geneediting相关论文
A FLASH pipeline for arrayed CRISPR library construction and the gene function discovery of rice rec
Clustered regularly interspaced short palindromic repeats(CRISPR)-CRISPR-associated protein 9(Cas9)-mediated gene editin......
先天性肺疾病病因复杂,大多由单基因突变引起,目前临床治疗方法有限,病死率高。基因编辑技术的发展及广泛应用为呼吸系统单基因病的治......
CRISPR/Cas9 gene editing and natural variation analysis demonstrate the potential for HvARE1 in impr
Nitrogen is a major determinant of grain yield and quality. As excessive use of nitrogen fertilizer leads to environment......
Rice is one of the most important food crops in the world. Weeds seriously affect the rice yield and grain quality. In r......
Manipulation of flowering time to develop cultivars with desired maturity dates is fundamental in plant breeding. It is ......
The 2020 Nobel Prize in Chemistry recognized CRISPR-Cas9,a super-selective and precise gene editing tool.CRISPR-Cas9 has......
[目的]二化螟Chilo suppressalis是中国和其他亚洲地区为害水稻的重要害虫.由于缺乏遗传学操作工具,对二化螟的功能基因组学研究受......
Generation of mutants with clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein ......
Highly efficient, genotype-independent transformation and gene editing in watermelon (Citrullus lana
Efficient genetic transformation has the potential to advance research and breeding in watermelon (Cit-rullus lanatus), ......
Biotechnological interventions for the sustainable management of a global pest,whitefly (Bemisia tab
Whiteflies (Bemisia tabaci) are polyphagous invasive hemipteran insects that cause serious losses of important crops by ......
Transcription activator:like effector nucleases (TALENs) are powerful novel research tools that enable targeted gene dis......
Oligonucleotide-based targeted gene mutagenesis in transgenic Eimeria tenella EtM2e line via CRISPR/
Eimeria parasites as importantly obligate intracellular apicomplexan protists can cause coccidiosis,resulting in high ec......
Generation and characterization of a novel CYP3A1/2 double knockout rat model using CRISPR-Cas9 syst
OBJECTIVE Cytochrome P450 (CYP) 3A accounts for nearly 30% of total CYP enzymes in human liver and participates in the m......
Cytosolic delivery of CRISPR/Cas9 ribonucleoproteins for genome editing using chitosan-coated red fl
Though plenty of viral and non-viral methods have been rapidly developed for the delivery of the CRISPR/Cas9 system,the ......
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Butterflies are exceptionally diverse but their potential as an experimental system has been limited by the difficul......
Human Induced pluripotent stem cells (iPSCs) have pluripotency and self-renewal in common with embryonic stem cells ......
Rice blast and bacterial blight are important diseases of rice (Oryza sativa) caused by the fungus Magnaporthe oryzae an......
人诱导多潜能干细胞(hiPSC)可定向分化为眼特定细胞组织,在视网膜细胞移植、角膜移植、晶状体再生等领域有应用前景;成簇规律间隔短回......
Gene editing, as a breakthrough in life science and medicine, makes significant scientific im-pact. The entire developme......
Gene therapy has become the most effective treatment for monogenic diseases.Congenital LEPTIN deficiency is a rare autos......
【摘 要】 猪内源性逆转录病毒(porcine endogenous retrovirus,PERV)是一种以前病毒DNA形式整合入猪基因组中的逆转录病毒,它可随细胞......
Chain-shattering Pt(Ⅳ)-backboned polymeric nanoplatform for efficient CRISPR/Cas9 gene editing to en
CRISPR/Cas9 system has become a promising gene editing tool for cancer treatment.However,development of a simple and eff......
Generation of nonhuman primate retinitis pigmentosa model by in situ knockout of RHO in rhesus macaq
Retinitis pigmentosa (RP) is a form of inherited retinal degenerative diseases that ultimately involves the macula,which......