Radioimmunotherapy相关论文
Primary gastric non-Hodgkins lymphomas are the most common extranodal lymphomas with two histological types,diffuse larg......
1-chTNT injection by bronchofibroscopy to relieve tracheal obstruction in a patient with advanced no
Objective: To report injection of the mouse/human chimera monoclonal antibody radi(o)labelled with iodine131 (131I-chTNT......
Fractionated radioimmunotherapy using low doses of iodine-131 labeled anti-CEA monoclonal antibody a
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Avidin-biotin system pretargeting radioimmunoimaging and radioimmunotherapy and its application in m
AIM: To evaluate the multi-step pretargeting radioimmunoimaging (RII) and radioimmunotherapy (RIT) in nude mice bearing ......
AIM: To evaluate the influence of avidin chase on the side effects of radioimmunotherapy (RIT) in nude mice bearing huma......
目的 观察131I-肿瘤细胞核人鼠嵌合单克隆抗体(131I-chTNT)放射免疫治疗中晚期肺癌的疗效.方法 15例确诊的中晚期肺癌患者,通过静......
前列腺特异性膜抗原(PSMA)是一种跨膜糖蛋白,几乎表达于所有前列腺癌,在转移性激素抵抗性前列腺癌中表达量显著增加。放射免疫治疗(R......
放射免疫治疗是将单克隆抗体(单抗)耦联放射性核素,在肿瘤局部产生足够的电离辐射生物学效应,达到高效、低毒的治疗效果.非霍奇金......
188Re labeled monoclonal antibodies are potential candidates for use in radioimmunotherapy. S-Bz-MAG3 as a bifunctional ......
目的探讨131I标记的抗CD80单克隆抗体4E5(131I-4E5)对荷人淋巴瘤裸鼠的治疗效果。方法采用Iodogen法进行4E5的131I标记,并对131I-4E......
,Radioimmunotherapy of carcinoma of colon with [131I]-labeled recombinant chimeric monoclonal antibo
Aim: To study the distribution of [131I]-labeled anti-CEA MoAbs and its therapeutic effect on the human colonic cancer m......
目的 探讨利用放射性核素示踪技术研究半乳糖抗小鼠CD3单克隆抗体(Gal-Ant-CD3 McAb)作为原发性肝癌(PLC)术后免疫治疗载体的......
目的 探讨131I-Herceptin在荷人乳腺癌裸鼠模型中的生物分布及其对人表皮生长因子2(HER2)高表达乳腺癌的放射免疫治疗疗效.方法 13......
放射性核素标记的单克隆抗体能够特异地与肿瘤相关抗原结合,以该药物为基础的RIT和RII用于肿瘤治疗和诊断,是非常有效的方法。越来越......
放射免疫治疗(RIT)因具有较好的靶向性并可最大限度减少对非靶器官的放射性损伤而被用于肿瘤的辅助和(或)巩固治疗。以前实体瘤RIT......
Monoclonal antibodies (MAbs) are a relatively new innovation in cancer treatment.At present,some monoclonal antibodies h......
Inhibiting effects of 131 I-labeled anti-CEA monoclonal antibodies injected intrasplenically on live
131 I-labeled anti-CEA monoclonal antibody injected intrasplenically has better effects on inhibiting liver metastasis f......
The purpose of this study was to assess the absorbed dose of tumor and main critical organs in 131I labeled chimeric tum......
Avidin-biotin system pretargeting radioimmunoimaging and radioimmunotherapy and its application in m
AIM: To evaluate the multi-step pretargeting radioimmunoimaging (RII) and radioimmunotherapy (RIT) in nude mice bearing ......
188Re labeled monoclonal antibodies are potential candidates for use in radioimmunotherapy. S-Bz-MAG3 as a bifunctional ......
The purpose of this study was to assess the absorbed dose of tumor and main critical organs in 131I labeled chimeric tum......
CHANGES OF SERUM ALPHA FETOPROTEIN BEFORE AND AFTER RADIOIMMUNOTHERAPY IN PATIENTS WITH HEPATOCELLUL
CHANGESOFSERUMALPHAFETOPROTEINBEFOREANDAFTERRADIOIMMUNOTHERAPYINPATIENTSWITHHEPATOCELLULARCARCINOMAZengZhaochong;曾昭冲;TangZhao.........
目的:探讨核素标记抗细胞膜抗原单克隆抗体联合核素标记抗细胞核单克隆抗体瘤内注射治疗荷人大肠癌裸鼠移植瘤的可行性和优越性,为......
介绍了用于放射性核素免疫治疗的单克隆抗体90年代以来的最新研究进展.归纳了用于放免治疗的放射性核素和单克隆抗体,并比较了各自......
Avidin-biotin system pretargeting radioimmunoimaging and radioimmunotherapy and its application in m
AIM: To evaluate the multi-step pretargeting radioimmunoimaging (RII) and radioimmunotherapy (RIT) in nude mice bearing ......
目的:探讨铼-188(188Re)标记前列腺特异膜抗原单克隆抗体7E11C5.3(188Re-7E11C5.3)对前列腺癌细胞系LNCaP的体外抑制作用。方法 采用2-巯......
目的探讨131Ⅰ标记抗KDR单抗对SCID小鼠人膀胱癌皮下移植瘤模型瘤体生长的抑制作用.方法在复制SCID小鼠人膀胱癌皮下移植瘤模型的......
目的以荷人膀胱癌、胆管癌小鼠为模型,研究血管内皮生长因子(VEGF)及其受体KDR、整合素αvβ3受体在肿瘤的核素显像及治疗中的应用......
探讨99mTc-Annexin Ⅴ凋亡显像在评价淋巴瘤131I-Rituximab放射免疫治疗疗效中的价值及其最佳显像时间。荷淋巴瘤裸鼠经肿瘤间质、......
探讨131I标记组合单克隆抗体S102、T9、CL-3(Cocktail法)局部导向治疗肝癌的近期疗效、毒副反应.采用IODO-GEN法标记131I-McAb,B超......
目的探讨经肝动脉灌注^131 I-HAbl8F(ab’)2治疗肝癌合并门脉癌栓的价值。方法8例合并门脉癌栓的晚期肝癌患者行经肝动脉超选择灌注^......
目的 观察一种集化疗和内照射于一体的新型“双弹头”免疫导向治疗肝癌的效果。方法 以大鼠抗人甲胎蛋白(AFP)单克隆抗体(抗AFPMcAb)和马抗人AFP多......
目的:研究^131 I标记的Rituximab对B细胞淋巴瘤细胞的生物学效应以及对荷人Raji细胞移植瘤裸鼠的放射免疫治疗效果,为放射免疫导向治......
本文报告经^131I-抗人肝癌单克隆抗体肝动脉内治疗后,肝癌病人血中抗鼠抗体(HAMA)的检测结果。以产接酶联免疫吸附法(ELISA)检测,给药后HAMA阳性率为34.4%(11/32),阳性高峰......
目的 131I标记人源抗HBsAg Fab经腹腔注射治疗荷人肝癌裸鼠移植瘤,与131I-S102比较,评价其作为肝癌放射免疫治疗(RIT)的可能性。方......
目的探讨用“冷抗体”封闭前后^131I-Rituximab对荷人淋巴瘤裸鼠的治疗与显像效果。方法建立荷人淋巴瘤裸鼠模型,病理示B细胞非霍奇......
放射免疫治疗是放射性核素治疗的重要组成和研究的重点之一。Zevalin~(TM)第一个得到FDA批准的用于治疗复发或顽固性低度恶性非霍......
目的:研究大肠癌术前放射免疫治疗及化疗( 或导向化疗) 对大肠癌组织及细胞的影响。方法:63 例大肠腺癌患者随机分成五组。A 组16 例,术前肿......
恶性胶质瘤以手术切除为主,辅以放疗和化疗,在此基础上再进行适当的放射免疫治疗,可进一步延长生存期.131I和90Y标记的抗腱生蛋白......
放射免疫治疗(RIT)实体性、非实体性肿瘤具有独到优势,许多新的核素和抗肿瘤导向载体被用于制备肿瘤RIT药物.高能β射线发射体和α......
目的研究核素131I标记Herceptin对Her-2表达阳性乳腺癌细胞株的特异性杀伤作用.为放射免疫导向治疗奠定基础.方法应用IODO-GEN方法......
目的研究^131I标记的Rituximab对CD20表达阳性的B细胞淋巴瘤细胞的特异性杀伤作用,为放射免疫导向治疗提供实验依据。方法应用IODO-......
目的:观察131^I-CD133mAb在体内外对高表达CD133抗原的Huh-7人肝癌细胞的靶向抑制作用。方法采用氯胺T法制备并鉴定131^I-CD133mAb;......
目的探讨核素标记人源化抗(乙型肝炎)乙肝表面抗原Fab片段(抗HBsAgFab)联合核素标记抗纽胞核单克隆抗体(chTNT)瘤内注射治疗荷人肝癌移植......
作者对^131Ⅰ标记铁蛋白多克隆抗体,抗人肝癌单克隆抗体和乙型肝炎病毒X蛋白单克隆抗体的药代动力学进行研究。结果:(1)裸鼠人肝癌模型^131Ⅰ-FtAb分别......
RADIOIMMUNOTHERAPYINTREATMENTOFUNRESECTABLEHEPATOMA-AREPORTOF43CASESLiuKangda刘康达TangZhaoyou汤钊猷FanZhen范桢LuJizhen陆继珍YuYeqin余业勤Z.........
Radiotherapy(RT)is a widely used way for cancer treatment.However,the efficiency of RT may come with various challenges ......
<正>随着肿瘤免疫学和细胞生物学技术的发展,免疫治疗在淋巴瘤尤其是非霍奇金淋巴瘤的治疗中得到了越来越广泛的应用,淋巴瘤的治疗......