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Discovery of New SIRT2 Inhibitors by Utilizing a Consensus Docking/Scoring Strategy and Structure-Ac
[会议论文] 作者:ShenzhenHuang[1]ChunliSong[2]XiangWang[3]GuoZhang[2]YanlinWang[1]XiaojuanJiang[1]QizhengSun[1]LuyiHuang[1]RongXiang[3]YiguoHu[1]LinliLi[2]ShengyongYang[1],
来源:第九届国际分子模拟与信息技术应用学术会议(ICMS&I2018) 年份:2018
SIRT2,which is a NAD+(nicotinamide adenine dinucleotide)dependent deacetylase,has been demonstrated to play an important role in the occurrence and developm...
[期刊论文] 作者:张俊1, 2, 3, 李天匀1, 2, 3, 朱翔1, 2, 3,
来源:中国舰船研究 年份:2018
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[期刊论文] 作者:邢璐璐1, 2, 3 祖尧1, 2, 3 李伟明1, 2, 3,
来源:基因组学与应用生物学 年份:2018
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[期刊论文] 作者:鲁凯1, 2, 3 高建忠1, 2, 3* 温彬1, 2, 3,
来源:基因组学与应用生物学 年份:2018
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Discovery of Selective Protein Arginine Methyltransferase 5 (PRMT5) Inhibitors and Biological Evalua
[会议论文] 作者:SenJi[1]ShuangMa[1]Wen-JingWang[1]Shen-ZhenHuang[1]Tian-qiWang[2]RongXiang[2]Yi-GuoHu[1]QiangChen[1]Lin-LiLi[3]Sheng-YongYang[1],
来源:第九届国际分子模拟与信息技术应用学术会议(ICMS&I2018) 年份:2018
PRMT5 is an important protein arginine methyltransferase that catalyzes the symmetric dimethylation of arginine resides on histones or non-histone substrate...
[会议论文] 作者:BingZhao[1]YanlingZhang[1]YinongHuang[1]JinchaoYu[1]YaranLi[1]QiWang[2]YixinMa[2]Hou-YanSong[3]MinYu[1]WeiMo[1],
来源:第九届国际分子模拟与信息技术应用学术会议(ICMS&I2018) 年份:2018
Currently,anticoagulants would be used to prevent thrombosis.Thrombin is an effector enzyme for haemostasis and thrombosis.We designed a direct thrombin inh...
[会议论文] 作者:YulongGe[1]XuhaiYang[2]WeijinQin[1]HangSu[1]MeifangWu[1]YuanxiWang[1]ShengliWang[3],
来源:第九届中国卫星导航学术年会 年份:2018
International time transfer experiment based on GPS-and BDS-precise point positioning(PPP)technique is carried out using final(ISC)and rapid(ISR)precise sat...
[会议论文] 作者:JiaZhu[1]JiaqiLun[1]XumingWang[1]MinYang[2]ChangqinHuang[1]GabrielPuiCheongFung[3],
来源:第22届全球华人计算机教育应用大会 年份:2018
Traditional automated essay scoring methods heavily rely on feature engineering to evaluate and assign scores to essays,which means the quality of the selec...
Highly Uniform Nanocomplex with a Dissociable Thiolated Coating to Improve Oral Protein Drug Deliver
[会议论文] 作者:HoukuanTian[1]LixinLiu[1]KamWLeong[2]Hai-QuanMao[3]ZhijiaLiu[1]YongmingChen[1],
来源:第三届国际纳米药物大会 ChinaNanomedicine 2018 The 3rd International Con 年份:2018
Protein drugs are widely explored to prevent or treat chronic or inflammatory diseases and cancers because of their significant advantages in high specifici...
[会议论文] 作者:ZongxiLI[1]DiZOU[1]HaoranXIE[1]FuLeeWANG[2]MaigaCHANG[3],
来源:第22届全球华人计算机教育应用大会 年份:2018
With such advantages as being fun,effective and interactive,game-based learning has become a new trend in education field.In the course Web Intelligence(INT...
[会议论文] 作者:Hai-fengSun[1]Jian-yuSu[1]LiangZhao[2]Zhi-weiLiu[3]Hai-yanFang[1],
来源:第九届中国卫星导航学术年会 年份:2018
This paper addresses the problem of building the X-ray pulsar timing model that is an essential work for X-ray pulsar navigation(XNAV).We propose a theoreti...
[会议论文] 作者:WanshengZou[1]ZhiWang[2]QishengSong[3]PinhongYang[1]WenbinWang[1],
来源:第四届全国流域生态保护与水污染控制研讨会 年份:2018
The recruitment of dormant Microcystis cells to the water from the sediments surface under eutrophic conditions is influenced by many environmental factors,...
[会议论文] 作者:WanqingLiu[1]JuqingZhang[1]GuanwenHuang[1]GeWang[2]ZhenZhang[3],
来源:第九届中国卫星导航学术年会 年份:2018
Signal strength of indoor location is easily influenced by environment,multipath refraction and human disturbance.Considering the characters that long dista...
Rapid Ambiguity Resolution Algorithm for Multi-constellation between Reference Stations Based on Amb
[会议论文] 作者:RuichengZhang[1]ChengfaGao[1]ShuguoPan[2]ZhiyueYan[3]QingZhao[1],
来源:第九届中国卫星导航学术年会 年份:2018
The development of multi-GNSS remarkably increased the number of available satellites,but how to solve the multi-dimensional ambiguity parameters quickly an...
[会议论文] 作者:YuChen[1]HaiyongLuo[2]FangZhao[1]WenhuaShao[1]QuWang[3],
来源:第九届中国卫星导航学术年会 年份:2018
Turn detection can be widely used in location navigation,user behavior identification,and scene awareness.Accurate real-time identification of pedestrian tu...
[会议论文] 作者:WeiJin[1]YingLiu[2]ZhihengZhang[1]XiaoxiJin[1]QiongLiu[3]XiaochenJin[3],
来源:第九届中国卫星导航学术年会 年份:2018
X-Ray pulsar navigation is a new technology for astronavigation.It's an effective supplement to the satellite navigation which is widely used at present.It...
Synthetization of fingerprint recognition and trilateration for Wi-Fi indoor Localization through li
[会议论文] 作者:JunxiTian[1]ZeboZhou[2]JinWu[1]ShuangDu[1]ChangganXiang[3]ChanghongKuang[3],
来源:第九届中国卫星导航学术年会 年份:2018
In traditional indoor localization,fingerprint localization algorithm fully considers the influences of multipath signals and static obstacles but degrades...
[会议论文] 作者:Qi-SongTong[1]YangChen[2]HuaHuang[1]WeiXu[1]Jin-ZhiDu[3]JunWang[3],
来源:第三届国际纳米药物大会 ChinaNanomedicine 2018 The 3rd International Con 年份:2018
Cancer therapy by employing synthetic materials as delivery carriers has made great progress in recent decades.However,the therapeutic efficacy of nanocarri...
In vitro selection of aptamers and the development of a highly specific and sensitive chemiluminesce
[会议论文] 作者:LingYang[1]HengjiaNi[2]ChenglongLi[1]XiyaZhang[1]KaiWen[1]YuebinKe[3]HuijuanYang[1]WeiminShi[1]SuxiaZhang[1]JianzhongShen[1]ZhanhuiWang[1],
来源:第九届国际分子模拟与信息技术应用学术会议(ICMS&I2018) 年份:2018
Antibody-based sensors are the most widely used for screening antibiotic residues in food samples.However,these sensors always suffer from cross-reacting an...
From Lead to Drug Candidate:Optimization of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine De
[会议论文] 作者:Chun-HuiZhang[1]KaiChen[1]YanJiao[1]Lin-LiLi[2]Ya-PingLi[1]Rong-JieZhang[1]Ming-WuZheng[1]LeiZhong[1]Shen-ZhenHuang[1]Chun-LiSong[2]Wan-TingLin[1]JiaoYang[1]RongXiang[3]BingPeng[1]Jun-HongHan[1]Guang-,
来源:第九届国际分子模拟与信息技术应用学术会议(ICMS&I2018) 年份:2018
Herein we report the sophisticated process of structural optimization toward a previously disclosed Src inhibitor,compound 1,which showed high potency in th...
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