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[期刊论文] 作者：Zhijian Cao,
来源：中德临床肿瘤学杂志：英文版 年份：2009
这回顾的研究的目的是在乳癌的不同类型上评估 mammographic 成像特征(标记) 并且改进乳癌的早放射学的诊断的目的。方法分析了 118 个病人的 mammographic 图象，乳癌由外科和...
[期刊论文] 作者：Zhijian Cao,
来源：中德临床肿瘤学杂志（英文版） 年份：2004
Objective: The aim of this retrospective study was to evaluate the mammographic imaging features (markers) on different types of breast cancer and improve early...
[会议论文] 作者：Zili Xie,Jing Feng,Weishan Yang,Zhijian Cao,Zongyun Chen,Yingliang Wu,
来源：第12届生物毒素研究及医药应用学术大会 年份：2015
It is well known that the potassium channels (as a kind of shield), are widely blocked or inhibited by the peptide toxins (as a kind of spear) from venomous...
Learning from nature: Peptidomimetic of Hp1404 and identification of K1K8 as an improved anti-infect
[会议论文] 作者：Zhongjie Li,Gaomin Liu,Lanxia Meng,Xiaobo Xu,Wenxin Li,Yingliang Wu,Zhijian Cao,
来源：第12届生物毒素研究及医药应用学术大会 年份：2015
As an alternative class of antimicrobial agent to overcome the drug resistant infections,antimicrobial peptides (AMPs) have gained significant attention.Here, we designed and got an improved antimicro...
The antimicrobial activity of Hp1404,a new antimicrobial peptide from the scorpion Heterometrus pete
[会议论文] 作者：Zhongjie Li,Xiaobo Xu,Lanxia Meng,Qian Zhang,Luyang Cao,Wenxin Li,Yingliang Wu,Zhijian Cao,
来源：10th IST Asia Pacific Congress on Animal , Plant and Microbi 年份：2014
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Molecular basis for toxin resistance of Mesobuthus martensii voltage-gated potassium channel: insigh
[会议论文] 作者：Zili Xie,Yange Lang,Jing Chen,Chuangeng Zhang,Xinxin Li,Yingliang Wu,Zhijian Cao,Wenxin Li,
来源：第12届生物毒素研究及医药应用学术大会 年份：2015
It remains unclear why scorpions are immune to own venoms containing various neurotoxins specific for the mammalian or insect ion channels.The functional ch...
The antimicrobial activity of Hp1404,a new antimicrobial peptide from the scorpion Heterometrus pete
[会议论文] 作者：Zhongjie Li,Xiaobo Xu,Lanxia Meng,Qian Zhang,Luyang Cao,Wenxin Li,Yingliang Wu,Zhijian Cao,
来源：10th IST Asia Pacific Congress on Animal , Plant and Microbi 年份：2014
Antimicrobial peptides have attracted much interest as a novel class of antibiotics against a variety of microbes including antibiotics resistant strains.In this study,a new cationic antimicrobial pep...
Molecular basis for toxin resistance of Mesobuthus martensii voltage-gated potassium channel: insigh
[会议论文] 作者：Chuangeng Zhang,Zili Xie,Xinxin Li,Jing Chen,Yange Lang,Wenxin Li,Zhijian Cao,Yingliang Wu,
来源：第12届生物毒素研究及医药应用学术大会 年份：2015
It remains unclear why scorpions are immune to own venoms containing various neurotoxins specific for the mammalian or insect ion channels.The functional characterization of scorpion ion channels can...
[会议论文] 作者：Song,Zheng Fan,Zhenhuan Zhao,Wei Hong,Zhengyang Zeng,Nicolai E.Savaskan,Wenxin Li,Yingliang Wu,Zhijian Cao,
来源：第12届生物毒素研究及医药应用学术大会 年份：2015
A new peptide precursor, termed Sj7170, was characterized from the venomous gland cDNA library of the scorpion Scorpiopsjendeki.Sj7170 was deduced to be a 62 amino acid peptide cross-linked by five di...
[会议论文] 作者：Lanxia Meng,Zili Xie,Qian Zhang,Yang Li,Fan Yang,Zongyun Chen,Wenxin Li,Zhijian Cao,Yingliang Wu,
来源：第12届生物毒素研究及医药应用学术大会 年份：2015
The structural similarity between the defensins and scorpion neurotoxins suggests might evolve from a common ancestor.However, there is no direct experimental evidence demonstrating functional linkage...
[会议论文] 作者：Jing Feng,Zili Xie,Weishan Yang,Fang Xiang,Yonghui Zhao,Zhijian Cao,Wenxin Li,Zongyun Chen,Yingliang,
来源：第12届生物毒素研究及医药应用学术大会 年份：2015
The human β-defensin 2 (hBD2), as a Kv1.3 channel inhibitor with the unique molecular mechanism and novel immune modulatory function, suggests that human β-defensins are a kind of novel channel ligand...
Design of histidine-rich peptides with enhanced bioavailability and inhibitory activity against hepa
[会议论文] 作者：Wei Hong,Runhong Zhang,Zhiyong Di,Yawen He,Zhenhuan Zhao,Jun Hu,Yingliang Wu,Wenxin Li,Zhijian Cao,
来源：第十一届中国生物毒素研究及医药应用年会 年份：2013
Recently,peptide drugs have evolved into mainstream therapeutics,representing a significant portion of the pharmaceutical market.However,their bioavailability remains to be improved compared with that...
A Tat-conjugated peptide nucleic acidinhibits Hepatitis B virusreplicationin vitro and in vivo by ta
[会议论文] 作者：Zhengyang Zeng,Yingliang Wu,Fangfang Li,Yongxiang Liu,Wei Hong,Wenxin Li,Yange Lang,Zhijian Cao,Xianzheng,
来源：第12届生物毒素研究及医药应用学术大会 年份：2015
Hepatitis B virus (HBV) infection significantly increases the risk for the development of chronic active hepatitis, cirrhosis, and primary hepatocellular ca...
A Tat-conjugated peptide nucleic acidinhibits Hepatitis B virusreplicationin vitro and in vivo by ta
[会议论文] 作者：,Wei Hong,Yange Lang,Fangfang Li,Yongxiang Liu,Zeyong Li,Yingliang Wu,Wenxin Li,Xianzheng Zhang,Zhijian Cao,
来源：第12届生物毒素研究及医药应用学术大会 年份：2015
Hepatitis B virus (HBV) infection significantly increases the risk for the development of chronic active hepatitis, cirrhosis, and primary hepatocellular carcinoma, which is still a major public healt...
[期刊论文] 作者：Zhiqiang Xia,Xingchen Guo,Minjun Gao,Fang Sun,Yuting Cheng,Yingliang Wu,Wenxin Li,Syed Abid Ali,Zhijian Cao,
来源：中国病毒学 年份：2018
Dengue virus (DENV) and Zika virus (ZIKV) have spread throughout many countries in the developing world and infect millions of people every year,causing severe harm to human health and the economy.Unfortunately,there are few effective vacci......
[会议论文] 作者：Xiaobo Xu,Zhiyong Di,Yawen He,Zhongjie Li,Zhijian Cao,Yingliang Wu,Wenxin Li,Zhigui Duan,Jianglin Li,,
来源：10th IST Asia Pacific Congress on Animal , Plant and Microbi 年份：2014
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[会议论文] 作者：Xiaobo Xu,Zhigui Duan,Zhiyong Di,Yawen He,Jianglin Li,Zhongjie Li,Chunliang Xie,Xiongzhi Zeng,Zhijian Cao,
来源：10th IST Asia Pacific Congress on Animal , Plant and Microbi 年份：2014
Mesobuthus martensii is a widely distributed scorpion species in China.Its venom contains various compounds with different biological activities,which can be of potential medicinal value.In this study...
[会议论文] 作者：,Wenxin Li,Yingliang Wu,Youtian Hu,Hong Yi,Shijin Yin,Song Han,Jun Hu,Zongyun Chen,Weishan Yang,Zhijian Cao,
来源：第十一届中国生物毒素研究及医药应用年会 年份：2013
Potassium channel functions are often deciphered by using selective and potent scorpion toxins.Among these toxins,only a limited subset is capable to selectively block small conductance Ca2+-activated...
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