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[期刊论文] 作者：Songbo Tang,Zhijian MOU,Oliver L.Phillips,Hans Lambers,Zhanfeng Liu,Jordi Sardans,Josep Pe(n)uelas,Yuan Lai,
来源：植物生态学报（英文版） 年份：2021
了解优势树种叶片多水平的功能性状沿海拔梯度的变化及其内在关联,有助于预测优势种应对气候变化的响应与适应.本文研究了青冈属树种叶片气孔、解剖和形态性状沿海拔梯度的变化及其与环境调控因子的关联,探究了其生态策略是否随海拔发生改变.在海南尖峰岭热带森......
[期刊论文] 作者：Xuelei Lai,Romain Blanc-Mathieu,Lo?,
来源：分子植物（英文版） 年份：2021
Pioneer transcription factors(TFs)are a special category of TFs with the capacity to bind to closed chro-matin regions in which DNA is wrapped around histones a...
Pharmacokinetics,mass balance,and metabolism of[14C]vicagrel,a novel irreversible P2Y12 inhibitor in
[期刊论文] 作者：Yuan-dong Zheng,Hua Zhang,Yan Zhan,Yi-cong Bian,Sheng Ma,Hai-xian Gan,Xiao-juan Lai,Yong-qiang Liu,Yan-chun,
来源：中国药理学报（英文版） 年份：2021
Vicagrel,a novel irreversible P2Y12 receptor inhibitor,is undergoing phase Ⅲ trials for the treatment of acute coronary syndromes in China.In this study,we evaluated the pharmacokinetics,mass balance,and metabolism of vicagrel in six healt......
Treatment of secondary central nervous system involvement in systemic aggressive B cell lymphoma usi
[期刊论文] 作者：Wu Yuchen,Sun Xuefei,Bai Xueyan,Qian Jun,Zhu Hong,Cui Qu,Xing Ruixian,Chen Yuedan,Liu Qing,Lai Wenyuan,
来源：中华神经外科杂志（英文） 年份：2021
Background::Secondary central nervous system lymphoma (SCNSL) is defined as lymphoma involvement within the central nervous system (CNS) that originated elsewhe...
Induction of Wnt signaling antagonists and p21-activated kinase enhances cardiomyocyte proliferation
[期刊论文] 作者：Xiangwen Peng,Kaa Seng Lai,Peilu She,Junsu Kang,Tingting Wang,Guobao Li,Yating Zhou,Jianjian Sun,Daqing,
来源：分子细胞生物学报（英文版） 年份：2021
Heart regeneration occurs by dedifferentiation and proliferation of pre-existing cardiomyocytes (CMs).However,the signaling mechanisms by which injury induces C...
Designer uniform Li plating/stripping through lithium-cobalt alloying hierarchical scaffolds for sca
[期刊论文] 作者：Weiqiang Tang,Hui Luo,Yan Zhao,Rui Tan,Mo Qiao,Xinlei Gao,Yang Hua,Huizhi Wang,Shuangliang Zhao,Chao Lai,
来源：能源化学 年份：2021
Lithium metal anodes are of great interest for advanced high-energy density batteries such as lithium-air,lithium-sulfur and solid-state batteries,due to their...
[期刊论文] 作者：Mingliang Ma,Huan Qi,Chuansheng Hu,Zhaowei Xu,Fanlin Wu,Nan Wang,Danyun Lai,Yang Li,Hainan Zhang,Hewei,
来源：生物化学与生物物理学报（英文版） 年份：2021
PD-1 plays an important role as an immune checkpoint.Sintilimab is a newly approved PD-1 antibody for cancer immunotherapy with an unknown binding epitope on PD...
Antibody upstream sequence diversity and its biological implications revealed by repertoire sequenci
[期刊论文] 作者：Haipei Tang,Qilong Wang,Junjie Guan,Wenxi Xie,Sen Chen,Yuan Chen,Minhui Wang,Chunhong Lan,Deqiang Sun,Lai,
来源：遗传学报 年份：2021
The sequence upstream of the antibody variable region (antibody upstream sequence[AUS]) consists of a 5\'untranslated region (5\'UTR) and a preceding leader region.The sequence variations in AUS affect antibody engineering end PCR based ant......
Identification of optimal contemporary antiemetic prophylaxis for doxorubicin-cyclophosphamide chemo
[期刊论文] 作者：Winnie Yeo,Leung Li,Thomas KH Lau,Kwai T Lai,Vicky,TC Chan,Kwan H Wong,Christopher CH Yip,Elizabeth Pang,
来源：癌症生物学与医学:英文版 年份：2021
Objective:Chemotherapy-induced nausea and vomiting(CINV)are common with doxorubicin-cyclophosphamide(AC)chemotherapy.Recommended antiemetic regimens incorporate neurokinin-1 receptor antagonist(NK1 RA),5-hydroxytryptamine type-3 receptor an......
Early development and functional properties of tryptase/chymase double-positive mast cells from huma
[期刊论文] 作者：Guohui Bian,Yanzheng Gu,Changlu Xu,Wenyu Yang,Xu Pan,Yijin Chen,Mowen Lai,Ya Zhou,Yong Dong,Bin Mao,Qiongxiu,
来源：分子细胞生物学报（英文版） 年份：2021
Mast cells (MCs) play a pivotal role in the hypersensitivity reaction by regulating the innate and adaptive immune responses.Humans have two types of MCs.The fi...
A teosinte-derived allele of a MYB transcription repressor confers multiple disease resistance in ma
[期刊论文] 作者：Dai,Jiamin Que,Haoxuan Min,Gengshen Chen,Yanbo Wang,Min Jiang,Yan Liang,Lin Li,Xuecai Zhang,Zhibing Lai,
来源：分子植物（英文版） 年份：2021
Natural alleles that control multiple disease resistance (MDR) are valuable for crop breeding.However,only one MDR gene has been cloned in maize,and the molecular mechanisms of MDR remain unclear in maize.In this study,through map-based clo......
[期刊论文] 作者：Siqi Lu,Lin Xie,Kang Lai,Runkun Chen,Lu Cao,Kuojuei Hu,Xuefeng Wang,Jinsen Han,Xiangang Wan,Jianguo Wan,
来源：国家科学评论（英文版） 年份：2021
The plasmonic response of gold dusters with atom number (N) =100-70000 was investigated using scanning transmission electron microscopy-electron energy loss spectroscopy.For decreasing N,the bulk plasmon remains unchanged above N =887 but t......
[期刊论文] 作者：Jie Xu,Shuhua Lai,Defeng Qi,Min Hu,Xianyun Peng,Yifan Liu,Wei Liu,Guangzhi Hu,Heng Xu,Fan Li,Chao Li,,
来源：纳米研究（英文版） 年份：2021
An effective electrocatalyst being highly active in all pH range for oxygen reduction reaction (ORR) is crucial for energy conversion and storage devices.Howeve...
Improving the Cpf1-mediated base editing system by combining dCas9/dead sgRNA with human APOBEC3A va
[期刊论文] 作者：Yanhui Liang,Jingke Xie,Weikai Ge,Zhenpeng Zhuang,Jiaowei Wang,Yinghua Ye,Yi Yang,Kepin Wang,Liangxue Lai,
来源：遗传学报 年份：2021
Base editor-mediated C-to-T base conversion obviates the re-quirements of double-strand breaks,thereby showing promise as a tool for disease modeling and gene t...
A simple and easily implemented risk model to predict 1-year ischemic stroke and systemic embolism i
[期刊论文] 作者：Jiang Chao,Chen Tian-Ge,Du Xin,Li Xiang,He Liu,Lai Yi-Wei,Xia Shi-Jun,Liu Rong,Hu Yi-Ying,Li Ying-Xue,
来源：中华医学杂志英文版 年份：2021
Background::Accurate prediction of ischemic stroke is required for deciding anticoagulation use in patients with atrial fibrillation (AF). Even though only 6% to 8% of AF patients die from stroke, about 90% are indicated for anticoagulants ......
Targeted Micellar Phthalocyanine for Lymph Node Metastasis Homing and Photothermal Therapy in an Ort
[期刊论文] 作者：Hai‑Yi Feng,Yihang Yuan,Yunpeng Zhang,Hai‑Jun Liu,Xiao Dong,Si‑Cong Yang,Xue‑Liang Liu,Xing Lai,Mao‑Hua,
来源：纳微快报:英文版 年份：2021
Tumor lymph node(LN)metastasis seriously affects the treatment prognosis.Studies have shown that nanoparticles with size of sub-50 nm can directly penetrate into LN metastases after intravenous administration.Here,we speculate through intro......
[期刊论文] 作者：Suoyi Tan,Shengjie Lai,Fan Fang,Ziqiang Cao,Bin Sai,Bing Song,Bitao Dai,Shuhui Guo,Chuchu Liu,Mengsi,
来源：国家科学评论（英文版） 年份：2021
2020 was an unprecedented year,with rapid and drastic changes in human mobility due to the COVID-19 pandemic.To understand the variation in commuting patterns among the Chinese population across stable and unstable periods,we used nationwid......
Targeted Micellar Phthalocyanine for Lymph Node Metastasis Homing and Photothermal Therapy in an Ort
[期刊论文] 作者：Liang Liu,Xing Lai,Mao?Hua Zhu1,Jue Wang,Qin Lu,Quanjun Lin,Hong?Zhuan Chen,Jonathan F.,
来源：纳微快报（英文版） 年份：2021
Tumor lymph node (LN) metastasis seriously affects the treatment prognosis. Studies have shown that nanoparticles with size of sub-50 nm can directly penetrate into LN metastases after intravenous administration. Here, we speculate through ......
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