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Effect of antofloxacin, a novel fluoroquinolone, on pharmacokinetics of theophylline in humans:possi
[会议论文] 作者:Liu Li,Pan Xian,Liu Xiao-Dong,Xie L,Wang Guang-Ji,
来源:第二届“定量药理与新药评价”国际学术会议 年份:2010
AIM: This study evaluated the pharmacokinetic interaction between theophylline and antofloxacin in vivo and in vitro.METHODS: A randomized, 5-day treatment and 3-way crossover design was documented in...
Genistein enhances amyloid-β 42 clearance across blood-brain barrier by inducing P-glycoprotein in v
[会议论文] 作者:NIU Fang,ZHOU Fang,WU Xiao-lan,ZHANG Jing-wei,WANG Guang-ji,
来源:第十届全国药物和化学异物代谢学术会议暨第三届国际ISSX/CSSX联合学术会议 年份:2012
Objective Genistein is a good candidate as an alternative to estrogen replacement therapy for Aizheimer disease (AD)because of the effects in ameliorating learning or memory deficits of AD without inc...
Genistein Enhances Amyloid-β 42 Clearance across Blood-Brain Barrier by Inducing P-Glycoprotein in v
[会议论文] 作者:NIU Fang,ZHOU Fang,WU Xiao-lan,ZHANG Jing-wei,WANG Guang-ji,
来源:江苏省药理学会青年工作委员会成立大会暨药理学科青年科技创新学术研讨会 年份:2013
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Synergetic effect of 20(S)-ginsenoside Rh2 on ciprofloxacin: investigation on the function of efflux
[会议论文] 作者:SUN Yuan,ZHOU Fang,ZHA Wei-bin,ZHANG Jing-wei,WANG Guang-ji,
来源:第十届全国药物和化学异物代谢学术会议暨第三届国际ISSX/CSSX联合学术会议 年份:2012
Objective Bacterial drag resistance caused by effiux pump remains problematic.Our previous study showed that 20 (S)-ginsenoside Rh2 (20 (S)-Rh2) reversed multidrug resistance (MDR) in MCF-7 cells by i...
Induction of retinoid metabolism related cytochrome P450 by Chrysanthemum morifolium Ramat extract i
[会议论文] 作者:Wang Ping,Pan Xian,Liu Xiao-dong,Xie Lin,Wang Guang-ji,Guo Hao,
来源:第二届“定量药理与新药评价”国际学术会议 年份:2010
Chrysanthemum, a traditional Chinese medicine, shows various pharmacological activities including anti-inflammatory, anti-oxidative and free radical scavenging.It has long been extensively used for re...
Development and validation of an improved LC-MS/MS method for simultaneous quantitation of metformin
[会议论文] 作者:ZHANG Xue-yuan,PENG Ying,SUN Jian-guo,WAN Ping,YIN Li-fang,WANG Guang-ji,
来源:第十届全国药物和化学异物代谢学术会议暨第三届国际ISSX/CSSX联合学术会议 年份:2012
Objective To support the pharmacokinetic study of metformin (MET) hydroehloride/pioglitazone (PIO) hydroehloride tablet, an LC-MS/MS method was developed for the simultaneous determination of MET and...
The Pharmacokinetic-Pharmacodynamic Model of Azithromycin for Lipopolysaccharide-Induced Depressive-
[会议论文] 作者:HAO Kun,QI Qu,HAO Hai-Ping,WANG Guang-Ji,CHEN Yuan-Cheng,LIANG Yan,XIE Lin,
来源:第十届全国药物和化学异物代谢学术会议暨第三届国际ISSX/CSSX联合学术会议 年份:2012
A mechanism-based model was developed to describe the time course of lipopolysaccharide-induced depressive-like behavior and azithromycin pharmacodynarnics in mice.The lipopolysacchatide-induced disea...
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