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[期刊论文] 作者:Hannah Jones,Gianfranco Alpini,Heather Francis,, 来源:Acta Pharmaceutica Sinica B 年份:2015
This review focuses on various components of bile acid signaling in relation to cholangiocytes. Their roles as targets for potential therapies for cholangiopath...
[期刊论文] 作者:Heather Francis,Shannon Glaser,Gianfranco Alpini,Gene LeSage,, 来源:World Journal of Gastroenterology 年份:2006
Cholangiocytes are exposed to high concentrations of bile acids at their apical membrane. A selective transporter for bile acids, the Apical Sodium Bile Acid Co...
[期刊论文] 作者:Shannon Glaser,Yuyan Han,Heather Francis,Gianfranco Alpini, 来源:肝胆外科与营养 年份:2014
The intrahepatic biliary epithelium is a three-dimensional tubular system lined by cholangiocytes, epithelial cells that in addition to modify ductal bile are a...
[期刊论文] 作者:Matei P Socoteanu,Frank Mott,Gianfranco Alpini,Arthur E Frankel,, 来源:World Journal of Gastroenterology 年份:2008
Cholangiocarcinoma continues to be a challenging disease to treat. Systemic therapy is used in unresectable disease, disease progression after surgery, and in t...
[期刊论文] 作者:Paolo Onori,Eugenio Gaudio,Antonio Franchitto,Gianfranco Alpini,Heather Francis,, 来源:World Journal of Gastrointestinal Pathophysiology 年份:2010
Histamine has long been known to be involved in inflammatory events.The discovery of antihistamines dates back to the first half of the 20th century when a Swis...
[期刊论文] 作者:Candace Wise,Metaneeya Pilanthananond,Benjamin F Perry,Gianfranco Alpini,Michael McNeal,Shannon S Glaser, 来源:World Journal of Gastroenterology 年份:2008
Cholangiocarcinoma is a rare cancer originating from the neoplastic transformation of the epithelial cells (i.e. cholangiocytes) that line the biliary tract. Th...
[期刊论文] 作者:Anastasia Renzi,Romina Mancinelli,Paolo Onori,Antonio Franchitto,Gianfranco Alpini,Shannon Glaser,Eugenio, 来源:肝胆外科与营养 年份:2014
Background and aims: Reduction of biliary serotonin N-acetyltransferase (AANAT) expression and melatonin administration/secretion in cholangiocytes increases bi...
[期刊论文] 作者:Glaser,Heather Francis,Sharon DeMorrow,Gene LeSage,Giammarco Fava,Marco Marzioni,Julie Venter,Gianfranco Alpini, 来源:World Journal of Gastroenterology 年份:2006
The objectives of this review are to outline the recent findings related to the morphological heterogeneity of the biliary epithelium and the heterogeneous path...
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