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CRISPR/Cas9-mediated gene knockout reveals a guardian role of NF-κB/RelA in maintaining the homeosta
[期刊论文] 作者：Ping Wang,Zunpeng Liu,Xiaoqian,
来源：蛋白质与细胞：英文版 年份：2018
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[期刊论文] 作者：Shijia Bi,Zunpeng Liu,Zeming Wu,Zehua Wang,Xiaoqian Liu,Si Wang,Jie Ren,Yan Yao,Weiqi Zhang,Moshi Song,
来源：蛋白质与细胞 年份：2020
SIRT7,a sirtuin family member implicated in aging and disease,is a regulator of metabolism and stress responses.It remains elusive how human somatic stem cell p...
,CRISPR/Cas9-mediated gene knockout reveals a guardian role of NF-κB/RelA in maintaining the homeost
[期刊论文] 作者：Ping Wang,Zunpeng Liu,Xiaoqian Zhang,Jingyi Li,Liang Sun,Zhenyu Ju,Jian Li,Piu Chan,Guang-Hui Liu,Weiqi,
来源：蛋白质与细胞 年份：2018
Vascular cell functionality is critical to blood vessel homeostasis.Constitutive NF-κB activation in vascular cells results in chronic vascular inflammation,le...
[期刊论文] 作者：Lingling Geng,Zunpeng Liu,Si Wang,Shuhui Sun,Shuai Ma,Xiaoqian Liu,Piu Chan,Liang Sun,Moshi Song,Weiqi,
来源：蛋白质与细胞 年份：2019
Dear Editor,Aging is the leading risk factor for many chronic diseases,accounting for almost 60％ of all deaths worldwide.How to achieve healthy aging,alleviate a...
[期刊论文] 作者：Hongyu Li,Zeming WU,Xiaoqian Liu,Sheng Zhang,Qianzhao Ji,Xiaoyu Jiang,Zunpeng Liu,Si Wang,Jing Qu,Weiqi,
来源：蛋白质与细胞 年份：2020
Dear Editor,rnAs the most prevalent DNA methylation modification in prokaryotes, DNA N6-methyladenosine (6mA)in eukaryotic genomes has recently been observed in...
[期刊论文] 作者：Fang Cheng,Si Wang,Moshi Song,Zunpeng Liu,Ping Liu,Lei Wang,Yanjiang Wang,Qian Zhao,Kaowen Yan,Piu Chan,
来源：蛋白质与细胞 年份：2019
Dear Editor,Safeguarding cellular redox homeostasis is crucial for maintaining organism health and preventing diseases.Oxidative stress,often characterized by d...
[期刊论文] 作者：Lingling Geng,Zunpeng Liu,Weiqi Zhang,Wei Li,Zeming Wu,Wei Wang,Ruotong Ren,Yao Su,Peichang Wang,Liang,
来源：蛋白质与细胞 年份：2019
Aging increases the risk of various diseases.The main goal of aging research is to find therapies that attenuate aging and alleviate aging-related diseases.In t...
[期刊论文] 作者：Chen Ling,Zunpeng Liu,Moshi Song,Weiqi Zhang,Si Wang,Xiaoqian Liu,Shuai Ma,Shuhui Sun,Lina Fu,Qun Chu,
来源：蛋白质与细胞 年份：2019
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencaphalopathy (CADASIL) is a rare hereditary cerabrovascular disease caused by a NO...
[期刊论文] 作者：Jingyi Li,Yuxuan Zheng,Pengze Yan,Moshi Song,Si Wang,Liang Sun,Zunpeng Liu,Shuai Ma,Juan Carlos Izpisua,
来源：国家科学评论（英文版） 年份：2021
Aging-related degeneration of pancreatic islet cells contributes to impaired glucose tolerance and diabetes.Endocrine cells age heterogeneously,complicating the...
FOXO3-engineered human mesenchymal progenitor cells efficiently promote cardiac repair after myocard
[期刊论文] 作者：Jinghui Lei,Si Wang,Wang Kang,Qun Chu,Zunpeng Liu,Liang Sun,Yun Ji,Concepcion Rodriguez Esteban,Yan Yao,
来源：蛋白质与细胞 年份：2021
Dear Editor,rnMyocardial infarction(MI)is the irreversible cardiomyocyte death resulting from prolonged oxygen deprivation due to obstructed blood supply(ischem...
,Rescue of premature aging defects in Cockayne syndrome stem cells by CRISPR/ Cas9-mediated gene cor
[期刊论文] 作者：Si Wang,Zheying Min,Qianzhao Ji,Lingling Geng,Yao Su,Zunpeng Liu,Huifang Hu,Lixia Wang,Weiqi Zhang,Keiichiro,
来源：蛋白质与细胞 年份：2020
Cockayne syndrome (CS) is a rare autosomal recessire inherited disorder characterized by a variety of clinical features,including increased sensitivity to sunli...
,Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasis
[期刊论文] 作者：Xing Zhang,Zunpeng Liu,Xiaoqian Liu,Si Wang,Yiyuan Zhang,Xiaojuan He,Shuhui Sun,Shuai Ma,Ng Shyh-Chang,
来源：蛋白质与细胞 年份：2019
RAP1 is a well-known telomere-binding protein,but its functions in human stem cells have remained unclear.Here we generated RAP1-deficient human embryonic stem...
Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration
[期刊论文] 作者：Chuqian Liang,Zunpeng Liu,Moshi Song,Wei Li,Zeming Wu,Zehua Wang,Qiaoran Wang,Si Wang,Kaowen Yan,Liang,
来源：细胞研究（英文版） 年份：2021
Accumulating evidence indicates an association between the circadian clock and the aging process.However,it remains elusive whether the deregulation of circadia...
[期刊论文] 作者：Liu,Wenqing Le,Lihui Xie,He Li,Wen Wen,Si Wang,Shuai Ma,Zhaohao Huang,Jinguo Ye,Wen Shi,Yanxia Ye,Zunpeng Liu,
来源：蛋白质与细胞 年份：2020
Age-associated changes in immune cells have been linked to an increased risk for infection.However,a global and detailed characterization of the changes that hu...
[期刊论文] 作者：Fang Wang,Weiqi Zhang,Qiaoyan Yang,Yu Kang,Yanling Fan,Jingkuan Wei,Zunpeng Liu,Shaoxing Dai,Hao Li,Zifan,
来源：蛋白质与细胞 年份：2020
Many human genetic diseases,including Hutchinson-Gilford progeria syndrome(HGPS),are caused by single point mutations.HGPS is a rare disorder that causes premat...
[期刊论文] 作者：Shuai Ma,Shuhui Sun,Jiaming Li,Yanling Fan,Jing Qu,Liang Sun,Si Wang,Yiyuan Zhang,Shanshan Yang,Zunpeng Liu,
来源：细胞研究（英文版） 年份：2021
Aging is a major risk factor for many diseases,especially in highly prevalent cardiopulmonary comorbidities and infectious diseases including Coronavirus Diseas...
[期刊论文] 作者：Li,Xiaojuan He,Ruotong Ren,Weiqi Zhang,Moshi Song,Huifang Hu,Feifei Liu,Guoqiang Sun,Shuhui Sun,Zunpeng Liu,
来源：蛋白质与细胞 年份：2021
Dear Editor,rnThe retina is a light-sensitive highly-organized tissue,which is vulnerable to aging and age-related retinal diseases.Specifically,progressive retinal degeneration leads to visual function deterioration and vision impairment i......
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