ISCHEMIAREPERFUSION相关论文
Exogenous glutathione exerts a therapeutic effect in ischemic stroke rats by interacting with intras
We previously showed that oral administration of exogenous glutathione(GSH)exerted a direct and/or indirect therapeutic ......
Background : Anoxic brain injuries represent the main determinant of poor outcome after cardiac arrest (CA). Large anima......
Do pyroptosis, apoptosis, and necroptosis (PANoptosis) exist in cerebral ischemia? Evidence from cel
Some scholars have recently developed the concept of PANoptosis in the study of infectious diseases where pyroptosis, ap......
Dingxin Recipe(定心方) Prevents Ischemia/Reperfusion-Induced Arrhythmias via Up-regulating Prohibitin a
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Neuroprotective Autophagic Flux Induced by Hyperbaric Oxygen Preconditioning is Mediated by Cystatin
We have previously reported that Cystatin C (CysC) is a pivotal mediator in the neuroprotection induced by hyperbaric ox......
Comparison of quercetin and resveratrol in the prevention of injury due to testicular torsion/detors
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Dual protective role of HO-1 in transplanted liver grafts: A review of experimental and clinical stu
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ThePI3K/Akt,p38MAPKandJAK2/STAT3SignalingPathwaysMediatestheProtectionofSO2AgainstAcute
Aim: ThepresentstudyaimtoverifiedtheroleofSO2onlimbI/RinducedALI,andinvestigatewhetherPI3K/Akt,p38MAPKand JAK2/STAT3Path......
The PI3K/Akt, p38MAPK and JAK2/STAT3 Signaling Pathways Mediates the Protection of SO2 Against Acute
Aim: Sulfur dioxide(S02)is naturally synthesized by glutamate-oxaloacetate transaminase(GOT)from L-cysteine in mammalian......
Aim: The purpose of this study was to determine the effects of SCU on vascular endothelium dependent relaxation injury i......
IL-25 elicits innate lymphoid cells and multipotent progenitor type 2 cells that reduce renal ischae
IL-25 is an important immune regulator that can promote Th2 immune response-dependent immunity, inflammation,and tissue ......
Neuroprotection of total flavones of rhododendra in cerebral ischemia/reperfusion and in neuronal cu
Aim: Total flavones of rhododendra (TFR) is a powerful antioxidant which is isolated from the traditional Chinese herb r......
Renal-targeting triptolide-glucosamine conjugate exhibits lower toxicity and superior efficacy in at
We previously reported a novel triptolide(TP)-glucosamine conjugate(TPG)that specifically accumulated in kidneys and pro......
Cardioprotection of H2S against ischemia reperfusion injury through inhibiting endoplasmic reticulum
To investigate whether hydrogen sulfide (H2S) protect the heart against myocardial ischemia/reperfusion (I/R) injury by ......
Background: Ischemia/reperfusion injury (IRI) of the intestine is associated with a high morbidity and mortality in surg......
Chronic intermittent hypobaric hypoxia ameliorates ischemia/reperfusion injury of heart via a Na+/Ca
Aim:This study was to investigate the calcium homeostasis mechanism,especiallly the role of Na+/Ca2+ exchanger in cardia......
Schisandrin B prevents hind limb from ischemia-reperfusion-induced oxidative stress and inflammation
Schisandrin B (ScB),isolated from Schisandra chinensisand (S.chinensis) has been used commonly in traditional Chinese me......
The potential role of microRNA-1 (miR-1) in ischemia/reperfusion (I/R)-induced injury is not well illustrated.The presen......
Cardioprotective Effects of Gypenoside XVII on Endoplasmic Reticulum Stress-Mitochondrial Damage Cro
Aim: Effective strategies have been developed to prevent or improve recovery from myocardial ischemia and reperfusion(I/......
The healing property of reperfusion therapy that one of the treatments for myocardial infarction(MI)is limited by the da......
Exogenous hydrogen sulfide postconditioning protects isolated rat hearts from ischemia/reperfusion i
Sirt1 is a highly conserved nicotinamide adenine dinucleotide(NAD+)dependent histone deacetylase which plays an importan......
Dingxin Recipe(定心方) Prevents Ischemia/Reperfusion-Induced Arrhythmias via Up-regulating Prohibitin a
Objective: To identify the underlying mechanisms of the protective effects of Dingxin Recipe(定心方, DXR), a Chinese com......
Melatonin prevents cell death and mitochondrial dysfunction via a SIRT1-dependent mechanism during i
Silent information regulator 1 (SIRT1), a type of histone deacetylase, is a highly effective therapeutic target for prot......
Dynamic changes of CD4+CD25high regulatory T cells close related to renal function recovery in the e
Background Ischemia-reperfusion injury (IRI) is critical in the pathogenesis of acute failure and graft rejection.Regula......
Therapeutic Time Window and Underlying Therapeutic Mechanism of Breviscapinun Injection Against Cere
Aim of this study: Our study was designed to investigate the therapeutic time window and underlying therapeutic mechanis......
Therapeutic Time Window and Underlying Therapeutic Mechanism of Breviscapinun Injection against Cere
Our study was designed to investigate the therapeutic time window and underlying therapeutic mechanism of breviscapinun ......
Effects of total flavonoids of Rhododendra simsii on ameliorating brain injury via G protein-coupled
OBJECTIVE To explore the effect of total flavonoids of Rhododendra simsii(TFR)on improving cerebral ischemia/reperfusion......
The morbidity and mortality of cardiovascular diseases are very high,which has attracted more and more attention all ove......
Study on potential mechanism of hyperoside on improving ischemia/reperfusion injury based on network
OBJECTIVE To predict the potential targets of hyperoside(Hyp)on improving ischemia/reperfusion injury by network pharmac......
A soluble receptor for advanced glycation end-products inhibits myocardial apoptosis induced by isch
sRAGE can protect cardiomyocytes from apoptosis induced by ischemia/reperfusion (I/R).However, the signaling mechani......
硫化氢可以在哺乳动物循环系统内源性产生.硫化氢能减轻心肌缺血/再灌注损伤,这一保护作用的机制包括:清除自由基、抑制炎症反应、......
Expression profile of circular RNAs in myocardial ischemia/reperfusion with and without intermittent
Dear Editor,Myocardial injury following ischemia/reperfusion(I/R)is a common clinical scenario in patients suffering fro......
目的:探讨运动预处理对局灶性脑缺血再灌注诱导的大鼠脑梗死的影响及其可能机制.方法:将60只雄性SD大鼠随机分为缺血再灌注组(IR组......
目的探讨经鼻腔给予促红细胞生成素(erythropoietin，EPO)对急性脑缺血再灌注大鼠的神经功能及脑组织CD31表达的影响。方法100只SD大......
Neuroprotective effect of melatonin against ischemia/reperfusion-induced neuronal apoptosis in mouse
BACKGROUND: Some experiments have demonstrated that melatonin (N-aceyl-5-methoxytryptamine, Mel) has antioxidation. Howe......
Changes in corticocerebral morphology in a rat model of focal cerebral ischemia/reperfusion injury f
BACKGROUND: Cerebral ischemia/reperfusion injury has been shown to induce inflammatory reactions,including white blood c......
Cervical sympathetic trunk transection affects inducible nitric oxide synthase expression in rat hip
BACKGROUND: The stellate ganglion block (SGB) plays a protective role in focal cerebral ischemia/reperfusion injury. The......
Effects of transection of cervical sympathetic trunk on cerebral infarct volume and oxygen free radi
BACKGROUND: Stellate ganglion block (SGB) plays a protective role on the brain, but the precise mechanism of action is n......
Effects of strain, body mass, and thread tip preparation on the establishment of focal cerebral isch
BACKGROUND: What are the successful factors of the establishment of the thread-blocking method for focal cerebral ischem......
Neuroprotection of phenolic alkaloids from Menispermum dauricum versus melatonin against oxygen-gluc
BACKGROUND: Recent studies have demonstrated that phenolic alkaloids from Menispermum dauricum (PAMD) can protect the he......
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Differential protein expression in spinal cord tissue of a rabbit model of spinal cord ischemia/repe
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Ketamine inhibits c-Jun protein expression in mouse hippocampus following cerebral ischemia/reperfus
A model of cerebral ischemia and reperfusion was established in mice. Mice were treated with ketamine via intraperitonea......
As a neuroprotective drug for the treatment of ischemic stroke, 3-n-butylphthalide, a celery seed ex-tract, has been app......
Electroacupuncture improves neurovascular unit reconstruction by promoting collateral circulation an
Acupuncture at Shuigou (GV26) shows good clinical efficacy for treating stroke, but its mechanism remains poorly underst......
2-(2-Benzofuranyl)-2-imidazoline treatment within 5 hours after cerebral ischemia/reperfusion protec
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目的 观察活血益智片对脑血管性痴呆(VD)大鼠脑组织N-甲基D-天冬氨酸受体(NMDAR)表达及一氧化氮(NO)5-羟色胺(5-HT)含量影响.方法 ......
Effect of hydro-alcoholic extract of Olea europaea on apoptosis-related genes and oxidative stress i
Objective: To evaluate the impact of Olea (O.) europaea extract on markers of oxidative stress and apoptosis of ovarian ......
Effects of Buyang Huanwu Decoction on Apoptosis of Nervous Cells and Expressions of Bcl-2 and Bax in
Objective: To study the effect of Buyang Huanwu Decoction (补阳还五汤BYHWD) on spinal ischemia-reperfusion injury and ex......
