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[会议论文] 作者：Youzhi Miao,Dongyang Liu,Ruifu Zhang,
来源：第十六次全国环境微生物学学术研讨会 年份：2013
Many microorganisms, especially filamentous fungi, could efficiently degrade lignocellulose, which is a complex carbohydrate and aromatic polymers in plant cell wall and is the most abundant natural m...
Prediction of First-in-Human Dose of CPRC1 Using Allometric Scaling, IVIVE and PK/PD Modeling Method
[会议论文] 作者：Yang Liu,Dongyang Liu,Ji Jiang,Pei Hu,
来源：第四届定量药理学与新药评价国际会议·2013(The 4th International Symposium in Qu 年份：2013
Diabetes mellitus is one of the most common chronic disease in the world, CPRC 1 is a novel dipeptidylpeptidase-Ⅳ(DPP-4) inhibitor which was proposed to control hyperglycemia in patients with type 2 d...
[会议论文] 作者：Jia Chen,Dongyang Liu,Qian Zhao,Ji Jiang,Pei Hu,
来源：第四届定量药理学与新药评价国际会议·2013(The 4th International Symposium in Qu 年份：2013
Objective:Icotinib is a potent small-molecule inhibitor of epidermal growth factor receptor (EGFR)-tyrosine kinase (TKI), which was designed for the treatment of non-small cell lung cancer (NSCLC).It...
A Mechanistic Pharmacokinetic-Pharmacodynamic Model for the Effect of Esomeprazole in Healthy Subjec
[会议论文] 作者：Dongyang Liu,Hong Yang,Jiaming Qian,Ji Jiang,Pei Hu,
来源：第四届定量药理学与新药评价国际会议·2013(The 4th International Symposium in Qu 年份：2013
Esomeprazole has proved to be effective for the treatment of gastroesophogeal reflux disease (GERD) and ulcers, where intra-gastric pH value is a biomarker to indicate esomeprazole effects on these di...
[会议论文] 作者：Rui Chen,Dongyang Liu,Jun Shi,Ji Jiang,Pei Hu,
来源：第四届定量药理学与新药评价国际会议·2013(The 4th International Symposium in Qu 年份：2013
Objective:In vitro information on dextromethorphan (DXM) and the Advanced Dissolution Absorption Metabolism (ADAM) model, incorporated into PBPK simulator Simcyp(@) (v.12) were used to investigate dif...
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