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Phase I dose-escalation and expansion study of PARP inhibitor, fluzoparib (SHR3162), in patients wit
[期刊论文] 作者：Huiping Li,Rongrui Liu,Bin Shao,Ran Ran,Guohong Song,Ke Wang,Yehui Shi,Jihong Liu,Wenjing Hu,Fu Chen,,
来源：中国癌症研究（英文版） 年份：2020
Objective: Fluzoparib (SHR3162) is a novel,potent poly(ADP-ribose) polymerases (PARP)1,2 inhibitor that showed anti-tumor activity in xenograft models.We conduc...
[期刊论文] 作者：Liao,Zhihong Yang,Tarsha Ward,Ke Ruan,Jianchun Zhang,Quan Wu,Ping He,Xia Ding,Dongmei Wang,Chuanhai Fu,
来源：分子细胞生物学报（英文版） 年份：2020
Error-free cell division depends on the accurate assembly of the spindle midzone from dynamic spindle microtubules to ensure chromatid segregation during metaph...
Science and Prediction of Heavy Rainfall over China: Research Progress since the Reform and Opening-
[期刊论文] 作者：Shuai YANG,Yuanchun ZHANG,Jing CHEN,Kan DAI,Xueshun SHEN,Haoming CHEN,Feifan ZHOU,Yimin LIU,Shenming FU,
来源：气象学报（英文版） 年份：2020
This paper reviews the major progress on development of the science and prediction of heavy rainfall over China since the beginning of the reform and opening-up...
[期刊论文] 作者：LIU William,WANG Chi,SHEN Xuhui,WU Jian,BLANC Michel,YAN Yihua,FU Suiyan,YUE Xinan,LEI Jiuhou,GONG Wei,
来源：空间科学学报 年份：2020
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,Frequent RNF43 mutation contributes to moderate activation of Wnt signaling in colorectal signet-ri
[期刊论文] 作者：Yaqi Li,Jian Li,Renjie Wang,Long Zhang,Guoxiang Fu,Xueying Wang,Yebin Wang,Chuantao Fang,Dandan Zhang,
来源：蛋白质与细胞 年份：2020
Dear Editor,Signet-ring cell carcinoma (SRCC) is a rare subtype of colorectal cancer (CRC) characterized histologically by the accumulation of mucins in the cyt...
Genome assembly and transcriptome analysis provide insights into the antischistosome mechanism of Mi
[期刊论文] 作者：Qingyu Xiao,Benpeng Miao,Weili Lin,Jie Feng,Mingyue Huang,Cheng Gao,Bin Li,Wei Hu,Jiaojiao Lin,Zhiqiang Fu,
来源：遗传学报 年份：2020
Microtus fortis is the only mammalian host that exhibits intrinsic resistance against Schistosoma japo-nicum infection.However,the underlying molecular mechanis...
A Chromosome-Level Genome Assembly of Garlic (Allium sativum) Provides Insights into Genome Evolutio
[期刊论文] 作者：Jing Zhao,Xuguang Qiao,Li Lu,Shiqi Liu,Yanzhou Wang,Chan Liu,Benping Li,Wu Guo,Shuang Gao,Zemao Yang,Fu,
来源：分子植物（英文版） 年份：2020
Garlic,an economically important vegetable,spice,and medicinal crop,produces highly enlarged bulbs and unique organosulfur compounds.Here,we report a chromosome...
Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte matur
[期刊论文] 作者：Xue,Zhongyuan Yao,Juanzi Shi,Biaobang Chen,Ling Wu,Lihua Sun,Yao Xu,Zheng Yan,Bin Li,Xiaoyan Mao,Jing Fu,
来源：蛋白质与细胞 年份：2020
Dear Editor,Previously,the Mendelian phenotypes in human oocyte maturation arrest,fertilization failure and early embryonic arrest,are largely underestimated.In...
Allotransplantation of adult spinal cord tissues after complete transected spinal cord injury:long-t
[期刊论文] 作者：Xi Chen,Bai Xu,Dezun Ma,Yannan Zhao,Yan Zhuang,Bing Chen,Xianglin Hou,Jiayin Li,Yudong Cao,Xianyong Fu,
来源：中国科学:生命科学（英文版） 年份：2020
Spinal cord injury(SCI),especially complete transected SCI,leads to loss of cells and extracellular matrix and functional impairments.In a previous study,we tra...
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