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[期刊论文] 作者：Shi-Ping Zhu,Wen-Ya Wang,Kun Fang,Zheng-Gang Li,Guo-Qiang Dong,Zhen-Yuan Miao,Jian-Zhong Yao,Wan-Nian,
来源：Chinese Chemical Letters 年份：2014
The incidence of invasive fungal infections is increasing rapidly.Clinically available antifungal agents suffer from limited efficacy and severe resistance.Ther...
[期刊论文] 作者：Wei-Huang Zhou,Xi-Guo Xu,Jin Li,Xiao Min,Jian-Zhong Yao,Guo-Qiang Dong,Chun-Lin Zhuang,Zhen-Yuan Miao,
来源：Chinese Chemical Letters 年份：2017
In the past decade,the p53-MDM2 protein-protein interaction by small molecules has been confirmed as a successful strategy for cancer therapy.In our previous wo...
Amino acid derivatives of pyropheophorbide-a ethers as photosensitizer: Synthesis and photodynamic a
[期刊论文] 作者：Zhi Meng,Bin Shan,Ling Zhang,Gui-Yan Han,Ming-Hui Liu,Ning-Yang Jia,Zhen-Yuan Miao,Wan-Nian Zhang,Chun-Quan,
来源：Chinese Chemical Letters 年份：2016
Ten new water-soluble amino acid conjugates of pyropheophorbide-a ethers 4a–4j were synthesized and investigated for their in vitro photodynamic antitumor acti...
Design, synthesis and biological evaluation of E-ring modified evodiamine derivatives as novel antit
[期刊论文] 作者：Kun Fang,Guo-Qiang Dong,Hai Gong,Na Liu,Zhen-Gang Li,Shi-Ping Zhu,Zhen-Yuan Miao,Jian-Zhong Yao,Wan-Nian,
来源：Chinese Chemical Letters 年份：2014
A series of novel E-ring modified evodiamine derivatives were designed and synthesized as antitumor agents. Their capacity to interfere with the catalytic activ...
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