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[会议论文] 作者:Zhen Xi, 来源:第七届全国化学生物学学术会议 年份:2011
  Genome-wide RNAi screening has become a powerful tool for dissecting individual gene function and identifying genes involved in conferring complex phenotype...
[会议论文] 作者:Zhen Xi, 来源:第17届国际磷化学学术会议(The 17th International Conference on Phosphoru 年份:2007
[会议论文] 作者:Zhen Xi, 来源:第六届岭南有机化学论坛 年份:2016
[会议论文] 作者:Zhen Xi, 来源:中国化学会第十届全国化学生物学学术会议 年份:2017
CRISPR/Cas9 is a newly-developed technology for gene intervention,which relies on a single guide strand called sgRNA to exhibit its DNA cleavage activity....
[会议论文] 作者:Dejun Ma,Zhen Xi, 来源:第五届中国小核酸技术与应用学术会议 年份:2015
  The strategy of virus-induced gene silencing(VIGS)is commonly used to introduce dsRNAs to silence any desired gene in host plants[1].Although most VIGS-deri...
[会议论文] 作者:Chao Wei,Zhen Xi, 来源:第五届中国小核酸技术与应用学术会议 年份:2015
  Synthetic small interfering RNAs(siRNAs)can inhibit expression of disease-causing genes through post-transcriptional gene silencing mediated by the endogeno...
[会议论文] 作者:Longhuai Cheng,Zhen Xi, 来源:第五届中国小核酸技术与应用学术会议 年份:2015
  RNA interference is a powerful tool that allows the sequence-specific suppression of gene expression by small interfering RNAs(siRNAs).The major obstacle pr...
[会议论文] 作者:ShanShan Chen,Zhen Xi, 来源:第五届中国小核酸技术与应用学术会议 年份:2015
  RNA interference is a common physiological processes in mammalian cells in post transcriptional regulation of gene expression levels.21-25nt small interferi...
[期刊论文] 作者:Jiangcun WEI,Zujie QIN,Zhen XI, 来源:药用植物研究(英文版) 年份:2019
[Objectives] This study aimed to investigate the hypolipidemic effects of different processed products of Ilex hainanensis Merr to provide experimental basis fo...
[期刊论文] 作者:Jiangcun WEI,Yong CHEN,Zhen XI, 来源:药用植物研究(英文版) 年份:2018
[Objectives]To study the differences in the effects of Rheum officinale and wine prepared Rheum palmatum Dachengqi Decoction(DCQ)on laxative effect of mice.[Met...
[期刊论文] 作者:Su-yu Zhu Yuan Yuan Zhen Xi, 来源:临床肿瘤与癌症研究:英文版 年份:2012
Radiation recall phenomenon is a tissue reaction that develops throughout a previously irradiated area,precipitated by the administration of certain drugs.R...
[会议论文] 作者:Xiaoping Zhou,Zhen Xi,Chuanzheng Zhou, 来源:第五届中国小核酸技术与应用学术会议 年份:2015
  C4-AP is known to disrupt replication in E.coli and is a substrate for base excision repair[1][2].C4-AP is a major component of DNA damage produced by the a...
[期刊论文] 作者:Su-yu Zhu,Yuan Yuan,Zhen Xi,, 来源:Cancer Biology & Medicine 年份:2012
Radiation recall phenomenon is a tissue reaction that develops throughout a previously irradiated area,precipitated by the administration of certain drugs.Radia...
[期刊论文] 作者:Mengtian Ren,Jing Bai,Zhen Xi,, 来源:中国科学:化学英文版 年份:2019
Eukaryotic genomic DNA is packed into chromatin, whose fundamental structural unit is the nucleosome. As DNA-histone protein complexes, nucleosomes show differe...
[会议论文] 作者:Ismail Ismail,Wang Dawei,Zhen Xi, 来源:中国化学会第十届全国化学生物学学术会议 年份:2017
  Hydrogen sulfide(H2S),which is well known for its unpleasant smell and commonly apperceived as a poisonous gas,recently nominated as an important endogenous...
[会议论文] 作者:Qian Li,Dawei Wang,Zhen Xi, 来源:中国化学会第十届全国化学生物学学术会议 年份:2017
  Protoporphyrinogen Oxidase(PPO)is the penultimate enzyme in the biosynthesis of chlorophyll and heme,catalyzes the conversion of protoporphyinogen Ⅸ to pro...
[会议论文] 作者:Longhuai Cheng,Dejun Ma,Zhen Xi, 来源:中国化学会第十届全国化学生物学学术会议 年份:2017
Gene therapy is a promising strategy for the treatment of many gene related diseases.A safe and efficient gene delivery vector is always the first key step for the development of gene medicine....
[会议论文] 作者:Chao Yang,Dongli Liu,Zhen Xi, 来源:中国化学会第十届全国化学生物学学术会议 年份:2017
Synthetic small interfering RNAs(siRNAs)can inhibit expression of disease-causing genes through post-transcriptional gene silencing mediated by the endogenous RNA interference(RNAi)pathway[1]....
[会议论文] 作者:Chuanlin Wang,Zhenghua Wang,Zhen Xi, 来源:中国化学会第十届全国化学生物学学术会议 年份:2017
Cyclic dinucleotides(CDNs)play key roles as second messengers and signaling molecules in bacteria and metazoans....
[会议论文] 作者:Chaochao Fan,Zhen Xi,Chuanzheng Zhou, 来源:第十一届全国化学生物学学术会议 年份:2019
C4′-modified ribonucleotides have recently attracted great interests.[1] C4′ modifications introduce stereoelectronic effect and thus modulate the conformation of the ribose,without losing the 2′-OH....
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