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Probing Druggability on Interface and its Allosteric Regulation Mechanism on Drug Screening for CXCR
[会议论文] 作者：Liting Shen,Jianfang Chen,Xingyu Du,Yanzhi Guo,Menglong Li,Xuemei Pu,
来源：2019中国化学会第十五届全国计算(机)化学学术会议 年份：2019
Modulating protein-protein interactions(PPIs)with small drug-like molecules targeting it exhibits great promising in modern drug discovery....
Exploring Activation Mechanism Induced by Glutamate for one Homodimer of Class C GPCRs via Molecular
[会议论文] 作者：Ting Lei,Fuhui Zhang,Nian Xu,Zhenxin Hu,Menglong Li,Xuemei Pu,
来源：2019中国化学会第十五届全国计算(机)化学学术会议 年份：2019
Metabotropic glutamate receptors of class C GPCRs exist as constitutive dimers,which play important roles in activating excitatory synapses of the central nerve system.However,due to lack of crystal s...
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