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Focused evaluation of the roles of macrophages in chimeric antigen receptor (CAR) T cell therapy ass
[期刊论文] 作者：Hanfei Guo,Lei Qian,Jiuwei Cui,
来源：癌症生物学与医学（英文版） 年份：2022
Cytokine release syndrome (CRS) is a major obstacle to the widespread clinical application of chimeric antigen receptor (CAR) T cell therapies. CRS can also be induced by infections (such as SARS-CoV-2), drugs (such as therapeutic antibodie......
[期刊论文] 作者：Lin Qian,Fan Zhang,Miao Yin,Qunying Lei,
来源：癌症生物学与医学（英文版） 年份：2022
Metabolic remodeling is a key feature of cancer development. Knowledge of cancer metabolism has greatly expanded since the first observation of abnormal metabolism in cancer cells, the so-called Warburg effect. Malignant cells tend to modif......
[期刊论文] 作者：Dong-Jie Qian,
来源：中国物理B（英文版） 年份：2022
Synchronization is a process that describes the coherent dynamics of a large ensemble of interacting units.The study of explosive synchronization transition attracts considerable attention.Here,I report the explosive transition within the f......
[期刊论文] 作者：Shen Lei,
来源：城市规划（英文版） 年份：2022
1.BackgroundrnThe 14th Five-Year Plan period is a critical period for China to achieve carbon peaking.From the perspective of end users of carbon emis-sions,about 80％are concentrated in cities,which makes the con-struction of eco-cities the ......
Two-dimensional finite element modeling of seepage-erosion coupled process within unsaturated soil s
[期刊论文] 作者：LEI Xiao-qin,
来源：山地科学学报（英文版） 年份：2022
Fines migration along with rainfall infiltration is a possible cause of failures of slopes composed of loose deposits.To investigate the intrinsic mechanisms,a rigid mathematical model which can fully capture the multi-phasic and multi-phys......
[期刊论文] 作者：CHEN Wenyu,SHAO Lei,LEI Humin,
来源：系统工程与电子技术（英文版） 年份：2022
The cooperative interception trajectories generation of multiple interceptors to hypersonic targets is studied.First,to solve the problem of on-line trajectory generation of the single interceptor,a generation method based on neighborhood o......
[期刊论文] 作者：Lei Bao,Xiao-Chen Bo,Huai-Wen Cao,Chen Qian,Zeng Wang,Bin Li,
来源：动物学研究 年份：2022
Chimeric antigen receptor T cells(CAR-T cells)are engineered recombinant T cells,which were initially used to treat hematopoietic malignancies and are now widely used in the treatment of various diseases.Considering their intrinsic targetin......
[期刊论文] 作者：Hui Wang,Wenchang Qian,Yingli Han,Pengxu Qian,
来源： 年份：2022
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[期刊论文] 作者：Qian Hao,Xiang Zhou,
来源：癌症生物学与医学（英文版） 年份：2022
The RNA component of mitochondrial RNA-processing endoribonuclease (RMRP) was first described as an entity that cleaved mitochondrial RNA at a priming site of mito-chondrial DNA replication. This long noncoding RNA (lncRNA) was encoded by a......
[期刊论文] 作者：Qian Zhang,Ye Tian,
来源：遗传学报 年份：2022
There is accumulating evidence to show that environmental stressors can regulate a variety of phenotypes in descendants through germline-mediated epigenetic inheritance.Studies of model organisms exposed to environmental cues(e.g.,diet,heat......
[期刊论文] 作者：Wei-Qiang Ma,Yi-Bin Qian,
来源：中国物理C（英文版） 年份：2022
The isospin dependence of spin-orbit (SO) splitting becomes increasingly important as N/Z increases in neutron-rich nuclei.Following the initial independent-particle strategy toward explaining the occurrence of magic numbers,we systematical......
Asymptotics of the solution to a stationary piecewise-smooth reaction-diffusion equation with a mult
[期刊论文] 作者：Qian Yang,Mingkang Ni,
来源：中国科学：数学（英文版） 年份：2022
A piecewise-smooth second-order singularly perturbed differential equation whose right-hand side is a nonlinear function with a discontinuity on some curve is investigated.This is a new class of problems in the case where the degenerate equ......
[期刊论文] 作者：Li-li SONG,Lei SUN,
来源：应用数学学报（英文版） 年份：2022
A graph is 1-planar if it can be drawn on the Euclidean plane so that each edge is crossed by at most one other edge.A proper vertex k-coloring of a graph G is defined as a vertex coloring from a set of k colors such that no two adjacent ve......
Character of cell-free genomic DNA in embryo culture medium and the prospect of its clinical applica
[期刊论文] 作者：Lei Cai-Xia,Sun Xiao-Xi,
来源：生殖与发育医学（英文） 年份：2022
There is increasing evidence that cell-free DNA (cfDNA) in spent culture media (SCM) can be amplified for genetic testing. Therefore, this paper reviews the characteristics of cfDNA, including its fragment size, amount, origin, as well as s......
[期刊论文] 作者：Yunzhe Li,Lei Tian,
来源：光：科学与应用（英文版） 年份：2022
Diffractive Deep Neural Network enables computer-free, all-optical“computational imaging”for seeing through unknown random diffusers at the speed of light....
[期刊论文] 作者：Shi Jin,Lei Li,
来源：中国科学：数学（英文版） 年份：2022
The Random Batch Method proposed in our previous work (Jin et al.J Comput Phys,2020) is not only a numerical method for interacting particle systems and its mean-field limit,but also can be viewed as a model of the particle system in which ......
A long-range forecasting model for the thermosphere based on the intelligent optimized particle filt
[期刊论文] 作者：Dexin REN,Jiuhou LEI,
来源：中国科学：地球科学（英文版） 年份：2022
The uncertainties associated with the variations in the thermosphere are responsible for the inaccurate prediction of the orbit decay of low Earth orbiting space objects due to the drag force.Accurate forecasting of the thermosphere is urge......
Influence of two polyphenols on the structure and lubrication of salivary pellicle: An in vitro stud
[期刊论文] 作者：Lei LEI,Yue TANG,Jing ZHENG,Genlei MA,Zhongrong ZHOU,
来源：摩擦（英文版） 年份：2022
This study investigated the influence of two polyphenols on the structure and lubrication of the salivary pellicle, aiming to extend the understanding of astringency mechanisms. The salivary pellicle was prepared by the adsorption of human ......
[期刊论文] 作者：Lei Sheng,Jing Gao,Qian Xu,Xue Zhang,Miao Huang,Xin Dai,Song Li,刘联,
来源：中华肿瘤防治杂志 年份：2022
背景 免疫检查点抑制剂(ICI)可改善晚期野生型非小细胞肺癌(NSCLC)患者的生存,但缺乏对多种一线治疗直接比较的证据,这对临床决策的制定不利.为此,本研究通过网状荟萃分析对比了现有的一线治疗模式,旨在确定具有特定病理学特征患者的最佳治疗方案.方法 系统检索......
Seed dormancy,germination and storage behavior of Magnolia sinica,a plant species with extremely sma
[期刊论文] 作者：Liang Lin,Lei Cai,Lei Fan,Jun-Chao Ma,Xiang-Yun Yang,Xiao-Jian Hu,
来源：植物多样性（英文版） 年份：2022
Magnolia sinica is one of the most endangered Magnoliaceae species in China.Seed biology information concerning its long-term ex situ conservation and utilization is insufficient.This study investigated dormancy status,germination requireme......
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