Nitazoxanide相关论文
Nitazoxanide, the first thiazolide, was originally developed for the treatment of Cryptosporidium parvum. More recently,......
The pathogenesis of Alzheimer’s disease (AD) is characterized by both accumulation of β-amyloid (Aβ) plaque and forma......
Discovery of nitazoxanide-based derivatives as autophagy activators for the treatment of Alzheimer’s
Drug repurposing is an efficient strategy for new drug discovery.Our latest study found that nitazoxanide (NTZ),an appro......
Validated stability indicating methods for determination of nitazoxanide in presence of its degradat
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
选择试验犬8只,将其随机分为4个小组,每组2只。连续6 d对8只试验犬分别进行粪检,确定无贾第虫感染后,用体外纯培养的犬贾第虫滋养......
Validated stability indicating methods for determination of nitazoxanide in presence of its degradat
Three sensitive,selective and reproducible stability-indicating methods are presented for determination of nitazoxanide ......
目的:建立项空气相色谱测定药物硝唑尼特中残留溶剂的方法。方法:采用DM-WAX毛细管色谱柱(30 m×0.25 mm,0.5μm);枉温采取程序升......
The present study reports voltammetric reduction of nitazoxanide in Britton-Robinson(B-R)buffer by cyclic and square-wav......
研究一种新的硝唑尼特的合成方法。以邻乙酰水杨酸和2-氨基-5-硝基噻唑为原料,通过共沸带水的方法使原料发生酰胺化反应,仅通过一......
【目的】制备硝唑尼特纳米乳,并对其理化性质及安全性进行评价。【方法】以纳米乳的载药量、稳定性和毒性为考察指标,筛选合适的油相......
硝唑尼特经狗口服后在体内迅速代谢成替唑尼特,随后替唑尼特进一步与葡萄糖醛酸结合生成了葡萄糖醛酸替唑尼特结合物。本实验主要运......
用激光法测定了不同温度下硝唑尼特在N,N-二甲基甲酰胺(DMF)、二甲基亚砜(DMSO)、甲醇和丙酮4种溶剂体系中的溶解度与超溶解度,得到硝......
利用气相色谱-选择离子监测质谱联用仪(GC-SIM-MS)测定硝唑尼特样品中溶剂残留甲醇的含量,顶空进样,温度为70℃,时间为20 min.SIM定......
研究硝唑尼特抗隐孢子虫的活性,采用地塞米松抑制昆明鼠免疫功能,经口接种感染微小隐孢子虫孢子化卵囊,成功制备出微小隐孢子虫感染的......
为观察硝唑尼特在不同浓度、不同作用时间对离体杜氏利什曼原虫的药效作用,以6个不同浓度(6.25、12.5、25、50、100、200μg/mL)的硝......
通过对斑马鱼和赤子爱胜蚓的急性毒性试验,研究了硝唑尼特的生态毒性。结果表明,硝唑尼特在静水条件下对斑马鱼24 h LC50为2.312 m......
建立了检测狗血浆中硝唑尼特主要代谢物替唑尼特浓度的高效液相色谱法,并用于药代动力学研究。该法采用Scienhome Kromasil C18色谱......
选择试验犬8只,将其随机分为4个小组,每组2只。连续6d对8只试验犬分别进行粪检,确定无贾第虫感染后,用体外纯培养的犬贾第虫滋养体接种......
Introducing nitazoxanide as a promising alternative treatment for symptomatic to metronidazole-resis
Objective:To identify the frequencies(F) of ferredoxin and nitroreductase mutations were identified on Iranian clinical ......
目的观察硝唑尼特联合利巴韦林治疗有干扰素禁忌证的慢性丙型肝炎的疗效和安全性。方法在患者知情同意的情况下,将40例患者随机分......
Diarrhea is a common complication in solid organ transplant(SOT)recipients and may be attributed to immunosuppressive dr......
<正> 腹泻是肠道原虫感染的典型症状,以贾第鞭毛虫和溶组织内阿米巴最常见。nita-zoxanide是一种广谱抗微生物制剂,本研究以随机、......
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观察硝唑尼特、贝尼尔、咪唑苯脲、Trypan等4种药物在不同浓度、不同作用时间对路氏锥虫的体外杀灭效果。将这4种药物分别以5、10......
目的:反相高效液相色谱法测定硝唑尼特的含量及其有关物质。方法:C18色谱柱(4.6mm×150mm,填料:Hypersil,粒度:5μm),以乙腈-10mmd......
Nitazoxanide是国外上市的一种高效、广谱的治疗人、畜寄生虫和细菌感染的新药 ,目前国内尚无该产品上市。该文对其理化性质、药代......
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Nitazoxanide(NTZ)是一种具有广阔应用前景的高效、广谱抗动物与人体寄生虫、细菌和真菌感染药物,在我国还没有该产品上市,为充分发......