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Nintedanib (BIBF 1120)+docetaxel in NSCLC patients progressing after first line chemotherapy: LUME L
[会议论文] 作者：Reck M,Kaiser R,Gaschler-Markefski B,Mellemgaard A,Douillard J-Y,Orlov S,Krzakowski M,von Pawel J,Gottfried,
来源：第十六届全国临床肿瘤学大会暨2013年CSCO学术年会 年份：2013
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Nintedanib (BIBF 1120)+docetaxel in NSCLC patients progressing after first line chemotherapy: LUME L
[会议论文] 作者：Douillard J-Y,Orlov S,Krzakowski M,von Pawel J,Gottfried M,Bondarenko I,Barrueco J,Gaschler-Markefski B,,
来源：第十六届全国临床肿瘤学大会暨2013年CSCO学术年会 年份：2013
Objective: Nintedanib (N) inhibits VEGFRs, PDGFRs and FGFRs.LUME Lung 1 is a placebo (P) controlled phase 3 trial of N+docetaxel (D) in patients (pts) with locally advanced/metastatic NSCLC progressin...
Bone morphogenetic protein-4 mediates cardiac hypertrophy,apoptosis,and fibrosis in experimentally p
[会议论文] 作者：Sun B,Guo WT,Zhu JX,Yang BF,Dong DL,Huo R,Sheng Y,Li Y,Xie X,Chen C,Liu HB,Li N,Li CB,
来源：第15届中国南方国际心血管病学术会议 年份：2013
...
Distinct effector secretion systems and biotrophic invasion by the rice blast fungus, Magnaporthe or
[会议论文] 作者：B Valent,X Wang,R Terauchi,JY Lee,NJ Talbot,MC Giraldo,M Yi,CH Khang,Y Dagdas,Y Gupta,T Mentlak,M Dalby,
来源：The Second Beijing International Symposium on Molecular Plan 年份：2013
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[会议论文] 作者：DJ Bertioli,T Schwarzacher,AH Paterson,P Heslop-Harrison,ACG Araujo,B Vidigal,S Nielen,MB Ratnaparkhe,
来源：The Sixth International Conference of the Peanut Research Co 年份：2013
Here we report an analysis of the repetitive component of peanuts A genome using BAC clones from A.duranensis, peanuts most probable A genome donor.Analyses were done using fluorescent in situ hybridi...
[期刊论文] 作者：Bénédicte Jacquemin,Johanna Lepeule,Anne Boudier,Caroline Arnould,Meriem Benmerad,Claire Chappaz,Joane,
来源：环境与职业医学 年份：2013
[背景]地址地理编码中的错误可能会影响空气污染对健康影响的估计。[目的]研究4种地理编码技术对采用小尺度(10m×10m)分散模型估计的城市空气污染与成人肺功能之间关联的影响。[方法]测量法国格勒诺布尔市354名成年居民的1秒用力呼气容积(FEV1)与用力肺活量(FV......
[会议论文] 作者：Zhang Y,Ming ZJ,Kai Lee Yap,Wang JR,Ie-Ming Shih,Yang JM,Cheng Y,Zhang L,Shan Y,Ren YJ,Ren XC,Chen B,,
来源：江苏省药理学会青年工作委员会成立大会暨药理学科青年科技创新学术研讨会 年份：2013
Tumor hypoxia is associated with cancer progression, but the hypoxia signaling mechanism remains largely unclear.Here, we show that Nucleus accumbens-1 (NAC1), a nuclear factor belonging to the BTB/PO...
Analysis of KRAS/NRAS and BRAF Mutations in the Phase 3 PRIME Study of Panitumumab+FOLFOX4 vs.FOLFOX
[会议论文] 作者：Humblet,Gyorgy Bodoky,David Cunningham,Jacek Jassem,Fernando Rivera,Ilona Kocákova,Paul Ruff,Maria B,
来源：第十六届全国临床肿瘤学大会暨2013年CSCO学术年会 年份：2013
Background: Analysis of a phase 3 panitumumab monotherapy study suggested that KRAS and NRAS mutations beyond KRAS exon 2 may be predictive of panitumumab efficacy (Peeters M,et al.Clin Cancer Res 201...
[期刊论文] 作者：Charles B Simone II,Joseph S Friedberg,Eli Glatstein,James P Stevenson,Daniel H Sterman,Stephen M Hahn,
来源：国际病理科学与临床杂志 年份：2013
光动力疗法被越来越多地应用于治疗胸部恶性肿瘤。对于早期非小细胞肺癌(如支气管腔内肺癌)、X线检查阴性或同时性原发癌,光动疗法可作为主要治疗手段进行腔内根治性治疗。作...
[期刊论文] 作者：Bazzoli E,Pulvirenti T,Oberstadt MC,Perna F,Wee B,Schultz N,Huse JT,Fomchenko EI,Voza F,Tabar V,Brennan,
来源：中国神经肿瘤杂志 年份：2013
High-grade gliomas are aggressive and uniformly fatal tumors,composed of a heterogeneous population of cells that include many with stem-cell-like properties.Th...
[会议论文] 作者：Sandra Reuter,Michael B Prentice,Brendan W Wren,Julian Parkhill,Elisabeth Carniel,Mark Achtman,Alan McNally,
来源：The 11th International Symposium on Yersinia(第11届国际鼠疫研讨会) 年份：2013
The genus Yersinia has been used as a model system to study pathogen evolution.Using whole genome sequencing of all Yersinia species we delineate the gene compl...
[会议论文] 作者：Humblet,Gyorgy Bodoky,David Cunningham,Jacek Jassem,Fernando Rivera,Ilona Kocákova,Paul Ruff,Maria B,
来源：第十六届全国临床肿瘤学大会暨2013年CSCO学术年会 年份：2013
目的: The primary and final analyses of PRIME demonstrated that panitumumab+FOLFOX4 significantly improved progression-free survival (PFS) vs.FOLFOX4 alone for 1st-line treatment of patients with wild-t...
[会议论文] 作者：Z-T Tong,J-H Wei,J-X Zhang,C-Z Liang,B Liao,J Lu,S Fan,Z-H Chen,F Zhang,H-H Ma,W-C Qian,L-L Kong,Y Fang,
来源：2013年广东省医学会泌尿外科学学术年会 年份：2013
Background:We previously demonstrated that AIB1 overexpression is an independent molecular marker for shortened survival of bladder cancer (BC) patients.In this study,we characterised the role and mol...
[会议论文] 作者：王崇元,滕脉坤,吴季辉,Joan M Hevel,施蕴渝,朱玉威,Tamar B Caceres,彭俊辉,王军成,陈佳婧,陈旭文,张志勇,龚庆国,
来源：2013年第四届全国“跨学科蛋白质研究”学术讨论会 年份：2013
Arginine methylation plays vital roles in numerous biological processes, such as transcription regulation, RNA processing, DNA repair and signal transductio...
Interlaboratory validation for the in vivo flow cytometric micronucleus analysis method (MicroFlow (
[会议论文] 作者：XIA Z,ZHONG Z,ZHANG M,AN F,CAO Y,GENG X,JIAMG Y,JU Q,YU Y,ZHU J,ZHOU C,SD DERTINGER,LIB,LIAO M,YUAN B,,
来源：中国毒理学会第六届全国毒理学大会 年份：2013
Although inter-laboratory validation efforts of the flow cytometry (FCM) based in vivo micronucleus (MN) assay have taken place in the EU and US, none have been organized in China.Therefore a high pro...
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