homoharringtonine相关论文
Homoharringtonine (HHT) was studied in our Institute for many years.In collaboration with other institutions it was prov......
To study the anti-HBV activity of homoharringtonine、 IFN-a 1b 、 hydroxycamptothecin and norfloxacin invitro.The four d......
Homoharringtonine in combination with cytarabine and aclarubicin as induction therapy improves remis
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Cephalotaxine (CET) is the parent member of a group of Cephalotaxus alkaloids1 and its absolute configuration (3S,4S......
高三尖杉酯碱(HHT)是具有抗肿瘤活性的生物碱,对急性粒细胞白血病(AML)有较好的疗效,且其不良反应较其他抗恶性肿瘤药物低.信号转......
目的:观察小剂量HA方案治疗初诊成人高白细胞性急性髓系白血病(HAML)1个疗程后的疗效及不良反应.方法:23例初诊成人HAML患者,予以......
本文旨在系统评价高三尖杉酯碱巩固治疗慢性粒细胞白血病的疗效和安全性.通过计算机检索PubMed、The Cochrane Library、EMbase、V......
AIM: To identify genes responsive to apoptosis in HL-60 cells treated by homoharringtonine. METHODS: cDNA microarray tec......
Aim: To classify the genes responsible for apoptosis in QGY-7703 cells in-duced by homoharringtonine (HHT).Methods: Apop......
Collaboration of c-KIT mutations with AML1-ETO (AE) has been demonstrated to induce t(8;21) acute myeloid leukemia (AML)......
Homoharringtonine (HHT),a plant alkaloid from Cephalotaxus harringtonia,exhibits a unique anticancer mechanism and has b......
Gene chip technology was used to determine the gene expression profiles in apoptotic K562 cells induced by homoharringto......
Effect of Homoharringtonine on Corneal Haze after Excimer Laser Photorefractive Keratectomy in Rabbi
To evaluate the inhibiting effect of Homoharringtonine HHT) on the ceal haze after excimer laser photorefractive keratec......
Correlation between survivin mRNA expression and homoharringtonine induced apoptosis of malignant he
Background The inhibitor of apoptosis (IAP) gene family is involved in the suppression of apoptotic cell death as well a......
Objective: To observe the long-term effect of homoharringtonine (HHT) on chronic granulocytic leukemia (CGL) and its pha......
Background Homoharringtonine (HHT) is a cephalotaxine ester derived from an evergreen tree found wildely throughout sout......
Correlation between survivin mRNA expression and homoharringtonine induced apoptosis of malignant he
Background The inhibitor of apoptosis (IAP) gene family is involved in the suppression of apoptotic cell death as well a......
Objective: To explore the effect of homoharringtonine (HHT) on bone morrow CD34+CD7+ cells in chronic granulocytic leuke......
Effect of Homoharringtonine on Corneal Haze after Excimer Laser Photorefractive Keratectomy in Rabbi
To evaluate the inhibiting effect of Homoharringtonine HHT) on the corneal haze after excimer laser photorefractive kera......
目的探讨高三尖杉酯碱(homoharringtonine,HHT)对肝癌细胞PLC5增殖的影响及其可能的机制。方法采用CCK-8以及EdU检测HHT对PLC5细胞......
目的:研究干扰素-α(IFN-α)联合高三尖杉酯碱(HHT)对K562细胞端粒酶逆转录酶及端粒酶的作用,并探讨其与细胞凋亡的关系。方法:IFN-α、HH......
目的:探讨抑制白血病K562细胞叉头框蛋白M1(Fox M1)是否增强细胞对高三尖杉酯碱(HHT)的敏感性。方法:HHT以不同浓度(0、0.015、0.030和0.0......
目的 探讨局部注射高三尖杉酯碱减少翼状胬肉术后复发的效果。方法 63例翼状胬肉患者随机分为3组:A组29例29眼,术前局部注射高三尖杉酯碱;B组......
目的研究化疗药物诱导HL60-n白血病细胞核因子-κB(NF-κB)活化与凋亡的关系,并探讨地塞米松(DXM)对其的影响.方法采用电泳迁移率......
目的 评估高三类杉酯碱(homoharringtonine,HH)作为青光眼滤过手术辅助药的中远期疗效和并发症。方法 采用前瞻性随机对照方法将63例......
目的:研究药物高三尖杉酯碱是否对人乳腺癌MDA—MB-453细胞具有生长抑制和诱导凋亡作用,以挖掘研发治疗乳腺癌的新药物。方法:常规培......
目的:观察伊马替尼联合高三尖杉酯碱(HHT)治疗初诊慢性髓细胞性白血病(CML)的疗效和毒副反应。方法:33例CML患者随机分为2组,伊马替尼联......
目的:研究高三尖杉酯碱(HHT)对人胃癌SGC-7901细胞诱导凋亡的作用,并探讨其可能机制。方法:常规培养人胃癌SGC-7901细胞,根据HHT浓度分......
Objective: To observe the long-term effect of homoharringtonine (HHT) on chronic granulocytic leukemia (CGL) and its pha......
目的将在长期的 granulocytic 白血病(CGL ) 在骨头次日 CD34+CD7+ 房间上探索 homoharringtonine (HHT ) 的效果。骨头次日 CD34+......
目的 建立测定兔眼球组织中高三尖杉酯碱(HHT)的含量及其分布。方法 以三尖杉酯碱(HT)为内标,荧光法检测;眼球旁注射HHT,分离各眼球组织......
目的:研究高三尖杉酯碱(Homohrringtonine,HHT)对HL60细胞端粒酶活性的影响.方法:不同浓度HHT作用于HL60细胞12 h及0.02 mg/L HHT......
目的:探索伊马替尼(IM)、尼罗替尼(NL)这两种药物分别与高三尖杉酯碱(HHT)联合应用对慢性粒细胞白血病(CML)细胞系K562增殖、凋亡以及BCR-AB......
采用动物肝微粒体体外代谢法对高三尖杉酯碱进行了代谢转化的研究。应用梯度洗脱—反相HPLC结合二极管陈列检测器对体外代谢体系进......
用细胞培养法和癌细胞浸袭实验,观察几种植物来源不同作用机理的抗癌药如紫杉醇、三尖杉酯碱、高三尖杉酯碱及喜树碱,对黑色素瘤高转......
目的 探讨亚砷酸+全反式维甲酸联合高三尖杉酯碱(homoharringtonine,HHT)治疗急性早幼粒细胞白血病(acute promyelocytic leukemia,APL......
[目的]为充分发掘篦子三尖杉(Cephalotaxus oliveriMast)内生真菌的应用价值。[方法]采用HPLC对内生真菌菌株gyzy-20的发酵提取组分......
探讨高三尖杉酯碱、干扰素α1b、羟基喜树碱和诺氟沙星这四种药物对乙肝病毒的体外抑制作用。利用HBV全基因组转染的人肝癌细胞系(H......
目的:研究高三尖杉酯碱(HHT)、干扰素α-2b(IFNα-2b)和两者联合(HHT+IFNα-2b)对白血病源性树突状细胞(DCs)的促成熟作用。方法:在白血病多药......
本实验显示高三尖彬碱能在〉5μg/ml浓度以上抑制兔红细胞膜上钙调蛋白活性,推测高三尖杉酯碱能通过影响癌细胞钙调蛋白活性干扰细胞代谢......
目的观察高三尖杉酯碱抑制兔眼内纤维增生的效果.方法建立20只青紫蓝兔右眼细菌性眼内炎模型,随机分为实验组和对照组,每组各10只.......
目的了解球旁注射高三尖杉酯碱对实验性增生性玻璃体视网膜病变(PVR)的防治效果.方法兔眼球扁平部切开8mm,玻璃体腔内注射自体全血......
目的 探讨伊马替尼联合高三尖杉酯碱治疗慢性粒细胞性白血病(chronic myelocytic leukemia,CML)的疗效。方法 选取80例CML患者,年龄4......
目的:研究低分子RNA与抗白血病药物高三尖杉酯碱联用对HL-60细胞药物敏感性的影响。方法:采用细胞形态学观察、四唑盐(MTT)比色法分析......
目的:观察高三尖杉酯碱(HHT)、吡喃阿霉素(THP)、阿糖胞苷(Ara-C)三药联合(HTA)方案治疗初诊急性髓系白血病(AML)的疗效与安全性。方法:回顾性......
目的探讨沙利度胺综合治疗骨髓增生异常综合征(MDS)的疗效.方法根据FAB分型将46例MDS患者分为低危组和高危组,低危组24例包括难治......
直肌延长术矫正斜视林意玲,王映芬(广东医学院附属医院眼科,湛江524001)矫正共同性斜视,以往一直采用肌肉徒后及拮抗肌缩短术。Nolan(1983)改良了直肌延长......
目的:了解术前局部注射高三尖极酯碱联合地塞米松对减少翼状胬肉术后复发的效果。方法:将72例翼状胬肉患者分为两组,治疗组42例42眼,术前7、3及......
采用MTT法检测高三尖杉酯碱对HepG2细胞体外培养的抑制作用.将常规用96孔板培养的HepG2细胞作为空白组,其余分11个剂量的给药组,相......