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Tumor growth and metastasis are angiogenesis-dependent. Anti-angiogenic therapy represents a new strategy for the devel......
Aim: To investigate the anticancer effects and the molecular mechanisms of deguelin on human U937 leukemia cells, and t......
Evaluation of miR-122-regulated suicide gene therapy for hepatocellular carcinoma in an orthotopic m
Objective:Intratumoral administration of adenoviral vector encoding herpes simplex virus(HSV)thymidine kinase(TK)gene(Ad......
Cardiotoxicity as a result of cancer treatment is a novel and serious public health issue that has a significant impact ......
Fueling the engine and releasing the break: combinational therapy of cancer vaccines and immune chec
Immune checkpoint inhibitors are increasingly drawing much attention in the therapeutic development for cancer treatment......
Microwave-assisted synthesis of some novel fluorinated pyrazolo[3,4-d]pyrimidine derivatives contain
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Design and synthesis of novel water-soluble amino acid derivatives of chlorin p6 ethers as photosens
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 探讨ATP生物荧光肿瘤体外药敏检测技术(ATP-TCA)指导恶性实体瘤患儿临床化疗的意义,为恶性肿瘤患儿的个性化治疗提供参考.方......
运用文献资料分析方法,综述了芦荟多糖的免疫调节、抗病毒、抗肿瘤、抗辐射、抗炎症等多种生物活性作用和相关研究进展.......
Microwave-assisted synthesis of some novel fluorinated pyrazolo[3,4-d]pyrimidine derivatives contain
A facile microwave-assisted procedure for synthesis of novel fluorinated pyrazolo[3,4-d]pyrimidine derivatives containin......
白本香[Aquilariasinensis(Lour.)Gilg]是我国特有的珍稀濒危药用植物。对已分离得到的白木香内生真菌的发酵液提取物的抗肿瘤抗菌活......
[目的]探讨子宫颈癌体外药物敏感性的临床意义.[方法]采用MTT法检测了20种常用化疗药物在46例子宫颈癌组织中的药物敏感性,计算其......
在无水乙醇介质中,合成了4种新型稀土三元固体配合物.通过红外光谱、紫外光谱、元素分析和TG-DTA等技术手段测试,确定了配合物的化......
采用微波辐射、硅胶负载和催化合成辣椒素类似物Aranvil,在高产率地得到Aranvil的同时,建立了一种微波辅助、硅胶负载和催化合成辣......
聚合物纳米粒子作为抗肿瘤药物载体具有优良的性能和广阔的应用前景,主要表现在其能增溶疏水性抗癌药物,增加抗癌基因药物与蛋白类药......
在探索新的抗肿瘤药物过程中,作者设计并合成了十三个具有3,5-二酮哌嗪片段及对位二乙酰氧基苯结构的化合物(Ⅲ)。经对肿瘤细胞P<sub......
[目的]为开发利用冬凌草根际土壤微生物资源。[方法]使用K562细胞的SRB法筛选模型,对从贵州省施秉县采集的冬凌草根际土壤样品中分......
Pharmacological Study on Antitumor Activity of 5-Fluorouracil-1-Acetic Acid and Its Rare Earth Compl
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为探讨夜香树(CN)不同提取物体对体外培养的肿瘤细胞的作用,采用系统溶剂法提取CN皂苷和多糖,采用MTT法、细胞集落形成法、生长曲......
肿瘤是一种血管生成依赖性疾病,肿瘤的生成、转移均与血管生成密切相关。烟曲霉素合成类似物TNP-470能有效抑制肿瘤血管生成,破坏血......
目的:研究槲皮素抗小鼠P388白血病的作用。方法:采用DBA/2小鼠腹腔注射P388细胞的方法建立白血病小鼠模型,80只小鼠随机分为空白对照组......
提取4种细菌胞外多糖,研究其协同抗肿瘤作用.结果发现,4种多糖复合组的瘤重均明显低于各种多糖单独组,各种多糖间的免疫增强和抗瘤......
目的体外实验明确大蒜油能否增强肝枯否细胞(kupffer cell,KC)的抗肿瘤活性。方法采用酶消化法提取小鼠肝脏枯否细胞,分别以含大蒜......
以水飞蓟宾和氨基酸为原料,通过常规方法合成了一系列具有靶向性的水飞蓟宾-氨基酸席夫碱,并对其抗肿瘤作用进行研究.采用核磁共振......
通过紫外-可见光谱、荧光光谱和红外光谱等方法研究了药物10-羟基喜树碱(HCPT)的光谱性质.采用溴化噻唑蓝四氮唑(MTT)法测定了HCPT对3......
合成5-氟尿嘧类衍生物。方法用三氯锗基丙酰氯与2,4-二(三甲基硅氧基)-5-氟尿嘧啶反应得到1-(三氯锗基丙酰基)-5-氟尿嘧啶(Ⅰ),(Ⅰ)经水解即得到基水解产物......
目的:了解没食子酰表没食子儿茶素(EGCG)抗肿瘤作用。方法:用小鼠肉瘤180(S-180)、小鼠肝癌(Hep)为瘤株,对EGCG进行体内外抗肿瘤药效试验和观察春对荷瘤小鼠免疫......
Two nicotinamides have been synthesized by coupling aromatic amines with equimolar quantities of substituted nicotinic a......
The Reaction of Cyanoacetylhdrazine with Furan-2-Aldehyde: Novel Synthesis of Thiophene, Azole, Azin
The reaction of cyanoacetylhydrazine 1 with furan-2-aldehyde 2 gives the hydrazide-hydrazone derivative 3. The latter co......