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[会议论文] 作者：Qian Mei,Xiang Li,Jing Nie,Xiaohui Wang,Weidong Han,Mingzhou Guo,
来源：第四届国际肿瘤表观遗传学大会 年份：2014
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[期刊论文] 作者：Zhitao Gao,Chuan Tong,Yao Wang,Deyun Chen,Zhiqiang Wu,Weidong Han,
来源：遗传学报 年份：2019
Chimeric antigen receptor T-cell (CAR T) therapy is a kind of effective cancer immunotherapy.However,designing CARs remains a challenge because many targetable...
[期刊论文] 作者：Xiaohui Wang,Zhiqiang Wu,Wei Qiu,Ping Chen,Xiang Xu,Weidong Han,
来源：医学前沿 年份：2020
Chimeric antigen receptor (CAR) T cells have been indicated effective in treating B cell acute lymphoblastic leukemia and non-Hodgkin lymphoma and have shown en...
[会议论文] 作者：Qian Mei,Xiang Li,Jing Nie,Xiaohui Wang,Mingzhou Guo,Weidong Han,
来源：第四届国际肿瘤表观遗传学大会 年份：2014
Solid tumor patients when progressed into advanced stages have poor prognosis even treated with intensive salvage regimens and are welcome subjects for clinical trial of new agents.Aberrant DNA methyl...
[期刊论文] 作者：Dongdong Ti,Xin Yan,Jianshu Wei,Zhiqiang Wu,Yao Wang,Weidong Han,
来源：中国癌症研究（英文版） 年份：2022
Immunotherapy has revolutionized cancer treatment and substantially improved patient outcomes with respect to multiple types of tumors.However,most patients cannot benefit from such therapies,mainly due to the intrinsic low immunogenicity o......
[期刊论文] 作者：rg Teichmann,Shibani Bose,Weidong Han,Xiaoming Wang,
来源：城市道桥与防洪 年份：2018
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生、测量监控等方面人手,介绍了S226海滨大桥...
Chimeric antigen receptor-modified T cells for the immunotherapy of patients with EGFR-expressing ad
[期刊论文] 作者：Kaichao Feng,Yelei Guo,Hanren Dai,Yao Wang,Xiang Li,Hejin Jia,Weidong Han,,
来源：Science China(Life Sciences) 年份：2016
The successes achieved by chimeric antigen receptor-modified T(CAR-T) cells in hematological malignancies raised the possibility of their use in non-small lung...
[期刊论文] 作者：Xiaolei Li,Hanren Dai,Xian Li,Ping Li,Wenbin Qian,Aibin Liang,Weidong Han,
来源：中国免疫学杂志（英文版） 年份：2022
Chimeric antigen receptor (CAR) T-cell therapy utilizes patients\' own T lymphocytes that are engineered to attack cancer cells[1-3].With the US Food and Drug Administration (FDA) approval of four CD19-and one BCMA-targeted CAR therapy for ......
Chimeric antigen receptor (CAR)-modified natural killer cell-based immunotherapy and immunological s
[期刊论文] 作者：Dongfang Liu,Shuo Tian,Kai Zhang,Wei Xiong,Ndongala Michel Lubaki,Zhiying Chen,Weidong Han,
来源：蛋白质与细胞 年份：2017
Cytotoxic T lymphocytes (CTLs) and natural killer (NK)cells contribute to the body’s immune defenses.Current chimeric antigen receptor (CAR)-modified T cell im...
[期刊论文] 作者：Dongdong Ti,Miaomiao Bai,Xiaolei Li,Jianshu Wei,Deyun Chen,Zhiqiang Wu,Yao Wang,Weidong Han,
来源：中国科学：生命科学（英文版） 年份：2021
Impaired tumor-specific effector T cells contribute to tumor progression and unfavorable clinical outcomes.As a compensatory T cell-dependent cancer immunoediti...
,Phase Ⅰ study of chimeric antigen receptor modified T cells in treating HER2-positive advanced bili
[期刊论文] 作者：Kaichao Feng,Yang Liu,Yelei Guo,Jingdan Qiu,Zhiqiang Wu,Hanren Dai,Qingming Yang,Yao Wang,Weidong Han,
来源：蛋白质与细胞 年份：2018
This phase Ⅰ clinical trial (NCT01935843) is to evaluate the safety,feasibility,and activity of chimeric antigen receptor-engineered T cell (CART) immunotherap...
CD138-directed adoptive immunotherapy of chimeric antigen receptor (CAR)-modified T cells for multip
[会议论文] 作者：Guo,Meixia Chen,Qingwang Hart,Fan Hui,Hanren Dai,Wenying Zhang,Yajing Zhang,Yao Wang,Hongli Zhu,Weidong Han,
来源：第十四届全国肿瘤生物治疗大会 年份：2015
Adoptive immunotherapy with T cells expressing a tumor-associated chimeric antigen receptor (CAR) provides a promising approach for tumor therapy.We designe...
,Effective and persistent antitumor activity of HER2-directed CAR-T cells against gastric cancer cel
[期刊论文] 作者：Yanjing Song,Chuan Tong,Yao Wang,Yunhe Gao,Hanren Dai,Yelei Guo,Xudong Zhao,Yi Wang,Zizheng Wang,Weidong Han,
来源：蛋白质与细胞 年份：2018
Human epidermal growth factor receptor 2 (HER2) proteins are overexpressed in a high proportion of gastric cancer (GC) cases and affect the maintenance of cance...
Human umbilical cord-derived mesenchymal stem cells elicit macrophages into an anti-inflammatory phe
[会议论文] 作者：Zongyan Xie,Nan Zhang,Chuan Tong,Haojie Hao,Jiejie Liu,Weidong Han,Li Zang,Kun Zhao,Yiming Mu,Yu Cheng,
来源：首届全国组织修复与再生医学大会暨国际组织修复与再生医学学术研讨会 年份：2015
...
Human umbilical cord-derived mesenchymal stem cells elicit macrophages into an anti-inflammatory phe
[会议论文] 作者：Zongyan Xie,Nan Zhang,Yiling Si,Jiejie Liu,Weidong Han,Chuan Tong,Haojie Hao,Yu Cheng,Kun Zhao,Yiming,
来源：中华医学会第十四次全国内分泌学学术会议 年份：2015
...
Human umbilical cord-derived mesenchymal stem cells elicit macrophages into an anti-inflammatory phe
[会议论文] 作者：Xie,Haojie Hao,Chuan Tong,Yu Cheng,Jiejie Liu,Yaping Pang,Nan Zhang,Kun Zhao,Li Zang,Yiming Mu,Weidong Han,
来源：首届全国组织修复与再生医学大会暨国际组织修复与再生医学学术研讨会 年份：2015
Objective: Type 2 diabetes mellitus (T2D), one of the most widespread endocrine disorders, is characterized with insulin resistance and relatively insulin deficiency.Insulin resistance, typically pres...
Human umbilical cord-derived mesenchymal stem cells elicit macrophages into an anti-inflammatory phe
[会议论文] 作者：Zongyan Xie,Haojie Hao,Chuan Tong,Yu Cheng,Jiejie Liu,Yiling Si,Nan Zhang,Kun Zhao,Li Zang,Yiming Mu,Weidong Han,
来源：中华医学会第十四次全国内分泌学学术会议 年份：2015
Objective Type 2 diabetes mellitus (T2D), one of the most widespread endocrine disorders, is characterized by insulin resistance and relative insulin deficiency.Insuin resistance,typically present fro...
Effective and persistent antitumor activity of HER2-directed chimeric antigen receptor-modified T ce
[会议论文] 作者：Yanjing Song,Yao Wang,Chuan Tong,Yunhe Gao,Hanren Dai,Yelei Guo,Hongqing Xi,Xudong Zhao,Yi Wang,Weidong Han,
来源：第十二届国际胃癌学术会议 年份：2017
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Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of cli
[期刊论文] 作者：Zhang,Xiaoming Wei,Yukun Guan,Jiejie Liu,Kaichao Feng,Miao Jing,Xurui Wang,Yun-Cai Liu,Qian Mei,Weidong Han,
来源：细胞研究（英文版） 年份：2020
CD8+ T cell-mediated cancer clearance is often suppressed by the interaction between inhibitory molecules like PD-1 and PD-L1,an interaction acts like brakes to...
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