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Common mtDNA variations at C5178a and A249d/T6392C/G10310A decrease the risk of severe COVID?19 in a
[期刊论文] 作者：Fu Wang,Fu?Yun Ji,
来源：军事医学研究（英文版） 年份：2022
Background: Mitochondria have been shown to play vital roles during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) development. Currently, it is unclear whether mitochondrial D......
Efficacy of rigosertib, a small molecular RAS signaling disrupter for the treatment of KRAS-mutant c
[期刊论文] 作者：Xinyi Zhou,Qian Xiao,Dongliang Fu,Haochen Zhang,Yang Tang,Jinjie He,Yeting Hu,Xiangxing Kong,Fei Teng,
来源：癌症生物学与医学（英文版） 年份：2022
Objective: Mutant KRAS, the principal isoform of RAS, plays a pivotal role in the oncogenesis of colorectal cancer by constitutively activating the RAF/MEK/ERK and PI3K/AKT pathways. Effective targeted therapies are urgently needed. We inve......
[期刊论文] 作者：Jian-Fei Tong,Zhi-Liang Hu,Xue-Fen Han,Bin Tang,Qian Yu,Rui-Qiang Zhang,Chong-Guang Zhao,Jun Xu,Shi-Nian Fu,
来源：核技术（英文版） 年份：2022
An accelerator-based Boron Neutron Capture Therapy (AB-BNCT) experimental facility called D-BNCT01 has been recently completed and is currently able to generate a high-intensity neutron beam for BNCT-related research.In this study,we perfor......
Stability of Sn-Pb mixed organic-inorganic halide perovskite solar cells:Progress,challenges,and per
[期刊论文] 作者：Weiyin Gao,Yanghua Liu,He Dong,Nan Sun,Tingting Niu,Yingdong Xia,Zhongbin Wu,Lin Song,Chenxin Ran,Li Fu,
来源：能源化学 年份：2022
The exploration of low bandgap perovskite material to approach Shockley-Queisser limit of photovoltaic device is of great significance,but it is still challenging.During the past few years,tin-lead (Sn-Pb) mixed perovskites with low bandgap......
Recombinant protein subunit vaccine booster following two-dose inactivated vaccines dramatically enh
[期刊论文] 作者：Jingwen Ai,Haocheng Zhang,Qiran Zhang,Yi Zhang,Ke Lin,Zhangfan Fu,Jieyu Song,Yuanhan Zhao,Mingxiang Fan,
来源：细胞研究（英文版） 年份：2022
Dear Editor,rnAs of October,2021,SARS-CoV-2 has infected more than 230 million people;promoting roll-out vaccinations could help build herd immunity for the pandemic.However,the waning of antibody in magnitude and decreased protective effic......
[期刊论文] 作者：,Ji-Xuan LIU,Ji ZOU,Bowen CHEN,Haoyang WU,Hejun LI,Shaoming DONG,Jiecai HAN,Xinghong ZHANG,Qiangang FU,
来源：先进陶瓷（英文版） 年份：2022
Ultra-high temperature ceramics(UHTCs)are generally referred to the carbides,nitrides,and borides of the transition metals,with the Group IVB compounds(Zr&Hf)and TaC as the main focus.The UHTCs are endowed with ultra-high melting points,exc......
[期刊论文] 作者：Fei-fei Xu,Hui-min Sun,Run-ping Fang,Lu Zhang,Hui Shi,Xue Wang,Xue-li Fu,Xian-meng Li,Xu-he Shi,Yue Wu,
来源：中国药理学报（英文版） 年份：2022
Programmed death ligand-1(PD-L1)/PD-1 checkpoint extensively serves as a central mediator of immunosuppression.A tumor-promoting role for abundant PD-L1 in several cancers is revealed.However,the importance of PD-L1 and how the PD-L1 expres......
Genomic polymorphisms at the crhr2 locus improve feed conversion efficiency through alleviation of h
[期刊论文] 作者：Chuang Shi,Qiyong Lou,Beide Fu,Junyan Jin,Jianfei Huang,Yao Lu,Xia Jin,Jiangyan He,Gang Zhai,Shouqi Xie,
来源：中国科学：生命科学（英文版） 年份：2022
Improvement in fish feed conversion efficiency (FCE) is beneficial for sustaining global food fish supplies.Here,we show that a set of polymorphisms at locus of the corticotropin releasing hormone receptor 2 (crhr2),which is involved in hyp......
[期刊论文] 作者：Haole Liu,Kangli Tian,Congcong Xia,Panpan Wei,Boyu Xu,Weilai Fu,Yankui Li,Yafeng Li,Liang Bai,Rong Wang,
来源：动物模型与实验医学（英文） 年份：2022
Background : Porcine pancreatic elastase (PPE) is successfully used to induce abdomi-nal aortic aneurysm (AAA) in mice. However, differences between mouse strains in susceptibility to PPE induction have been reported. Kunming mouse is one o......
Silencing miRNA-324-3p protects against cerebral ischemic injury via regulation of the GATA2/A1R axi
[期刊论文] 作者：Wang,Yi-Xiu Wang,Shan-Shan Hong,Yu-Shan Zhong,Ru-Yi Yu,Xin-Lu Wu,Bing-Bing Zhou,Qi-Min Yu,Hai-Feng Fu,
来源：中国神经再生研究（英文版） 年份：2022
Previous studies have suggested that miR-324-3p is related to the pathophysiology of cerebral ischemia, but the mechanism underlying this relationship is unclear. In this study, we found that miR-324-3p expression was decreased in patients ......
Dissecting the genetic basis of maize deep-sowing tolerance by combining association mapping and gen
[期刊论文] 作者：Yang-yang,Demar LYLE,LI Dong-dong,WANG Ping-xi,XU Jia-liang,ZHEN Si-han,LU Jia-wen,PENG Yun-ling,CUI Yu,FU,
来源：农业科学学报（英文版） 年份：2022
Deep-sowing is an important method for avoiding drought stress in crop species, including maize. Identifying candidate genes is the groundwork for investigating the molecular mechanism underlying maize deep-sowing tolerance. This study eval......
[期刊论文] 作者：Jiang Zhong,Tao Wang,Lei Wang,Lele Peng,Shubin Fu,Meng Zhang,Jinhui Cao,Xiang Xu,Junfei Liang,Huilong,
来源：纳微快报（英文版） 年份：2022
Silicon monoxide (SiO) is an attractive anode material for next-generation lithium-ion batteries for its ultra-high theoreti-cal capacity of 2680 mAh -g?1. The studies to date have been limited to electrodes with a rela-tively low mass load......
[期刊论文] 作者：Yuan,YANG Jia Hui,GAO Ming Yue,ZHAO Wei,LI Chun Mei,XIE XiangHong,ZHANG Wei Hong,ZHANG Hua Bing,FANG Fu,
来源：生物医学与环境科学（英文版） 年份：2022
Mitochondria are important intracellular organelles that carry out oxidative phosphorylation, synthesize ATP, and provide energy for cell activities....
[期刊论文] 作者：Chiyuan Miao,Jiaojiao Gou,Bojie Fu,Qiuhong Tang,Qingyun Duan,Zhongsheng Chen,Huimin Lei,Jie Chen,Jiali,
来源：科学通报（英文版） 年份：2022
Reconstruction of natural stream flow is fundamental to the sustainable management of water resources.In China,previous reconstructions from sparse and poor-quality gauge measurements have led to large biases in simulation of the interannua......
Gene-Environment Interactions between Environmental Noise and ApoE4 Causes AD-Like Neuropathology in
[期刊论文] 作者：LI Wen Long,LI Yuan Yuan,LI Yu Xin,FU Yu,HE Xian Zhi,TAO Fei Yan,YOU Ruo Lan,ZHANG Ruo Yu,ZHONG Ming,
来源：生物医学与环境科学（英文版） 年份：2022
Experimental evidence has demonstrated that environmental hazards can induce neurodegeneration such as Alzheimer\'s disease (AD)[1]. The pathogenesis of AD, characterized by a gradual cognitive decline, overproduction of β-amyloid (Aβ), a......
[期刊论文] 作者：LU ZhiChao,PENG XiangYang,TANG YuHai,HAN ShuYin,WU Yuan,FU EnGang,DING XiangBin,HOU Shuo,LU GuangYao,,
来源：中国科学：技术科学（英文版） 年份：2022
Lead-bismuth eutectics(LBE)have considerable potential as a candidate material for accelerator-driven sub-critical systems(ADS).However,LBE corrosion and irradiation damage are two urgent challenges remaining to be solved for impellers of p......
Role of microtubule dynamics in Wallerian degeneration and nerve regeneration after peripheral nerve
[期刊论文] 作者：Jingmin Liu,Lixia Li,Ying Zou,Lanya Fu,Xinrui Ma,Haowen Zhang,Yizhou Xu,Jiawei Xu,Jiaqi Zhang,Mi Li,Xiaofang,
来源：中国神经再生研究（英文版） 年份：2022
Wallerian degeneration, the progressive disintegration of distal axons and myelin that occurs after peripheral nerve injury, is essential for creating a permissive microenvironment for nerve regeneration, and involves cytoskeletal reconstru......
[期刊论文] 作者：Mingliang Yang,Ying Zhao,Xiaoxia Wu,Chunyan Liu,Candong Li,Xue Yang,Zhendong Zhu,Qingshan Chen,Yongfu Fu,
来源：作物学报（英文版） 年份：2022
Phytophthora sojae infection severely impairs soybean production.We previously identified a dirigent protein,GmDRR1(Glycine max Disease Resistant Response 1),that increases soybean resistance to P.sojae.However,the molecular basis of GmDRR1......
Darbepoetin alfa injection versus epoetin alfa injection for treating anemia of Chinese hemodialysis
[期刊论文] 作者：Nan Chen,Changying Xing,Jianying Niu,Bicheng Liu,Junzhou Fu,Jiuyang Zhao,Zhaohui Ni,Mei Wang,Wenhu Liu,
来源： 年份：2022
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Deep learning algorithm using fundus photographs for 10-year risk assessment of ischemic cardiovascu
[期刊论文] 作者：Yanjun Ma,Jianhao Xiong,Yidan Zhu,Zongyuan Ge,Rong Hua,Meng Fu,Chenglong Li,Bin Wang,Li Dong,Xin Zhao,
来源：科学通报（英文版） 年份：2022
Ischemic cardiovascular diseases (ICVD),including ischemic stroke and coronary heart disease,has become the top cause of death in China [1].A 10-year ICVD risk prediction model in Chinese adults has been developed and validated,which involv......
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