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Genistein enhances amyloid-β 42 clearance across blood-brain barrier by inducing P-glycoprotein in v
[会议论文] 作者：NIU Fang,ZHOU Fang,WU Xiao-lan,ZHANG Jing-wei,WANG Guang-ji,
来源：第十届全国药物和化学异物代谢学术会议暨第三届国际ISSX/CSSX联合学术会议 年份：2012
Objective Genistein is a good candidate as an alternative to estrogen replacement therapy for Aizheimer disease (AD)because of the effects in ameliorating learning or memory deficits of AD without inc...
Synergetic effect of 20(S)-ginsenoside Rh2 on ciprofloxacin: investigation on the function of efflux
[会议论文] 作者：SUN Yuan,ZHOU Fang,ZHA Wei-bin,ZHANG Jing-wei,WANG Guang-ji,
来源：第十届全国药物和化学异物代谢学术会议暨第三届国际ISSX/CSSX联合学术会议 年份：2012
Objective Bacterial drag resistance caused by effiux pump remains problematic.Our previous study showed that 20 (S)-ginsenoside Rh2 (20 (S)-Rh2) reversed multidrug resistance (MDR) in MCF-7 cells by i...
Development and validation of an improved LC-MS/MS method for simultaneous quantitation of metformin
[会议论文] 作者：ZHANG Xue-yuan,PENG Ying,SUN Jian-guo,WAN Ping,YIN Li-fang,WANG Guang-ji,
来源：第十届全国药物和化学异物代谢学术会议暨第三届国际ISSX/CSSX联合学术会议 年份：2012
Objective To support the pharmacokinetic study of metformin (MET) hydroehloride/pioglitazone (PIO) hydroehloride tablet, an LC-MS/MS method was developed for the simultaneous determination of MET and...
The Pharmacokinetic-Pharmacodynamic Model of Azithromycin for Lipopolysaccharide-Induced Depressive-
[会议论文] 作者：HAO Kun,QI Qu,HAO Hai-Ping,WANG Guang-Ji,CHEN Yuan-Cheng,LIANG Yan,XIE Lin,
来源：第十届全国药物和化学异物代谢学术会议暨第三届国际ISSX/CSSX联合学术会议 年份：2012
A mechanism-based model was developed to describe the time course of lipopolysaccharide-induced depressive-like behavior and azithromycin pharmacodynarnics in mice.The lipopolysacchatide-induced disea...
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