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[期刊论文] 作者:Yuwen Ke, Yanan Xu, Xuepeng Ch,
来源:科学新闻 年份:2004
文章简介染色体高级结构在调控基因表达中发挥非常重要的作用。此前对于哺乳动物胚胎发育过程中染色体三维结构动态变化了解有限。课题组使用优化后的少量细胞Hi-C方法建...
[期刊论文] 作者:Qi Fei,Hongyu Zhang,Lili Fu,Xinlan Dai,Baomei Gao,Min Ni,Chao Ge,Jinjun Li,Xia Ding,Yuwen Ke,Xuebiao,
来源:生物化学与生物物理学报(英文版) 年份:2008
To improve the efficacy of gene therapy for cancer, we designed four hammerhead ribozyme adenoviruses (R1 to R4) targeting the exposed regions of survivin mRNA....
[期刊论文] 作者:Guoqiang Li,Yang Yu,Yong Fan,Congru Li,Xiaocui Xu,Jialei Duan,Rong Li,Xiangjin Kang,Xin Ma,Xuepeng Chen,Yuwen Ke,
来源:Journal of Genetics and Genomics 年份:2017
Proper reprogramming of parental DNA methylomes is essential for mammalian embryonic development.However,it is unknown whether abnormal methylome reprogramming...
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