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BCKDK promotes colorectal cancer tumorigenesis via directly activating MEK1 at Ser221,and phenylbuty
[会议论文] 作者：PeiPei Xue,QiuHong Duan,HuiMing Sun,JuanJuan Xiao,Olesia S.Vishchuk,XiaoYu Zeng,JianMin Zhang,Zhe Wang,
来源：中国生物化学与分子生物学会2016年全国学术会议 年份：2016
Background & Aims: Colorectal cancer(CRC)is the third most commonly diagnosed cancer in males and the second in females.The branched-chain a-keto acid dehydrogenase kinase(BCKDK)is a rate-limiting enz...
[期刊论文] 作者：WANG Nan,CHEN Yongnan,LIU Shuangshuang,ZHU Lixia,ZHU Shidong,ZHAO Yongqing,ZHANG Long,HAO Jianmin,ZHANG,
来源：武汉理工大学学报（材料科学版）（英文版） 年份：2020
To improve the low thermal conductivities and poor wear resistances of TC4 (Ti-6Al-4V) alloy, the most widely used titanium alloy, the surface of TC4 alloys is modified by electroplating deposition of Ni and Cu layers, and then heat-treated......
Establishment of a novel triple-transgenic mouse: conditionally and liver-specifically expressing he
[会议论文] 作者：,Zhikai Xu,Xin Lü,Haiyun Lan,Ya Zhao,Jing Yang,Mengning Sun,Yingfeng Lei,Min Yao,Xiaojun Huang,Jianmin Zhang,
来源：中华医学会疫苗可预防疾病及新发传染病2013年郑州论坛 年份：2013
Background It is well known that NS3/4A protease plays crucial roles in the hepatitis C virus(HCV) replication.NS3/4A protease also results to virus-mediated immune evasion and persistence of infectio...
Association of Plasminogen activator inhibitor-1gene polymorphism4G/4G genotype and post-operative d
[会议论文] 作者：jianmin zhang,Aixian Tian,Jianxiong Ma,Tao Wan,Xiaolei Sun,Ying Wang,Lei Sun,Jianbao Wang,Bin Lu,Hongqiang,
来源：中华医学会第十七届骨科学术会议暨第十届COA国际学术大会 年份：2015
Objective: To explore the possible relationship between PAI-l gene 4G/5G polymorphism and PAI-1 plasma level and deep venous thrombosis in patients after major orthopedic surgeries....
The relationship between OX40-OX40L and NFAT signaling pathway in the pathogenesis process of Kawasa
[会议论文] 作者：Yuwen Lv,Haitao Lv,Ling Sun,Jie Huang,Weiguo Qian,wanping Zhou,Qiuqin Xu,Yueyue Ding,Jianmin Zhang,Lei,
来源：中华医学会第二十次全国儿科学术大会 年份：2015
Background: Previous studies and our research have shown that NFAT signal pathway participated in the pathogenesis of Kawasaki disease(KD)....
[会议论文] 作者：Yangshun Tang,Bo Feng,Bin Chen,Yunjian Dai,Yi Wang,Dengchang Wu,Cenglin Xu,Shuang Wang,Junmin Zhu,Jianmin Zhang,
来源：The 6th FAONS Congress and 11th Biennial Conference of CNS(第 年份：2015
Objective Febrile seizures(FS)are the most common seizure types in infants,and approximately 3-6%of them develop into temporal lobe epilepsy in adult....
[会议论文] 作者：ZHAO Zhigang,JIANG Ling,GUO Xiuping,GAI Ying,WU Chuanyin,ZHAI Huqu,WANG Haiyang,WAN Jianmin,ZHANG Yunhui,
来源：2013全国植物生物学大会 年份：2013
Indole-3-acetic acid (IAA), the natural auxin in plants, regulates many aspects of plant growth and development.Extensive analyses have elucidated the compo...
[会议论文] 作者：Zheyong Liang,Fang He,Lu Yang,Pingping Li,Yina Jiang,Bo Wang,Can Zhou,Yaochun Wang,Yu Ren,Jin Yang,Jianmin Zhang,
来源：第五届广州国际肿瘤学会议暨第一届中国抗癌协会肿瘤靶向治疗专业委员会年会 年份：2016
Purpose: Loss or dysfunction of tumor suppressor RB is a common feature of various tumors,and it contributes to cancer cell stemness and drug resistance.How...
[会议论文] 作者：Juanjuan Xiao,Ruijuan Xiu,Qin Tian,Huaxiong Pan,Ling Zou,Fei Wang,Tengfei Ma,Ping Yuan,Lin Liu,Jianmin Zhang,
来源：中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 年份：2018
TMZ(temozolomide)treatment,as first-line chemotherapy in GBM(glioblastma),faced with drug resistance.Recent studies emphasize that TMZ resistance is associated with autophagy,but the mechanism remaine...
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