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FGFR/RACK1 interacts with MDM2, promotes P53 degradation, and inhibits cell senescence in lung squam
[期刊论文] 作者：Tao Chen,Fei Wang,Shupei Wei,Yingjie Nie,Xiaotao Zheng,Yu Deng,Xubin Zhu,Yuezhen Deng,Nanshan Zhong,Chengzhi,
来源：癌症生物学与医学:英文版 年份：2021
Objective:FGFR is considered an important driver gene of lung squamous cell carcinoma(LSCC).Thus,identification of the biological events downstream of FGFR is important for the treatment of this malignancy.Our previous study has shown that ......
CDK11 negatively regulates Wnt/β-catenin signaling in the endosomal compartment by affecting microtu
[期刊论文] 作者：Danmin Ou,Lin Chen,Jiang He,Zhuoxian Rong,Jie Gao,Zhi Li,Liyu Liu,Feiyu Tang,Jiang Li,Yuezhen Deng,Lunquan,
来源：癌症生物学与医学（英文版） 年份：2020
Objectives: Improper activation of Wnt/β-catenin signaling has been implicated in human diseases. Beyond the well-studied glycogen synthase kinase 3β (GSK3β)...
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