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Cucurbitacin E induces apoptosis and attenuates activation of hepatic stellate cells via PI_3K/Akt-A
[期刊论文] 作者:You-li YAO,Li-hua LIAN,Shuang JIANG,Ji-xing NAN,Yan-ling WU,,
来源:中国药理学与毒理学杂志 年份:2015
OBJECTIVE Hepatic fibrosis is a wound-healing response for injury.Activated hepatic stellate cells(HSCs)are the preferred targets of anti-hepatic fibrotic thera...
Gentiana manshurica Kitagawa prevents acetaminopheninduced acute hepatic injury in mice via inhibiti
[期刊论文] 作者:Ai-Yan Wang,Li-Hua Lian,Ying-Zi Jiang,Yan-Ling Wu,Ji-Xing Nan,
来源:世界胃肠病学杂志(英文版) 年份:2010
AIM: To investigate the in vivo hepatoprotective effects and mechanisms of Gentiana manshurica Kitagawa (GM) in acetaminophen (APAP)-induced liver injury in mic...
P2X7 receptor inhibitor suppressed extracellular ATP/LPS-primed human hepatic stellate cells activat
[期刊论文] 作者:Shuang JIANG,Quan JIN,Yan-ling WU,You-li YAO,Ji-xing NAN,Li-hua LIAN,,
来源:中国药理学与毒理学杂志 年份:2015
OBJECTIVE To investigate the effect of P2X7receptor(P2X7r)inhibition,using a specific inhibitor(A438079)to prevent the development of liver fibrosis on human he...
Exogenous pancreatic kininogenase protects against renal fibrosis in rat model of unilateral uretera
[期刊论文] 作者:Ji-zhe Jin,Hui-ying Li,Jian Jin,Shang-guo Piao,Xiong-hu Shen,Yan-ling Wu,Jia-chong Xu,Long-ye Zhang,Yu-ji,
来源:中国药理学报(英文版) 年份:2020
Tissue kallikrein has protective function against various types of injury.In this study,we investigated whether exogenous pancreatic kininogenase (PK) conferred...
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