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Single-cell RNA-seq and chromatin accessibility profiling decipher the heterogeneity of mouse γδ T c
[期刊论文] 作者：Shanshan Wang,Xiaojie Qi,Yawen Zhang,Zonghua Liu,Jing Luo,Hui Liu,Yongbing Ba,Lianxia Guo,Baojian Wu,Fang Huang,
来源：科学通报（英文版） 年份：2022
The distinct characteristics of γδ T cells determine their vital roles in the formation of local immune responses and contribute to tissue homeostasis.However,the heterogeneity of γδ T cells across tissues remains unclear.By combining t......
[期刊论文] 作者：Changsheng Wang,Yongyao Xie,Zhihua Zhang,Jiaxin Chen,Letian Chen,Chengcai Chu,Guangcun He,Zuhua He,Xuehui Huang,
来源：中国科学：生命科学（英文版） 年份：2022
Rice (Oryza sativa L.) is one of the most important crops in the world.Since the completion of rice reference genome sequences,tremendous progress has been achieved in understanding the molecular mechanisms on various rice traits and dissec......
[期刊论文] 作者：Yang Ou,Brad A.Clifton,Jinghui Li,David Sandlin,Na Li,Li Wu,Chunming Zhang,Tianwen Chen,Jun Huang,Yue,
来源：中国神经再生研究（英文版） 年份：2022
Exposure to explosive shockwave often leads to blast-induced traumatic brain injury in military and civilian populations. Unprotected ears are most often damaged following exposure to blasts. Although there is an association between tympani......
[期刊论文] 作者：Yang Hao,Yu-Zhen Zhou,Bin Chen,Gui-Zhen Chen,Zhen-Ying Wen,Diyang Zhang,Wei-Hong Sun,Ding-Kun Liu,Jie Huang,
来源：遗传学报 年份：2022
Melastomataceae has abundant morphological diversity with high economic and ornamental merit in Myrtales.The phylogenetic position of Myrtales is still contested.Here,we report the chromosome-level genome assembly of Melastoma dodecandrum i......
Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomi
[期刊论文] 作者：Suwei Gao,Qiang Shi,Yifan Zhang,Guixian Liang,Zhixin Kang,Baofeng Huang,Dongyuan Ma,Lu Wang,Jianwei Jiao,
来源：细胞研究（英文版） 年份：2022
Limited knowledge of cellular and molecular mechanisms underlying hematopoietic stem cell and multipotent progenitor (HSC/MPP)expansion within their native niche has impeded the application of stem cell-based therapies for hematological mal......
[期刊论文] 作者：Xiao-ru Zhou,Xiao Li,Li-ping Liao,Jie Han,Jing Huang,Jia-cheng Li,Hong-ru Tao,Shi-jie Fan,Zhi-feng Chen,
来源：中国药理学报（英文版） 年份：2022
Mantle cell lymphoma(MCL)is a lymphoproliferative disorder lacking reliable therapies.PI3K pathway contributes to the pathogenesis of MCL,serving as a potential target.However,idelalisib,an FDA-approved drug targeting PI3Kδ,has shown intri......
[期刊论文] 作者：Deng,Yajie Du,Daojin Fan,Ming Gong,Cheng Guo,Chu Guo,Shaojun Guo,Lianchen Han,Linyin Hong,He-Liang Huang,
来源：科学通报（英文版） 年份：2022
To ensure a long-term quantum computational advantage,the quantum hardware should be upgraded to withstand the competition of continuously improved classical algorithms and hardwares.Here,we demonstrate a superconducting quantum computing s......
Metabolic Dysfunction-associated Fatty Liver Disease is Associated with Greater Impairment of Lung F
[期刊论文] 作者：Yang Chen,Huai Zhang,Hui Cai,Zhi-Wei Xu,Shuan-Ying Yang,Hai Lin,Zhe Cheng,Ming-Yang Zhu,Xu Nan,Shuai Huang,
来源：临床与转化肝病杂志（英文版） 年份：2022
Background and Aims: We compared lung function parameters in nonalcoholic fatty liver disease (NAFLD) and metabolic dysfunction-associated fatty liver disease (MAFLD), and examined the association between lung function parameters and fibros......
Targeting a cryptic allosteric site of SIRT6 with small-molecule inhibitors that inhibit the migrati
[期刊论文] 作者：Qiufen Zhang,Yingyi Chen,Duan Ni,Zhimin Huang,Jiacheng Wei,Li Feng,Jun-Cheng Su,Yingqing Wei,Shaobo Ning,
来源：药学学报（英文版） 年份：2022
SIRT6 belongs to the conserved NAD+-dependent deacetylase superfamily and mediates multiple biological and pathological processes.Targeting SIRT6 by allosteric modulators represents a novel direction for therapeutics,which can overcome the ......
[期刊论文] 作者：Yang,Hua-Yong Wu,Jing Zhang,De-Cheng Li,Feng Liu,Yu-Guo Zhao,Jin-Ling Yang,Bing Ju,Chong-Fa Cai,Biao Huang,
来源：国家科学评论（英文版） 年份：2022
Widespread soil acidification due to atmospheric acid deposition and agricultural fertilization may greatly accelerate soil carbonate dissolution and CO2 release.However,to date,few studies have addressed these processes.Here,we use meta-an......
[期刊论文] 作者：Song,Xiao Guo,Yong-Song Wang,He Ma,Yin-Zou Zhao,Fan-Ying Wu,Shu-Yu Liu,Kai-Hui Liu,Ya-Hua Yuan,Han Huang,
来源：中国物理B（英文版） 年份：2022
High-quality large 1T phase of TiX2(X=Te,Se,and S)single crystals have been grown by chemical vapor transport using iodine as a transport agent.The samples are characterized by compositional and structural analyses,and their proper-ties are......
[期刊论文] 作者：Zuqiang Wang,Hangang Chen,Qiaoyan Tan,Junlan Huang,Siru Zhou,Fengtao Luo,Dali Zhang,Jing Yang,Can Li,,
来源：骨研究（英文版） 年份：2022
INTRODUCTIONrnLow back pain (LBP) is a debilitating condition that affects～84％of the population in their lifetime.1 LBP affects physical function, reduces quality of life, and causes psychological distress.2 Although LBP is a multifactorial d......
Formation of multifaceted nano-groove structure on rutile TiO2 photoanode for efficient electron-hol
[期刊论文] 作者：Yaling Luo,Ziyu Wang,Yao Xiang,Zheng Peng,Yong Han,Hui Zhang,Ruotian Chen,Qin Zhou,Hongru Peng,Hao Huang,
来源：能源化学 年份：2022
Photoelectrochemical (PEC) water-splitting using solar energy holds great promise for the renewable energy future,and a key challenge in the development of industry viable PEC devices is the unavailability of high-efficient photoanodes.Here......
[期刊论文] 作者：Cheng Wang,Mingtao Huang,Congcong Chen,Yuancheng Li,Na Qin,Zijian Ma,Jingyi Fan,Linnan Gong,Hui Zeng,,
来源：中国科学：生命科学（英文版） 年份：2022
Adenosine-to-inosine (A-to-I) RNA editing is a widespread posttranscriptional modification that has been shown to play an important role in tumorigenesis.Here,we evaluated a total of 19,316 RNA editing sites in the tissues of 80 lung adenoc......
[期刊论文] 作者：ZHOU Xian Long,DING Guo Yong,YANG Lu Yu,LIU Rui Ning,HOU Hai Feng,WANG Ping,MA Min,HU Zhuan Zhuan,HUANG,
来源：生物医学与环境科学（英文版） 年份：2022
Coronavirus disease 2019 (COVID-19) has inarguably caused the most challenging pandemic. In less than 2 years, greater than 200 million cases of COVID-19 and 4.5 million deaths have been reported worldwide[1]....
[期刊论文] 作者：Zhenjiang Bai,Qing Li,Qinghui Chen,Changming Niu,Yu Wei,Hanpeng Huang,Wei Zhao,Nian Chen,Xin Yao,Qiang,
来源： 年份：2022
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[期刊论文] 作者：Yahui Liu,Bowen Liu,Chang-Qi Ma,Fei Huang,Guitao Feng,Hongzheng Chen,Jianhui Hou,Lingpeng Yan,Qingya,
来源：中国科学：化学（英文版） 年份：2022
During past several years,the photovoltaic performances of organic solar cells(OSCs)have achieved rapid progress with power conversion efficiencies(PCEs)over 18％,demonstrating a great practical application prospect.The development of materia......
[期刊论文] 作者：Kun YANG,Tao LAN,Chen CHEN,Jie WU,Sen ZHANG,Wenzhe MAO,Zhihao ZHAO,Fanwei MENG,Xiaohui ZHANG,Yanqing HUANG,
来源：等离子体科学和技术（英文版） 年份：2022
Compact torus(CT)injection is one of the most promising methods for the central fuelling of next-generation reactor-grade fusion devices due to its high density,high velocity,and self-contained magnetised structure.A newly compact torus inj......
[期刊论文] 作者：Kui Wang,Na Li,Jingwei Feng,Jing Wen,Shipeng Cheng,Yaguang Zhang,Weiwei Yang,Dan Ye,Zhimin Lu,Canhua Huang,
来源：中国科学：生命科学（英文版） 年份：2022
The changes associated with malignancy are not only in cancer cells but also in environment in which cancer cells live.Metabolic reprogramming supports tumor cells\'high demand of biogenesis for their rapid proliferation,and helps tumor cel......
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