Parkinson’s相关论文
Virtual Cognitive Screenings and Interviews of Patients with Neurodegenerative Conditions Associated
The current pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), commonly referred to as COVID-19, ......
BACKGROUND Visual hallucination(VH)refers to a spontaneous visual perception without corresponding external stimuli and ......
The gut microbiota plays an important role in regulating the pharmacokinetics and pharmacodynamics of many drugs.FLZ,a n......
Recent Progress in Non-motor Features of Parkinson’s Disease with a Focus on Circadian Rhythm Dysreg
Parkinson’s disease(PD)is the second most common neurodegenerative disease,which manifests with both motor and non-moto......
Parkinson’s disease(PD)is a common neurodegenerative disease.Despite a great deal of research on this disease,there is ......
The dosing of anti-Parkinson drugs is considered as the optimal control of the symptoms of PD,and increasing the dose of......
Non-invasive delivery of levodopa-loaded nanoparticles to the brain via lymphatic vasculature to enh
Levodopa(L-DOPA),a precursor of dopamine,is commonly prescribed for the treatment of the Parkinson’s disease(PD).Howeve......
lncRNA NEAT1 prompts autophagy and apoptosis in MPTP-induced Parkinson’s disease by impairing miR-37
Long non-coding RNAs(lncRNAs)play biological roles in brain disorder and neurodegenerative diseases.As the functions of ......
Astrocytes and astrocyte-related proteins play important roles in maintaining normal brain function, and also regulate p......
Glial cell line-derived neurotrophic factor (GDNF) plays an important role in the protection of dopaminergic neurons, bu......
目的介绍微电极导向同期双侧腹后苍白球毁损术治疗帕金森病的方法与效果.方法应用微电极电生理记录技术术对毁损靶点进行确认定位,......
Objective:To investigate the neuroprotective effects of Fructus Mume total flavone(FMF)against cell apoptosis and mitoch......
S-腺苷甲硫氨酸(SAMe,SAM,或AdoMet)是参与体内多种细胞代谢活动的一种重要的化合物,参与转甲基、转硫基和转氨基等人体中超过100种生物......
该系统可应用于柔性阵列压力传感器搭建的S型步态通道平台,采集帕金森患者动态足底压力分布数据,并通过以太网传输至PC机进行分析。......
Bone cement implantation syndrome during hip replacement in a patient with pemphigus and Parkinson’s
BACKGROUND Bone cement implantation syndrome(BCIS)is characterized by hypotension,arrhythmia,diffuse pulmonary microvasc......
Stem cell transplantation and/or adenoviral glial cell line-derived neurotrophic factor promote func
BACKGROUND Parkinson’s disease(PD)is a neurological disorder characterized by the progressive loss of midbrain dopamine......
Management of Parkinson’s Diseases with Microelectrode-guided Stereotactic Pallidotomy and Thalamoto
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Clinical features and relative factors of constipation in a cohort of Chinese patients with Parkinso
BACKGROUND Constipation as a most common non-motor symptom of Parkinson's disease(PD),has a higher prevalence compar......
Research on the effects of family care degree on stigma and psychosocial adaptation among the patien
Objective:This study aimed to investigate the status quo of family care degree,stigma and psychosocial adaptation of the......
Caveolin-1 downregulation promotes the dopaminergic neuron-like differentiation of human adipose-der
Previous studies have shown that caveolin-1 is involved in regulating the differentiation of mesenchymal stem cells.Howe......
Early involvement of gut is observed in Parkinson’s disease(PD) and symptoms such as constipation may precede motor sym......
AIM: To determine gastric emptying, blood pressure, mesenteric artery blood flow, and blood glucose responses to oral gl......
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Experimental Study on Dynamic Regulation of Acetylcholine in Striatum of Rat Parkinson Disease Model
In order to explore the role of acetylcholine in the pathogenesis of Parkinson’s disease (PD),the changes in the concen......
Parkinson’s disease(PD)is an age-related neurodegenerative disease caused by the progressive loss of dopaminergic(DA)ne......
Co-transplantation of macaque autologous Schwann cells and human embryonic nerve stem cells in treat
【正】Objective:To investigate the therapeutic effects of co-transplantation with Schwann cells(SCs) and human embryonic n......
This article analyses, on the basis of the pathophysiological grounds of various syndromes treated with deep brain stimu......
Ogilvie’s syndrome is an acute dilatation of a part or all of the colon and rectum without mechanical obstruction. The ......
Five-Year Outcomes of Bilateral Subthalamic Nucleus Stimulation in Japanese Patients with Parkinson’
Background: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is widely performed for medically refractory P......
Parkinson’s disease (PD) is a neurodegenerative disease mainly caused by motor disorders, mostly occurring in middle-ag......
Updates in the pathophysiological mechanisms of Parkinson’s disease: Emerging role of bone marrow me
AIM: To explore the approaches exerted by mesenchymal stem cells(MSCs) to improve Parkinson’s disease(PD) pathophysiolo......
AIM:To evaluate different promising magnetic resonance imaging(MRI) methods at 7.0 Tesla(T) for the pre-stereotactic vis......
Human adult olfactory epithelium contains neural progenitors (hONPs) which replace damaged cellular components throughou......
Parkinson’s disease (PD) is complex and most likely results from an unknown combination of genetic and environmental fa......
Medical and surgical therapies for patients with Parkinson’s disease (PD) are typically considered and initiated upon d......
The present study aimed to evaluate the correlation between the oral health status and the quality of life for people wi......
Caring for a person with Parkinson’s disease (PD) extends far beyond the ordinary exchange of assistance among people i......
Prenatal and Postnatal Exposures to 1-Methyl-4-phenyl-1,2,3,6-tetra Hydropyridine (MPTP) Impaired Mo
Dopamine cell bodies in the substantia nigra of the midbrain and with their terminals projecting to the neostriatum form......
Early-life stress has been shown to disrupt the programming of the hypothalamic-pituitary-adrenal (HPA) axis which may h......
We have performed a complete screening of the Parkin gene (PRKN2) and looked for p.Gly2019Ser (G2019S) and p.Arg1441Gly ......
Oxidative stress is one of the underlying causes of Parkinson’s disease (PD). Because of its antioxidant effect, we hyp......
Patients with Parkinson’s disease complain dizziness frequently. Postural hypotension and postural instablity are sugge......
The interaction between the dopaminergic and the serotonergic systems in the 6-OHDA rat model of Par
This review summarizes published results that are related to the coupling between the dopaminergic and the serotonergic ......
Diagnostics and rehabilitation of Parkinson’s disease (PD) presents the current information pertaining to etiology, ear......
Recent advances in pharmacological therapy of Parkinson’s disease: Levodopa and carbidopa protective
Parkinson’s disease is one of the most common progressive neurodegenerative disorder. It is characterized by the deplet......
Parkinson’s disease (PD) or Paralysis Agitans was first formally described in “An essay on the shaking palsy”, publis......
In the developing and adult brain, neurotrophic growth factors support the growth and protec tion of dopaminergic neuron......
Alpha-synuclein is the major component of Lewy bodies, insoluble protein aggregates, found in patients with Parkinson’s......
Motor symptoms are cardinal clinical features of Parkinson’s disease (PD). Progress in drug therapy and rehabilitation ......
Implementation and Validation of a Stride Length Estimation Algorithm, Using a Single Basic Inertial
As low cost and highly portable sensors, inertial measurements units (IMU) have become increas-ingly used in gait analys......