smallmolecules相关论文
Unfolded protein response(UPR)is a stress response that is specific to the endoplasmic re-ticulum(ER).UPR is activated u......
Immunotherapy plays a compelling role in cancer treatment and has already made remarkable progress.However,many patients......
Modifying the chemical structures of porphyrin small molecules for bulk heterojunction organic solar
Two porphyrin small molecules substituted with either a furan-or a selenophenelinked diketopyrrolopyrrole unit have been......
Small-Molecule-Induced Transcription Repression through Interfering with NM23-H2 Binding to G-quadru
NM23-H2 protein is identified as a transcriptional factor of the important oncogene c-myc,that can bind specifically to ......
Discovery of Novel Allosteric Effectors Based on the Predicted Allosteric Sites for D-3-Phosphoglyce
D-3-phosphoglycerate dehydrogenase (PGDH) from Escherichia coli catalyzes the first critical step in serine biosynthesis......
The disruption of protein-protein interactions with co-chaperones and client substrates as a strateg
The 90-kiloDalton (kD) heat shock protein (Hsp90) is a ubiquitous,ATP-dependent molec-ular chaperone whose primary funct......
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MicroRNAs are endogenous small, non-coding RNAs that regulate gene expression at post-transcriptional level.It is estima......
Bioactive small molecules that specifically target protein-protein and protein-substrate interactions often represent es......
Discovery of novel allosteric effectors based on the predicted allosteric sites for D-3-phosphoglyce
D-3-phosphoglycerate dehydrogenase (PGDH) from Escherichia coli catalyzes the first critical step in serine biosynth......
c-MYC is a classical G-quadruplex-relating gene that is considered as an effective target for anticancer therapy [1]......
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Direct conversion of human fibroblasts into dopaminergic neuron-like cells using small molecules and
Background:Generation of neurons is essential in cell replacement therapy for neurodegenerative disorders like Parkinson......
Recent progress in organic hole-transporting materials with 4-anisylamino-based end caps for efficie
Perovskite solar cells(PVSCs)have emerged as a promising photovoltaic technology and have attracted wide research intere......
Enormous studies have corroborated that long non-coding RNAs(lncRNAs)extensively participate in crucial physiological pr......
