors into HeLa cells.DNA-NT was developed with stiff-topology uti......
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