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[会议论文] 作者:Zheng-Hong Qin,
来源:The 6th FAONS Congress and 11th Biennial Conference of CNS(第 年份:2015
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Animal models of Huntington’s disease: implications in uncovering pathogenic mechanisms and developi
[期刊论文] 作者:Lin-hui WANG,Zheng-hong QIN,
来源:中国药理学报(英文版) 年份:2006
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder, which is caused by an abnormal expansion of Cytosine Adenine Guanine (CAG) trinu...
[期刊论文] 作者:Yan WANG,Zheng-hong QIN,
来源:中国药理学报(英文版) 年份:2013
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[期刊论文] 作者:Rui SHENG,Zheng-hong QIN,
来源:中国药理学报(英文版) 年份:2015
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[期刊论文] 作者:Wei-dong LE,Zheng-hong QIN,
来源:中国药理学报(英文版) 年份:2013
The word autophagy is derived from the Greek roots "auto"(self) and "phagy" (eating) and broadly refers to the cellular catabolic processes,in which cytoplasmic...
[期刊论文] 作者:Xing-ding ZHANG,Zheng-hong QIN,Jin WANG,
来源:中国药理学报(英文版) 年份:2010
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[期刊论文] 作者:Jun-Chao WU,Zhong-Qin LIANG,Zheng-Hong QIN,
来源:生物化学与生物物理学报(英文版) 年份:2006
The quality control (QC) system of the endoplasmic reticulum (ER) is an important monitoring mechanism in the protein maturation process, which ensures export o...
,Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative dis
[期刊论文] 作者:Xiao-xia DONG,Yan WANG,Zheng-hong QIN,
来源:中国药理学报(英文版) 年份:2009
A pivotal role for excitotoxicity in neurodegenerative diseases is gaining increasingly more acceptance, but the underlying mechanisms through which it particip...
[期刊论文] 作者:Xiao-qian LIU,Rui SHENG,Zheng-hong QIN,
来源:中国药理学报(英文版) 年份:2009
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,Dual roles of NF-κB in cell survival and implications of NF-κB inhibitors in neuroprotective therap
[期刊论文] 作者:Zheng-hong QIN,Lu-yang TAO,Xin CHEN,
来源:中国药理学报(英文版) 年份:2007
NF-κB is a well-characterized transcription factor with multiple physiological and pathological functions. NF-κB plays important roles in the development and...
[期刊论文] 作者:Fang Lin,Paul F.Reid,Zheng-hong Qin,
来源:中国药理学报(英文版) 年份:2020
Dear Editor,rnA novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), was declared...
[期刊论文] 作者:Ya-Dan WEN,Hui-Ling ZHANG,Zheng-Hong QIN,
来源:神经科学通报(英文版) 年份:2006
Inflammation has been implicated as a secondary mechanism underlying neuronal injury induced by ischemia.A variety of experimental models, including thromboembo...
Neuroprotective effects of pioglitazone is associated with PPARγ-mediated inhibition of NF-κB signal
[会议论文] 作者:Chao WEI,Hui-Ling ZHANG,Zheng-Hong QIN,
来源:中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份:2007
Objective To investigate the neuroprotective actions of pioliotazone (Piog) and the effects of Piog-mediated PPART activation on NF-B signaling pathway in rat model of permanent focal cerebral ischemi...
[期刊论文] 作者:Feng Xu,Jin-Hua Gu,Zheng-Hong Qin,
来源:神经科学通报(英文版) 年份:2012
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[期刊论文] 作者:Ya-ping YANG,Zhong-qin LIANG,Zhen-lun GU,Zheng-hong QIN,
来源:中国药理学报(英文版) 年份:2005
Autophagy is a major cellular pathway for the degradation of long-lived proteins and cytoplasmic organelles in eukaryotic cells. A large number of intracellular...
[期刊论文] 作者:Li ZHANG,Zhen-lun GU,Zheng-hong QIN,Zhong-qin LIANG,
来源:中国药理学报(英文版) 年份:2008
Aim: To determine whether curcumin prevents the adhesion of platelets to brain microvascular endothelial cells (BMECs) cultured in vitro. Methods: [3H]Ad-chine-...
,Crotoxin induces apoptosis and autophagy in human lung carcinoma cells in vitro via activation of t
[期刊论文] 作者:Rong HAN,Hui LIANG,Zheng-hong QIN,Chun-yu LIU,
来源:中国药理学报(英文版) 年份:2014
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[期刊论文] 作者:Wei-Yan ZHANG,Zhen-Lun GU,Zhong-Qin LIANG,Zheng-Hong QIN,
来源:神经科学通报(英文版) 年份:2006
Huntington disease (HD) is a chronic autosomal-dominant neurodegenerative disease. The gene coding Huntingtin has been identified, but the pathogenic mechanisms...
[期刊论文] 作者:Jie Tang,Lei Chen,Zheng-hong Qin,Rui Sheng,
来源:中国药理学报(英文版) 年份:2021
TIGAR (TP53-induced glycolysis and apoptosis regulator) is the downstream target gene of p53,contains a functional sequence similar to 6-phosphofructose kinase/fructose-2,6-bisphosphatase (PFKFB) bisphosphatase domain.TIGAR is mainly locate......
,Caspase-1 inhibitor Ac-YVAD-CHO attenuates quinolinic acid-induced increases in p53 and apoptosis i
[期刊论文] 作者:Yi CAO,Zhen-lun GU,Fang LIN,Rong HAN,Zheng-hong QIN,
来源:中国药理学报(英文版) 年份:2005
Aim: To study the effects of the caspase-1 inhibitor Ac-YVAD-CHO on quinolinic acid (QA)-induced apoptosis. Methods: Rats were pre-treated with intrastriatal in...
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