RIBAVIRIN相关论文
Qingkailing Injection(清开灵注射液)for Treatment of Children Pneumonia Induced by Respiratory Syncytial Vi
Objective:To evaluate the efficacy and safety of Qingkailing Injection(清开灵注射液,QKL) for treatment of children pneum......
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Pure red cell aplasia caused by pegylated interferon-α-2a plus ribavirin in the treatment of chronic
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Predictors of response to antiviral therapy in patients with chronic hepatitis C from Pakistani popu
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Controversies’ clarification regarding ribavirin efficacy in measles and coronaviruses: Comprehensiv
BACKGROUND Ribavirin is a broad-spectrum nucleoside antiviral drug with multimodal mechanisms of action,which supports i......
Combination therapy with peginterferon (pegIFN)-α and ribavirin (RBV) has been the standard of care (SOC) for chronic h......
Potential of G-CSF supplementation to counter the neutrophil effects of standard PEG-IFNα plus ribav
Objective To investigate the effects of the granulocyte colony stimulating factor (G-CSF) with pegylated interferon alph......
近期,三个独立的研究小组分别通过全基因组关联分析(genome-wide association studies,GWAS)鉴定发现,IL-28B的基因多态性与聚乙二......
Alanine aminotransferase normalization at week 8 predicts viral response during hepatitis C treatmen
AIM:To investigate alanine aminotransferase(ALT)and sustained virological response(SVR)in chronic hepatitis C(CHC)during......
Direct-acting antiviral agents(DAAs)for hepatitis C virus(HCV)infection are one of the major advances in its medical tre......
Are metabolic factors still important in the era of direct antiviral agents in patients with chronic
The high rate of sustained viral response(SVR)to boceprevir or telaprevir-based triple therapy in hepatitis C(HCV)-relat......
In this review,we discuss recent advances in nucleic acid-based therapeutic technologies that target hepatitis C virus(H......
Efficacy and safety of pegylated interferon in patients with chronic hepatitis C in China: meta-anal
Objective To evaluate the efficacy and safety of pegylated interferon in patients with chronic hepatitis C in China.Meth......
Investigation of antiviral efficacy in patients with chronic hepatitis C originating from a same blo
Objective To investigate the antiviral efficacy of standard treatment with interferon(IFN)-α2b and ribavirin(RBV)in pat......
The use of triple therapy for hepatitis C not only increases the rate of sustained virological responses compared with t......
AIM:To investigate the safety and efficacy of a Hansenula-derived PEGylated(polyethylene glycol)interferon(IFN)-alpha-2a......
AIM:To investigate the utility of phosphorus-31(31P)magnetic resonance spectroscopy(MRS)as a noninvasive test for assess......
AIM:To determine the frequencies of mutations that cause inherited monogenic liver disorders in patients with chronic he......
New nucleos(t)ide analogues(NAs) with high genetic barrier to hepatitis B virus(HBV) resistance(such as entecavir, tenof......
AIM:To investigate the early viral kinetics and interleukin-28B(IL28B)polymorphisms of hepatitis C genotype6 during pegy......
Hepatitis C virus(HCV)infection represents a major health issue worldwide due to its burden of chronic liver disease and......
The prevalence of hepatitis C virus(HCV) infection in patients on maintenance hemodialysis(MHD) is relatively higher tha......
Pathogenesis and significance of hepatitis C virus steatosis:An update on survival strategy of a suc
Hepatitis C virus(HCV)is a successful pathogen on the grounds that it exploits its host’s metabolism to build up viral ......
A new treatment paradigm for hepatitis C is that the treatment must include an existing direct-acting antiviral agent, n......
目的:评价聚乙二醇干扰素α-2a(polyethylene glycol interferon alpha-2a,PEG-IFNα-2a)联合利巴韦林(ribavirin,RBV)治疗转氨酶......
Hepatitis C virus(HCV) affects about 3% of the world’s population and peaks in subjects aged over 40 years. Its prevale......
Telaprevir- and boceprevir-based tritherapies in real practice for F3-F4 pretreated hepatitis C viru
AIM:To assess,in a routine practice setting,the sus-tained virologic response(SVR) to telaprevir(TPV) or boceprevir(BOC)......
Chronic hepatitis C(CHC) infection affects almost 3% of the global population and can lead to cirrhosis, liver failure, ......
The purpose of the present review is to summarise the current knowledge on the association between single nucleotide pol......
Age-related differences in response to peginterferon alfa-2a/ribavirin in patients with chronic hepa
AIM: To evaluate the safety and efficacy of pegylated interferon alfa-2a and ribavirin therapy in elderly patients with ......
IL28B polymorphism genotyping as predictor of rapid virologic response during interferon plus ribavi
AIM: To clarify the association of interleukin-28B(IL28B) single nucleotide polymorphisms(SNPs) with hepatitis C virus(H......
Hepatitis E viral infection has traditionally been considered an acute, self-limited, water borne disease similar to hep......
Boceprevir early-access for advanced-fibrosis/cirrhosis in Asia-pacific hepatitis C virus genotype 1
AIM:To examined the efficacy and safety of treatment with boceprevir,PEGylated-interferon and ribavirin(PR)in hepatitis ......
Direct-acting antiviral-based triple therapy on alpha-fetoprotein level in chronic hepatitis C patie
AIM: To investigate the impact of telaprevir-based triple therapy on the serum alpha-fetoprotein(AFP) level of chronic h......
AIM: To evaluate the efficacy of pegylated interferon in Iranian chronic hepatitis C patients in relation to interferon-......
Effectiveness and safety of first-generation protease inhibitors in clinical practice:Hepatitis C vi
AIM:To evaluates the effectiveness and safety of the first generation,NS3/4A protease inhibitors(PIs) in clinical practi......
Hepatitis C virus(HCV) infection may lead to significant liver injury, and viral, environmental, host, immunologic and g......
Crimean-Congo hemorrhagic fever (CCHF) is a zoonotic viral infection that is a serious threat to humans. The disease is ......
建立了兽药制剂中利巴韦林的高效液相色谱测定方法,对兽药制剂中利巴韦林的提取、净化和色谱条件进行了优化。以p H 2.5的水作为溶......
Novel pyrazole fused heterocyclic ligands:Synthesis,characterization,DNA binding/cleavage activity a
A series of novel pyrazole fused heterocyclic derivatives were synthesized via a two-step procedure or a one-pot two ste......
Hepatitis C in the pediatric population: Transmission, natural history, treatment and liver transpla
The number of children affected by the hepatitis C virus(HCV) in the United States is estimated to be between 23000 to 4......
AIM:To study current treatment options for pediatric hepatitis C infection and their associated success rates.METHODS:We......
Synthesis of tetrazole containing 1,2,3-thiadiazole derivatives via U-4CR and their anti-TMV activit
A series of novel tetrazole containing 1,2,3-thiadiazole derivatives were designed and synthesized via Ugi reaction. The......
Pegylated interferon(IFN)α-2a or 2b in combination with ribavirin for children aged 3 years and older is the standard t......
Potassium dehydroandrographolide succinate injection for treatment of infantile pneumonia:a systemat
OBJECTIVE:To evaluate systematically the clinical efficacy and safety of potassium dehydroandrographolide succinate inje......
Hepatitis C virus(HCV)is a serious public health problem affecting 170 million carriers worldwide.It is a leading cause ......